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  • 1
    Electronic Resource
    Electronic Resource
    Difference in nitroglycerin dose-response in the venous and arterial beds (1980)
    Springer
    European journal of clinical pharmacology 18 (1980), S. 455-460 
    Details
    ISSN: 1432-1041
    Keywords: nitroglycerin ; plasma concentrations ; haemodynamic effects ; venous distension ; arterial resistance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary In twelve healthy volunteers given nitroglycerin sublingually (1.6 mg) or epicutaneously (12 mg), venous distensibility was found to be maximal, even at low plasma concentrations (〈0.2 ng/ml); there was no further change with increasing concentrations. Peripheral arterial resistance, on the other hand, decreased progressively with rising plasma concentrations and no distinct plateau was demonstrable, even at the highest plasma concentration measured (〉2.0 ng/ml).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00874655
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  • 2
    Electronic Resource
    Electronic Resource
    Plasma concentrations and haemodynamic effects of nitroglycerin during and after intravenous infusion in healthy volunteers (1982)
    Springer
    European journal of clinical pharmacology 23 (1982), S. 99-106 
    Details
    ISSN: 1432-1041
    Keywords: nitroglycerin ; i.v. infusion ; plasma level ; haemodynamic effects
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The effects of nitroglycerin, infused intravenously at 3.4 and 7.5 µg/min over 30 min, on haemodynamic parameters were determined in the morning and the afternoon in a randomized, placebo-controlled study in 5 healthy volunteers. The mean steady-state concentrations of nitroglycerin reached in the plasma during the infusions of 3.4 and 7.5 µg/min were 0.35±0.06 ng/ml and 0.64±0.22 ng/ml, respectively. Wide inter-individual variation was noted. The nitroglycerin-induced increase in the orthostatic rise in heart rate and the change in digital-pulse-wave morphology roughly paralleled the plasma concentration, whereas the reduction in systolic blood pressure in the upright position was still evident 15 mins after the infusion, i.e. when nitroglycerin was no longer measurable in plasma. No significant diurnal variation in vascular sensitivity to the vasodilative action of nitroglycerin was demonstrable. The change in pulse-wave morphology resulting from the reduction in peripheral resistance (shift of the dicrotic wave in the descending limb towards the base-line) proved to be the most sensitive haemodynamic parameter.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00545962
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Surimi from Fillet Frames of Channel Catfish (1996)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 61 (1996), S. 0 
    Details
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Surimi was prepared with channel catfish mince recovered from fillet frames. The deboned meat was washed once, twice, or three times with water for surimi processing. Unwashed mince was also blended with cryoprotectants for surimi processing. Heat-induced gels were prepared using washed or unwashed catfish surimi with or without starch. Results indicated no differences (P〉0.05) in textural properties and Hunter color values due to number of washes in those gels prepared with washed surimi. Differences (P〈0.05) in proximate composition, textural properties and Hunter color values were found between gels prepared with washed and unwashed surimi.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2621.1996.tb14209.x
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  • 4
    Electronic Resource
    Electronic Resource
    Obliteration of the axillary artery after axillary block (1989)
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 44 (1989), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A case of total obliteration of the axillary artery after axillary block is presented. This resulted from an accidental intramural injection of local anaesthetic (mepivacaine 1%, 40ml, with adrenaline 1:200 000). Axillary block was performed using the loss of resistance technique with a blunt needle (45° bevel). The diagnosis was made by paplation of the peripheral pluse and by comparison between the skin temperatures of each arm. The thrombosed part of the artery was successfully reconstructed with an autologous saphenous vein graft.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2044.1989.tb09269.x
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  • 5
    Electronic Resource
    Electronic Resource
    Kontralaterale Synkinesien (1969)
    Springer
    Journal of neurology 195 (1969), S. 187-198 
    Details
    ISSN: 1432-1459
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es wurden 3 Fälle von kongenitalen Spiegelsynkinesien bei neurologisch sonst völlig unauffälligen Patienten, ein klinisch stummer Fall einer idiopathischen Spiegelsynkinesie sowie 13 Fälle von kontralateralen Synkinesien infolge Pyramidenbahnläsionen bei intrakraniellen Tumoren klinisch und elektromyographisch untersucht und verglichen. Auf Grund der Verschiedenheit in der Art der induzierten Kontraktionen und in der Latenz, die sich bei aquirierten Synkinesien als bedeutend länger erwies, wird gefolgert, daß die idiopathischen und die symptomatischen, durch Pyramidenbahnläsion ausgelösten Synkinesien klinisch elektromyographisch und pathogenetisch prinzipiell von einander zu trennen sind. Bei den symptomatischen Synkinesien wird eine polysynaptische Impulsübertragung im Bereich der motorischen Reticularformation angenommen, während den idiopathischen Synkinesien eine cortico-spinale Entstehung zugeschrieben wird.
    Notes: Summary Three patients with congenital symmetrical synkinesis without other neurological symptoms, one patient with idiopathic symmetrical synkinesis without any clinical symptoms at all, and 13 other patients with contralateral synkinesis due to pyramidal tract lesions accompanying intracranial tumors were examined physically and electromyographically and compared to each other. In view of differences both in the type of induced contractions and in the latencies — the latter being much longer in the acquired forms — it is concluded that the symptomatic synkineses due to lesions of the pyramidal tracts are to be distinguished from the idiopathic ones in clinical, electromyographical and pathogenetic terms. For the symptomatic synkineses a polysynaptic transmission at the level of the motor reticular formation is assumed while the idiopathic forms are considered to be of corticospinal origin.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00242467
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Bacteremia after cholangiography (1982)
    Springer
    Digestive diseases and sciences 27 (1982), S. 1145-1146 
    Details
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01391460
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Differing effects of ursodeoxycholic or chenodeoxycholic acid on biliary cholesterol saturation and bile acid metabolism in man (1982)
    Springer
    Digestive diseases and sciences 27 (1982), S. 161-168 
    Details
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A dose-response study comparing ursodeoxycholic and chenodeoxycholic acid was carried out in six men with asymptomatic radiolucent gallstones present in well-visualizing gallbladders. The study tested the effects of a low (averaging 6 mg/kg/day) or medium dose (averaging 11 mg/kg/day) of each bile acid on the cholesterol saturation of bile as well as on bile acid metabolism, as inferred from biliary and fecal bile acid composition. Ursodeoxycholic acid, at low or medium doses, induced bile desaturation in most patients, whereas chenodeoxycholic acid did not. Despite the greater desaturation efficacy of ursodeoxycholic acid, biliary bile acids became less enriched with the administered bile acid during ursodeoxycholic acid treatment than during chenodeoxycholic acid treatment. Both bile acids were nearly completely 7-dehydroxylated to lithocholic acid by colonic bacteria, but biliary lithocholic increased only slightly (and similarly) with each bile acid. Fecal bile acid composition suggested that administered ursodeoxycholic acid suppressed endogenous bile acid synthesis much less than chenodeoxycholic acid. The results indicate that ursodeoxycholic acid and chenodeoxycholic acid have similar but not identical effects on bile acid metabolism, but that for a given dose, ursodeoxycholic acid is a more potent desaturating agent than chenodeoxycholic acid. The results suggest that cholesterol gallstone dissolution with ursodeoxycholic acid should occur with a dose of 8–10 mg/kg in most nonobese patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01311711
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