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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 100 (1978), S. 1205-1210 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 28 (1906), S. 877-882 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1459
    Keywords: Key words Upper medullary ; infarction ; Facial paresis ; Brainstem ; Transcranial magnetic stimulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We describe two patients with upper medullary infarctions showing ipsilateral facial weakness and relative sparing of the upper facial muscles. Electrophysiological follow-up using transcranial magnetic stimulation of the motor cortex in combination with stimulation of the peripheral facial nerve disclosed a supranuclear (corticofacial) tract lesion in one patient and a partial nuclear/infranuclear intra-axial facial nerve lesion in another.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 23 (1982), S. 335-338 
    ISSN: 1432-1041
    Keywords: ferrous ascorbate ; iron absorption ; iron deficiency ; mucosal transfer ; mucosal uptake
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The absorption of a pharmacological dose of iron was assessed by determination of mucosal uptake, mucosal transfer and retention of 33 mg Fe(II) as ferrous sulphate and ferrous ascorbate. 20 subjects were studied in a cross-over trial, 11 with normal iron stores and 9 with iron deficiency according to the serum ferritin concentration. The activity of59Fe and51Cr (administered as a non-absorbable indicator) was measured by whole-body counting. There was no difference in absorption between the two iron compounds in normal subjects. Absorption of ferrous ascorbate averaged 52% higher than ferrous sulphate in subjects with iron deficiency. The difference was the result of higher mucosal uptake, probably because oxidation of Fe(II) in the alkaline milieu of the intestine, which leads to formation of non-absorbable Fe(III) complexes, was prevented. The mucosal transfer fraction of both compounds was identical.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    BBA - Protein Structure 578 (1979), S. 107-115 
    ISSN: 0005-2795
    Keywords: Fibrin ; Fibrinogen ; Raman spectroscopy
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 66 (1995), S. 274-276 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Low-loss optical waveguides have been produced in z-cut Sr0.6Ba0.4Nb2O6 (SBN:60) and electro-optic modulation has been demonstrated at a wavelength of 1.3 μm. The refractive index increase responsible for waveguiding results from a strain produced by a SiO2 film which has been deposited on the surface of the substrate at 320 °C. The waveguides are formed in the crystal by dry etching of channels in the strain film. The resulting optical waveguides support both polarizations. Propagation loss values of 0.7 dB/cm for TM polarization and 1.6 dB/cm for TE polarization were measured. Electro-optic modulation up to 22 MHz was performed on repoled samples using coplanar electrodes. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 60 (1992), S. 407-409 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Channel waveguides have been produced in LiNbO3, LiTaO3, and BaTiO3 ferroelectric crystals by depositing thick SiO2 films at an elevated temperature and patterning them by reactive ion etching. The static strain resulting from the large thermal expansion mismatch between the substrate and film causes a localized increase in the refractive index via the strain-optic effect. In addition, an electro-optic contribution to the index increase is believed to result from a surface charge distribution which compensates the electric field due to the piezoelectric effect. Single-mode waveguides at a wavelength of 0.633 μm for both polarizations have been produced in x-cut LiNbO3, with losses of 0.8 dB/cm for TE polarization and 0.9 dB/cm for TM polarization. The 11-μm-wide channel waveguides were formed by a z-axis strain induced by a 2.8-μm-thick SiO2 film deposited at 300 °C. Electro-optic modulation was also demonstrated in these waveguides. Guiding for both polarizations was also observed in LiTaO3 and BaTiO3 channel waveguides at 0.83 μm wavelength.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 67 (1995), S. 1381-1383 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Characterization of bulk single crystals and optical waveguides in Ba1−xSrxTiyNb2−yO6 (BSTN) indicate it to be a promising new ferroelectric material for electrooptic devices. The electro-optic coefficient r33 is measured to be 218±12 pm/V, a factor of 7 greater than LiNbO3. Data on refractive indices, dielectric constant, and Curie temperature Tc in bulk samples are also presented. Strain-induced waveguides in Z-cut samples exhibited low losses (1.8 dB/cm for TM polarization and 2.5 dB/cm for TE polarization) at a wavelength of 1.3 μm. Electro-optic modulation was demonstrated in these waveguides to frequencies (approximately-greater-than)100 MHz. A "self-poling'' effect was found, whereby strong electro-optic modulation is observed in the strain waveguides without repoling the crystal after processing at temperatures far above Tc. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford UK : Blackwell Science Ltd
    Alimentary pharmacology & therapeutics 15 (2001), S. 0 
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Both anaemia of iron deficiency and anaemia of chronic disease are frequently encountered in inflammatory bowel disease. Anaemia of iron deficiency is mostly due to inadequate intake or loss of iron. Anaemia of chronic disease probably results from decreased erythropoiesis, secondary to increased levels of proinflammatory cytokines, reactive oxygen metabolites and nitric oxide.Assessment of the iron status in a condition associated with inflammation, such as inflammatory bowel disease, is difficult. The combination of serum transferrin receptor with ferritin concentrations, however, allows a reliable assessment of the iron deficit.The best treatment for anaemia of chronic disease is the cure of the underlying disease. Erythropoietin reportedly may increase haemoglobin levels in some of these patients. The anaemia of iron deficiency is usually treated with oral iron supplements. Iron supplementation may lead to an increased inflammatory activity through the generation of reactive oxygen species. To date, data from studies in animal models of inflammatory bowel disease support the theoretical disadvantage of iron supplementation in this respect. The results, however, cannot easily be extrapolated to the human situation, because the amount of supplemented iron in these experiments was much higher than the dose used in patients with iron deficiency.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Scandinavian journal of immunology 46 (1997), S. 0 
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Hereditary haemochromatosis (HH) monocytes have a decreased antibody mediated phagocytosis of rabbit erythrocytes and Staphylococcus aureus compared to control monocytes. In order to investigate whether this decrease could be attributed to a different level of expression of Fcγ receptors (FcγR) or complement receptors (CR), which cooperate even in the absence of complement, the surface expression of these receptors was determined on monocyte-enriched suspensions. In contrast to what was expected, HH monocytes displayed a significantly higher level of FcγRI and FcγRIIa as compared to healthy donor monocytes, but these differences were very small. The expression of the other receptors studied were similar for both groups. The heat-inactivated mouse serum used for opsonizing the erythrocytes mainly contained mouse IgG1. Two genetically different forms of FcγRIIa are known, each with a different affinity for mouse IgG1 antibodies. Therefore, the FcγRIIa polymorphism in monocytes (MN) of both groups was also investigated. A similar distribution was found for patients and healthy donors. In addition, the extent of erythrophagocytosis of both donors and patients was independent of FcγRIIa allotype. Our results indicate that the altered phagocytosis by HH monocytes cannot be attributed to a different level of expression of receptors involved in phagocytosis or to FcγRIIa polymorphism.
    Type of Medium: Electronic Resource
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