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  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Physics Letters A 48 (1974), S. 51-52 
    ISSN: 0375-9601
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 102 (1980), S. 6642-6644 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1420-908X
    Keywords: Factor XIII ; Wound healing ; Liver injury
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract An involvement of blood coagulation factor XIII (FXIII) in healing of burns was examined in rats with the carbon tetrachloride (CCl4)-induced hepatic injury. The oral administration of 2 and 4 ml/kg CCl4 to rats every 4 days delayed healing of the burns induced on the back skin and decreased FXIII activity. These animals showed some hepatotoxic signs (increased glutamicoxaloacetic and glutamic-pyruvic transaminases) and accelerated blood coagulation system (increased fibrinopeptide A and fibrin degradation product). The delay in the burn healing was shortened by repeated intravenous injections with normal human placenta-derived FXIII concentrate (Fibrogammin P; 120 U/body) every 4 days. There was a negative correlation between plasma FXIII activity at the end of experiment and the time required for wound healing. These findings suggest that reduction in FXIII activity may be one of the factors inducing delayed wound healing in the CCl4-induced hepatic injury rats.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Inflammation research 31 (1990), S. 321-328 
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Leflunomide (HWA 486, a novel isoxazol derivative), shown to have potent immunosuppressant and antiinflammatory effects, was evaluated for its inhibitory and therapeutic effects on the glomerulonephritis induced in rats by rabbit antiserum against rat glomerular basement membrane. Leflunomide was administered orally to rats at 0.5 and 2 mg/kg/day for 20 days from 2 days before injection of the rabbit antiserum and at 2 mg/kg/day for 14 days from 5 days after the antibody injection. The present study consisting of 2 experiments for inhibitory (I) and therapeutic (II) effects of leflunomide revealed the following effects at 2 mg/kg: in experiment I, significant decreases in (a) urinary total protein, (b) plasma total cholesterol and fibrinogen and (c) thymus weight, and decreased incidences of fibrin deposits in Bowman's space, adhesion of the glomerulus to Bowman's capsule and deposition of rat IgG and C3; and in experiment II, decreases in (a), (b) and (c), though smaller than in experiment I, and decreases deposition of rat C3. Thus, leflunomide had potent inhibitory and limited therapeutic effects on glomerulonephritis, suggesting that the compound is effective in inhibiting the onset and development of glomerulonephritis.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 44 (1988), S. 768-771 
    ISSN: 1420-9071
    Keywords: Spasmin-like proteins ; Carchesium ; Vorticella ; Stentor ; Spirostomum ; Blepharisma ; immunoblotting
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary It was found that some ciliates,Stentor, Spirostomum andBlepharisma, which can contract rapidly like the stalks of Vorticellidae, have Ca2+-binding proteins that are very similar to spasmins, in the immunological sense. The presence of spasmins in other Protozoa and in some Metazoa was also investigated.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Lung 87 (1935), S. 64-74 
    ISSN: 1432-1750
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung 1. Bacillämie bei Tuberkulose tritt nicht chronisch, sondern schubweise auf. 2. Im frühen Stadium der Tuberkuloseinfektion ist Bacillämie häufig nachweisbar. 3. Bei Kranken mit Pleuritis exsudativa, Frühinfiltrat und mittelschwerer Lungentuberkulose ist keine Bacillämie nachgewiesen worden. 4. Bei den Fällen, deren Röntgenbild hämatogene Streuung zeigt, wurde Bacillämie häufig nachwewiesen, auch bei Fällen mit extrapulmonaler Tuberkulose. 5. Im Endstadium der schweren Lungentuberkulose und Meningitis tuberculosa ist Bacillämie sehr häufig nachweisbar. 6. Die Bacillämie hat eine gewisse Beziehung zur Tuberkuloseallergie, sie tritt bei negativer oder schwacher Allergie auf.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 116 (1997), S. 83-96 
    ISSN: 1432-1106
    Keywords: Key words Smooth pursuit ; Adaptation ; Peripheral motion signal ; Topography ; Human
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  The main purpose of the present study was to investigate adaptive properties in human smooth-pursuit eye movements generated by a peripheral moving target. In adaptation trials, a target appeared in the peripheral visual field and immediately moved away at a constant speed, and a subject made a saccade and postsaccadic pursuit responses to track it. The target speed was, however, changed to a higher or lower constant speed (step-ramp-ramp target motion) at the termination of the saccade. This adaptation paradigm induced adaptive modifications in postsaccadic pursuit responses and our results revealed the following properties of the pursuit adaptation system. Topographic modification: Modification of the initial pursuit velocity depends on the position of a moving target. Pursuit gain change: Pursuit velocity is modified not by the addition of a constant bias to the pre-adaptation pursuit velocity, but by a change in the pursuit gain (pursuit velocity/target velocity). Lack of influence on saccade properties: Pursuit adaptation does not change the amplitude and latency of saccades either to a moving target or to a stationary target.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 0942-0940
    Keywords: Gliomas ; gray matter ; positron emission tomography (PET) ; radiochemotherapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Haemocirculatory and metabolic changes in seemingly normal brain tissue following radiochemotherapy including nimustine hydrochloride (ACNU) and tegafur (FT) were analyzed using oxygen-15 and fluorine-18 positron emission tomography (PET) in seven patients with gliomas. At an early stage (within one month) after radiochemotherapy, marginal increases in regional cerebral blood flow (rCBF) and cerebral blood volume (rCBV) were found contralateral to the tumour in gray matter which was apparently normal brain structure, as seen on computerized tomography (CT). The oxygen extraction fraction (rOEF) decreased significantly (p 〈 0.05 by a paired-t test) from that of the pretreatment study, due to surgical decompression and radiochemotherapy. At the late stage (three to thirty-one months with a mean of thirteen months), rCBF decreased significantly from the early stage study (p〈0.05); oxygen consumption (rCMRO2) fell in all cases significantly from the pretreatment study (p〈0.01) and from the early stage study (p〈0.05); consequently, rOEF remained unchanged at a level similar to the early stage study. Glucose consumption (rCMRGl) increased slightly as compared with the early stage study but failed to be restored to the level of the pretreatment study. Noteworthy was a coupling reduction of rCBF and rCMRO2—presumably, a late delayed effect of radiochemotherapy. These preliminary results indicate that with PET studies it may be possible to predict damage to normal brain tissue after radiochemotherapy.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 139 (1997), S. 480-481 
    ISSN: 0942-0940
    Keywords: Ophthalmic artery ; arterial anomaly ; angiography ; cerebral aneurysm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Annales geophysicae 14 (1997), S. 1454-1461 
    ISSN: 0992-7689
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract We briefly overview the radar observations that have been made for 30 years at Syowa Station, Antarctica for studying small-scale electron-density irregularities in the southern high-latitude E- and F-region ionosphere. Some observational results (i.e., long-term variations of radio aurora, Doppler spectra with narrow spectral widths and low Doppler velocities, and simultaneous observations of radar and optical auroras) from VHP radars capable of detecting 1.3- to 3-m scale irregularities are presented. A new 50-MHz radar system equipped with phased-antenna arrays began operation in February 1995 to observe two-dimensional behaviors of E-region irregularities. An HF radar experiment also began in February 1995 to explore decameter-scale E- and F-region irregularities in the auroral zone and polar cap. These two radars will contribute to a better understanding of the ionospheric irregularities and ionospheric physics at southern high latitudes.
    Type of Medium: Electronic Resource
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