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  • 1
    Electronic Resource
    Electronic Resource
    Histological and microbiological aspects of ligature-induced periodontitis in beagle dogs (1996)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of clinical periodontology 23 (1996), S. 0 
    Details
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract This study was designed to investigate, using 6 beagle dogs, the levels of selected putative pathogens in healthy sites, in gingivitis sites, and in sites with histologically confirmed attachment loss. Levels of attachment loss increased with increasing periods of ligation and reached a maximum of 0.15 mm at 57 days. Both histological attachment level and histological pocket depth were found to vary significantly with health/disease status (P〈0.0001). Higher numbers of total colony-forming units were seen for ligated sites than for healthy and gingivitis sites. Levels of Purphyromonas gingivalis and Prevotella intermedia also changed significantly with health/disease status (p〈0.001). These organisms showed their greatest increases at the time of the most intense attachment loss. Higher levels of Fusobaeterium nucleatum were seen in the gingivitis sites than in healthy or Heated sites. Low levels of Campylobacter rectus and Capnocytophaga spp. were detected throughout. The morphometric microbiological analysis revealed unexpectedly high %s of motile rods, while spirochetes were found in very low %s. The total number of bacterial cells detected using phase contrast microscopy was not found to vary significantly. None of the morphotypes were demonstrated as showing significant changes with health/disease status.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-051X.1996.tb00551.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Association of crevicular fluid elastase-like activity with histologically-confirmed attachment loss in ligature-induced periodontitis in beagle dogs (1998)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of clinical periodontology 25 (1998), S. 0 
    Details
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract. Experimental periodontitis was induced using ligatures in 6 beagle dogs over 57 days. Levels of elastase like activity in healthy sites, gingivitis sites, and in sites ligated for different time points were analyzed with respect to levels of histologically confirmed attachment loss. Attachment loss increased with increasing periods of ligation and reached a maximum of 0.15 mm at 57 days. Maximum loss of histological attachment was found to coincide with the period of maximum enzyme activity; during the first 7 days of ligature. Spearman correlation analysis of enzyme activity with attachment loss yielded a significant correlation (0.73, p=0.0396). The healthy and gingivitis sites were found to have minimal levels of enzyme activity throughout. Thus, this prospective study in beagle dogs found a relationship between histologically confirmed attachment loss and increased levels of elastase like activity indicating the probable usefulness of this parameter, either alone or in conjunction with other markers, for disclosing active periodontitis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-051X.1998.tb02457.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    The determination of uranium using short-lived fission products by cyclic and other modes of activation analysis (1987)
    Springer
    Journal of radioanalytical and nuclear chemistry 112 (1987), S. 277-283 
    Details
    ISSN: 1588-2780
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract The determination of elemental concentration in biological and environmental samples through the detection of short-lived nuclides has been of considerable interest in the last few years. In this context the relative advantages and disadvantages of cyclic activation analysis (CAA) with respect to single conventional one-shot irradiation and counting sequence (for one sample or replicate samples) and what has been termed pseudo-cyclic activation have been discussed with conflicting interpretations. It is the objective of this study to demonstrate through the irradiation of uranium standards by measurement of short-lived fission products how each mode of activation is best utilised. Application of CAA to the problem, in order to enhance signal-to-noise ratio, must also take into account an increasing dead-time with each cycle and therefore mass fractionation of a given sample and standard are investigated for replicate and pseudo-cyclic activation conditions. The variation of timing parameters in the cyclic mode, as well as irradation in a mixed reactor flux and epi-cadmium neutron flux, produces a set of equations from which half-life can be determined to confirm fission product identification in these complex gamma-ray spectra.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02132360
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    The use of simulation for the optimisation of the signal-to-noise ratio in cyclic activation analysis (1987)
    Springer
    Journal of radioanalytical and nuclear chemistry 110 (1987), S. 67-77 
    Details
    ISSN: 1588-2780
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract It is always useful to predict the result of an experiment without having to carry it out. In cyclic activation analysis where the signal-to-noise ratio for the detection of short-lived nuclides in a given matrix is particularly sensitive to the value of the timing parameters, determination of the best conditions for the detection of a nuclide of interest, without resort to preliminary experiments, is most helpful. Simulation and optimisation of a gamma-ray spectrum is derived for a sample irradiated in cyclic mode. The simulation includes consideration of photopeak, Compton continuum, single and double escape peaks and bremsstrahlung. The simulation output forms the input to the signal-to-noise ratio optimisation routine. Consequently the sensitivities, and detection limits for the isotopes of interest can be deduced from the optimised spectrum. Interference from other gamma-lines is identified, if applicable. In addition, a graphical output of the simulated spectrum and a listing of the optimised activation parameters, detection limits and sensitivites are produced. The programme has been extended to include simulation of conventionally neutron activated samples. Examples for standard reference materials are given as illustrations, together with measured spectra.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02055011
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    Paper (German National Licenses)
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