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  • 1
    Electronic Resource
    Electronic Resource
    [s.l.] : Macmillian Magazines Ltd.
    Nature 404 (2000), S. 759-761 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Through cardiac looping during embryonic development, paths of flow through the mature heart have direction changes and asymmetries whose topology and functional significance remain relatively unexplored. Here we show, using magnetic resonance velocity mapping, the asymmetric redirection ...
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1615-2573
    Keywords: Mitral flow ; Velocity profile ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We used magnetic resonance imaging (MRI) velocity mapping to assess the velocity profile of early diastolic mitral inflow in 11 normal subjects. Velocity maps of left ventricular inflow were obtained in the horizontal long axis of the left ventricle at the time of peak early diastolic filling. Velocity profile curves across the mitral inflow were obtained at 1-cm intervals from the mitral ring to 4 cm into the cavity. The jet width was 3.06 ± 0.64cm at the mitral ring level, increasing to 3.6 ± 0.61 cm at 4cm. The peak/mean velocity was 1.2 ± 0.07 at the mitral ring and increased to around 1.4 at 3–4cm from the mitral ring. The point at which the peak velocity was recorded at each level was skewed towards the septal side by 10%–13% of jet width from the center at the mitral ring and 2–4cm from the ring. However, at a depth of 1 cm, corresponding to the mitral tip level, the peak velocity was at the center of the jet. The ratio of vertical and horizontal dimensions of the jet cross section was 1.11 ± 0.05. Thus, the mitral inflow velocity profile is relatively flat at the mitral ring and tip level; the inflow jet cross section is effectively circular.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    The international journal of cardiovascular imaging 16 (2000), S. 175-184 
    ISSN: 1573-0743
    Keywords: magnetic resonance imaging ; convex projection ; flow visualisation ; texture synthesis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Magnetic resonance (MR) imaging is a versatile technique for providing detailed information on blood vessel morphology and function. With its ability to acquire multi-dimensional cine flow data, MR is also an important tool for providing insight into blood flow patterns in vivo. The purpose of this paper is to describe the application of texture synthesis for flow visualisation. Two related issues are addressed, one is the removal of image noise from the acquired velocity data to ensure a correct representation of the underlying flow structure, and the other is the formation of transient streamlines through flow texture synthesis. The process of noise removal is achieved by using a convex projection algorithm based on the principle of mass conservation, whereas transient streamlines are formed via an iterative orientated pattern formation and enhancement procedure. The method described provides realistic visualisation of the flow patterns and avoids distortions caused by integration errors associated with conventional streamline tracking techniques. Effectiveness of the method applied to MR flow data acquired in healthy volunteers and patients is demonstrated.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1352-8661
    Keywords: MRI ; velocity mapping ; stenosis ; hemodynamics ; coarctation ; valve disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics
    Notes: Abstract Shortening the echo times of magnetic resonance (MR) sequences used for phase-shift velocity mapping to 3.6 ms has extended use of the technique to measurement of velocities in turbulent, poststenotic jet flows. We used a 0.5-T MR machine and field even-echo rephasing (FEER) sequences with 3.6 ms echo times for jet velocity mapping.In vitro trials used continuous flow through a phantom with a 6-mm stenosis. Fifteen patients with mitral and/or aortic valve stenosis and 20 patients with repaired aortic coarctation were studied prospectively, with Doppler ultrasonic measurement of peak jet velocity performed independently on the same day. The clinical contribution of MR jet velocity mapping, used during a 3-year period in 306 patients with congenital and acquired disease of heart valves, great vessels, and conduits, was assessed retrospectively. The 3.6-ms sequence allowed accurate measurement of jet velocities up to 6 m s−1 in vitro (r=0.996). Prospective studies in patients showed good agreement between MR and Doppler measurements of peak velocity:n=38; range, 1.2–6.1 m s−1; mean, 2.7 m s−1; mean of differences (Doppler-MR), 0.22 ms−1; standard deviation of differences, ±0.38 m s−1 (±14%). MR jet velocity mapping proved particularly valuable for assessment and localization of stenoses at sites where ultrasonic access was limited. The technique represents a diagnostic advance which can obviate the need for catheterization in selected cases.
    Type of Medium: Electronic Resource
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