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  • 1
    Electronic Resource
    Electronic Resource
    Abdominal CT in familial Mediterranean fever: a case report (1998)
    Springer
    Abdominal imaging 23 (1998), S. 147-149 
    Details
    ISSN: 1432-0509
    Keywords: Key words: Abdomen—Perotonitis—Imaging—Computed tomography.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. In order to clarify abnormal findings at abdominal ultrasound (suspicion of late abscess subsequent to appendectomy) in a young male patient with known familial Mediterranean fever (FMF), a helical CT examination of the abdomen was performed. At CT, extensive serositis of the lower abdomen was detected. Findings at CT were verified 2 weeks later at laparoscopy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002619900308
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  • 2
    Electronic Resource
    Electronic Resource
    Histological and microbiological aspects of ligature-induced periodontitis in beagle dogs (1996)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of clinical periodontology 23 (1996), S. 0 
    Details
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract This study was designed to investigate, using 6 beagle dogs, the levels of selected putative pathogens in healthy sites, in gingivitis sites, and in sites with histologically confirmed attachment loss. Levels of attachment loss increased with increasing periods of ligation and reached a maximum of 0.15 mm at 57 days. Both histological attachment level and histological pocket depth were found to vary significantly with health/disease status (P〈0.0001). Higher numbers of total colony-forming units were seen for ligated sites than for healthy and gingivitis sites. Levels of Purphyromonas gingivalis and Prevotella intermedia also changed significantly with health/disease status (p〈0.001). These organisms showed their greatest increases at the time of the most intense attachment loss. Higher levels of Fusobaeterium nucleatum were seen in the gingivitis sites than in healthy or Heated sites. Low levels of Campylobacter rectus and Capnocytophaga spp. were detected throughout. The morphometric microbiological analysis revealed unexpectedly high %s of motile rods, while spirochetes were found in very low %s. The total number of bacterial cells detected using phase contrast microscopy was not found to vary significantly. None of the morphotypes were demonstrated as showing significant changes with health/disease status.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-051X.1996.tb00551.x
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  • 3
    Electronic Resource
    Electronic Resource
    Association of crevicular fluid elastase-like activity with histologically-confirmed attachment loss in ligature-induced periodontitis in beagle dogs (1998)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of clinical periodontology 25 (1998), S. 0 
    Details
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract. Experimental periodontitis was induced using ligatures in 6 beagle dogs over 57 days. Levels of elastase like activity in healthy sites, gingivitis sites, and in sites ligated for different time points were analyzed with respect to levels of histologically confirmed attachment loss. Attachment loss increased with increasing periods of ligation and reached a maximum of 0.15 mm at 57 days. Maximum loss of histological attachment was found to coincide with the period of maximum enzyme activity; during the first 7 days of ligature. Spearman correlation analysis of enzyme activity with attachment loss yielded a significant correlation (0.73, p=0.0396). The healthy and gingivitis sites were found to have minimal levels of enzyme activity throughout. Thus, this prospective study in beagle dogs found a relationship between histologically confirmed attachment loss and increased levels of elastase like activity indicating the probable usefulness of this parameter, either alone or in conjunction with other markers, for disclosing active periodontitis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-051X.1998.tb02457.x
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  • 4
    Electronic Resource
    Electronic Resource
    reply: Bioenergetics Proton pumping by cytochrome c oxidase (1999)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 402 (1999), S. 603-603 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Verkhovsky et al. reply Ten years ago, one of us showed that all proton translocation by cytochrome c oxidase seems to be coupled to the enzyme's oxidative catalytic half-cycle. This led to the assumption that all proton translocation takes place during this half of the cycle. ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/45135
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  • 5
    Electronic Resource
    Electronic Resource
    Retinoids Activate Superoxide Production by Polymorphonuclear Leucocytes (1985)
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 21 (1985), S. 0 
    Details
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Retinol and retinoic acid were effective activators of oxygen consumption by human polymorphonuclear leucocytes (PMN) in micromolar concentrations. In contrast, retinyl acetate was ineffective as an activator. Retinol caused activation only after a lag lime, the length of which depended on retinol concentration. Oxygen consumption was due to Superoxide production by PMN. Superoxide production was observed as Superoxide dismutase-inhibitable cytochrome c reduction. Previously, retinoids have been reported lo inhibit PMN activation by phorhol myristate acetate, a tumour promoter. This retinoid-induced inhibition of PMN activation has been suggested to be a mechanism by which retinoids may protect against carcinogenesis in animals. However, the retinoid concentra-lions at which PMN inhibition was reported were much higher than those found to cause activation in this study. We found lhat retinoic acid slightly inhibited phorbol myristate acetate-activated Superoxide production, but only at concentrations that caused activation. In contrast, activation by formyl-Met-Lcu-Phe was effectively inhibited at a retinoic acid concentration that did not cause activation by itself.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-3083.1985.tb01425.x
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  • 6
    Electronic Resource
    Electronic Resource
    A longitudinal microbiological study on osseointegrated titanium implants in partially edentulotis patients (1993)
    Copenhagen : Munksgaard International Publishers
    Clinical oral implants research 4 (1993), S. 0 
    Details
    ISSN: 1600-0501
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The aim was to longitudinally follow the colonization of putative periodontal pathogens on titanium implants in partially edentulous patients. Nineteen individuals, who were partially edentulous and were on the waiting-list to be treated with titanium fixtures, were included in the study. They were treated for periodontal disease with oral hygiene instructions and supra- and subgingival debridement and were left for maintenance. Full-mouth recordings of each patient were performed at baseline, including attachment level and probing pocket depth. Bleeding was provoked and visible plaque were registered. Subgingival samples were taken for examination of Porphyromonas gingivalis, Prevotella intermedia and Actinobacillus actinomycetemcomitans. Bridge connection was completed 1 month after abutment connection. The bone level was registered on radiographs. The patients were followed with clinical registrations and subgingival samples at 6, 12, 24 and 36 months. No significant changes in pocket depth, attachment level, bleeding on probing or plaque score occurred during the experimental period. The number of individuals positive at teeth and abutments for the various bacterial species reached approximately similar levels at 6 months. No significant changes over time were seen. Comparison between bone height. seen on radiographs, at abutments after 2, 12 and 36 months gave only 3 sites with bone loss of 〉 0.5 mm. All these sites were found in one patient and were accompanied by P. intermedia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-0501.1993.040301.x
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  • 7
    Electronic Resource
    Electronic Resource
    Die infektiöse Spondylitis Eine retrospektive Auswertung der MRT-Merkmale (1997)
    Springer
    Der Radiologe 37 (1997), S. 139-144 
    Details
    ISSN: 1432-2102
    Keywords: Schlüsselwörter Spondylitis ; Spondylodiszitis ; Wirbelkörper ; Bandscheibe ; Kernspintomographie ; Key words Spondylitis ; Spondylodiscitis ; Spine ; Intervertebral disc ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Aim and methods: The aim of the present study was to evaluate the MRI criteria of infectious spondylitis (spondylodiscitis). The MR images of 23 patients suffering from spondylodiscitis (78 % unspecific, 22 % specific) were retrospectively analyzed. Results: The height of the intervertebral discs involved was normal in 40 %, reduced in 43 % and increased in 17 % of the cases. The most common findings can be summarized in an MR triad: 1) The vertebral bodies involved are hypointense in T1-weighted images (100 %) with a lack of delineation of the intervertebral discs (53 %). 2) The injection of Gd-DTPA yields an enhancement of the vertebral bodies involved and intervertebral discs (95 % and 74 % respectively). 3) The vertebral bodies and intervertebral discs are hyperintense in T2-weighted sequences (76 % and 90 % respectively). When present, a paravertebral or intraspinal extension of the infection was isointense compared with the adjacent involved vertebral body in the majority of the patients. A differentiation between unspecific and specific etiology based on the MR images was not possible. Conclusions: The vertebral bodies affected were usually hypointense in T1-W with enhancement after the administration of Gd-DTPA and hyperintense in T2-W. The discs involved were usually hyperintense in T2-W and demonstrated an inhomogeneous enhancement.
    Notes: Zusammenfassung Um die kernspintomographischen Merkmale der Spondylitis zu überprüfen, wurden die MRT-Bilder von 23 Patienten mit einer Spondylitis (78 % unspezifisch, 22 % spezifisch) retrospektiv analysiert; 40 % der befallenen Bandscheiben zeigten eine normale Höhe, 43 % waren verschmälert und 17 % zeigten eine Höhenzunahme. Die häufigsten Veränderungen lassen sich in einer MRT-Trias zusammenfassen: 1. In T1-gewichteten Sequenzen sind die befallenen Wirbelkörper hypointens (100 %) und die Bandscheiben nicht abgrenzbar (53 %). 2. Wirbelkörper und Bandscheiben nehmen Kontrastmittel auf (95 bzw. 74 %). 3. Wirbelkörper und Bandscheiben sind in T2-gewichteten Sequenzen hyperintens (76 bzw. 90 %). Dabei stellt sich ein paravertebraler Weichteilbefall in allen Sequenzen isointens zum befallenen Wirbelkörper dar. Eine Differenzierung zwischen unspezifischer und spezifischer Ätiologie war kernspintomographisch nicht möglich.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001170050186
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  • 8
    Electronic Resource
    Electronic Resource
    Finite element modelling of calendering — some aspects of the effects of temperature gradients and structure inhomogeneities (1996)
    Springer
    Journal of materials science 31 (1996), S. 3159-3166 
    Details
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The compression of a paper web in a calender nip has been simulated using the finite element method. The mechanical properties of the paper were allowed to vary in the thickness and machine directions of the web. This was done in order to model the influence of temperature gradients as well as density variations (due to the presence of fibre floes) on the deformation behaviour in the nip. Paper was assumed to be an elastic-plastic material exhibiting strain hardening. The yielding behaviour was governed by the Drucker-Prager yield condition. Simulations of the deformation behaviour when paper was subjected to a temperature gradient, clearly revealed that the deformation gradually became more concentrated towards the surface layers as the temperature of the surface increased. This is in accordance with experimental results which indicate that temperature-gradient calendering promotes the surface properties, whereas the bulk of the structure is preserved. Modelling the deformation behaviour of a structure containing density variations reveals that the paper may contain an inhomogeneous strain distribution after unloading, i.e. after passage through the nip.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00354662
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  • 9
    Electronic Resource
    Electronic Resource
    Galanin-, neuropeptide Y- and enkephalin-like immunoreactivities in catecholamine-storing paraganglia of the fetal guinea pig and newborn pig (1989)
    Springer
    Cell & tissue research 255 (1989), S. 495-504 
    Details
    ISSN: 1432-0878
    Keywords: Paraganglia ; Neuropeptide ; Immunocyto chemistry ; Noradrenaline ; Dopamine ; Cholecystokinin ; Calcitonin gene-related peptide ; Vasoactive intestinal polypeptide ; Guinea pig ; Pig
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The occurrence and distribution of several neuropeptides and transmitter enzymes have been investigated by means of indirect immunofluorescence histochemistry in preaortal and carotid body-like paraganglia of the fetal guinea pig and the newborn pig. Preaortal paraganglia from the celiac and inferior mesenteric ganglion regions in fetal guinea pigs showed cell bodies immunoreactive (IR) for tyrosine hydroxylase (TH), dopamine β-hydroxylase (DBH), neuropeptide Y (NPY), galanin (GAL) and metenkephalin (ENK). Almost all cells were IR for TH and DBH, whereas NPY-like immunoreactivity (-LI), GAL-LI and ENK-LI occurred less frequently. Direct double-labeling revealed the coexistence of NPY/GAL, NPY/ENK and GAL/ENK in paraganglion cells from the celiac and inferior mesenteric region. Nerve fibers and terminals were IR for ENK; fibers IR for calcitonin-gene-related peptide (CGRP) were present in the inferior mesenteric ganglion region. Preaortal paraganglia cells from the newborn pig showed TH-LI, DBH-LI, GAL-LI and ENK-LI, the distribution pattern being similar to that seen in the guinea pig; however, NPY-LI was absent. Carotid-body-like paraganglia from the newborn pig showed cell bodies IR to TH, GAL and ENK. Few cells were seen with DBH-LI. A rich supply of nerve fibers with CGRP-LI was present; some fibers exhibited ENK-LI and CCK-LI. In the adjacent superior cervical ganglion, ganglion cell bodies showed immunoreactivity to TH, DBH and NPY. A small number of cells were positive for GAL, CGRP and vasoactive intestinal polypeptide (VIP). Physiological activation of the paraganglia, leading to release or increase in catecholamines, may also change the content of the neuropeptides present in the paraganglia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00218784
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