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  • 1
    Digitale Medien
    Digitale Medien
    Mapping of theHox-3.1 andMyc-1.2 genes on chromosome 15 of the mouse by restriction fragment length variations (1990)
    Springer
    Biochemical genetics 28 (1990), S. 257-266 
    Details
    ISSN: 1573-4927
    Schlagwort(e): mice ; subspecies ; homeo box ; c-myc oncogene ; linkage test ; restriction fragment length variation (RFLV)
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie
    Notizen: Abstract Restriction endonuclease fragment length variations (RFLV) were detected by use of the cDNA probeHox-3.1 for the homeo box-3.1 gene and also thec-myc oncogene probe for exon 2. RFLV ofHox-3.1 were found inHindIII restriction patterns, and RFLV of theMyc-1.2 gene inEcoRV patterns. From the RFLV, theHox-3.1 andMyc-1.2 genes were mapped on chromosome 15. Three-point cross test data showed that the frequency of recombination is 26.4% betweenMyc-1.2 andGpt-1, 30.2% betweenGpt-1 andGdc-1, and 9.4% betweenGdc-1 andHox-3.1. The following order of these genes is proposed,Myc-1.2—Gpt-1—Gdc-1—Hox-3.1. All laboratory strains carry theHox-3.1 a andMyc-1.2 a alleles. Among strains of wild origin,domesticus strains carry only theHox-3.1 a andMyc-1.2 a alleles, as do the laboratory strains. One strain ofbrevirostris carries theHox-3.1 a andMyc-1.2 b alleles. Other wild subspecies from Europe and Asia,M. m. musculus, M. m. castaneus, M. m. molossinus, Chinese mice of wild origin, andM. m. yamashinai carry theHox-3.1 b andMyc-1.2 b alleles.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00554083
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  • 2
    Digitale Medien
    Digitale Medien
    Restriction fragment length variations and chromosome mapping of two mouse metallothionein genes,Mt-1 andMt-2 (1989)
    Springer
    Biochemical genetics 27 (1989), S. 689-697 
    Details
    ISSN: 1573-4927
    Schlagwort(e): restriction fragment length variation ; metallothionein ; chromosome mapping
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie
    Notizen: Abstract Restriction endonuclease fragment length variations (RFLVs) were found through the use of cDNA probes for metallothionein genes 1 (Mt-1) and 2 (Mt-2) in the mouse. RFLVs were detected in restriction patterns generated byBglII andXbaI in theMt-1 gene and byPvuII in theMt-2 gene. All laboratory strains carry theMt-1 a andMt-2 a alleles. Among strains of wild origin, some Western European subspecies (Mus mus domesticus andM. m. brevirostris) also carry theMt-1 a andMt-2 a alleles. In contrast, a European subspecies (M. m. musculus) and the great majority of subspecies from East Asian countries (M. m. molossinus, Chinese mice of wild origin, andM. m. yamashinai) carry theMt-1 b andMt-2 b alleles. Adomesticus strain from Bulgaria and twocastaneus strains from Thailand and Philippines carry the intermediate combination ofMt-1 b andMt-2 a alleles. Using the RFLVs, we mapped theMt-1 andMt-2 genes on chromosome 8, and they appear to be very closely linked since no recombination was observed between them in any of the mice examined. Data from three-point cross tests showed that the recombination frequencies are 4.31% betweenOs andMt, 15.52% betweenMt andPrt-2, and 19.83% betweenOs andPrt-2. The gene order ofOs-Mt-1,Mt-2-Prt-2 has been confirmed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00553990
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  • 3
    Digitale Medien
    Digitale Medien
    Restriction fragment length variations and chromosome mapping of two mouse metallothionein genes,Mt-1 andMt-2 (1989)
    Springer
    Biochemical genetics 27 (1989), S. 689-697 
    Details
    ISSN: 1573-4927
    Schlagwort(e): restriction fragment length variation ; metallothionein ; chromosome mapping
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie
    Notizen: Abstract Restriction endonuclease fragment length variations (RFLVs) were found through the use of cDNA probes for metallothionein genes 1 (Mt-1) and 2 (Mt-2) in the mouse. RFLVs were detected in restriction patterns generated byBglII andXbaI in theMt-1 gene and byPvuII in theMt-2 gene. All laboratory strains carry theMt-1 a andMt-2 a alleles. Among strains of wild origin, some Western European subspecies (Mus mus domesticus andM. m. brevirostris) also carry theMt-1 a andMt-2 a alleles. In contrast, a European subspecies (M. m. musculus) and the great majority of subspecies from East Asian countries (M. m. molossinus, Chinese mice of wild origin, andM. m. yamashinai) carry theMt-1 b andMt-2 b alleles. Adomesticus strain from Bulgaria and twocastaneus strains from Thailand and Philippines carry the intermediate combination ofMt-1 b andMt-2 a alleles. Using the RFLVs, we mapped theMt-1 andMt-2 genes on chromosome 8, and they appear to be very closely linked since no recombination was observed between them in any of the mice examined. Data from three-point cross tests showed that the recombination frequencies are 4.31% betweenOs andMt, 15.52% betweenMt andPrt-2, and 19.83% betweenOs andPrt-2. The gene order ofOs-Mt-1,Mt-2-Prt-2 has been confirmed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02396061
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  • 4
    Digitale Medien
    Digitale Medien
    A molecular genetic linkage map of mouse chromosome 18, includingspm, Grl-1, Fim-2/c-fms, andMbp (1991)
    Springer
    Biochemical genetics 29 (1991), S. 103-113 
    Details
    ISSN: 1573-4927
    Schlagwort(e): mice ; subspecies ; sphingomyelinosis ; glucocorticoid receptor ; Friend MuLV integration site ; myelin basic protein ; linkage test ; restriction fragment length variations (RFLV)
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie
    Notizen: Abstract Restriction endonuclease fragment length variations (RFLV) were detected in mice with DNA probes for myelin basic protein (Mbp), glucocorticoid receptor-1 (Grl-1), and Friend MuLV integration site-2 (Fim-2). RFLV of theMbp gene were found inSacI restriction patterns, RFLV of theGrl-1 gene were found inEcoRV patterns, and RFLV of theFim-2 were found inBglII patterns. A three-point backcross was carried out by the backcross mating (C57BL/KsJ-spm/spm × MOL-MIT)F1 males × C57BL/KsJ-spm/spm; spm is an autosomal recessive gene causing sphingomyelinosis. From the results,spm, Grl-1, Fim-2, andMbp loci were mapped on chromosome 18, and the following order of genes is proposed, with distances between genes in parentheses: centromere—spm—(7.8 cM)—Grl-1—(7.8 cM)—Fim-2—(39.1 cM)—Mbp—telomere. All laboratory strains and two European subspecies (Mus mus domesticus andM. m. brevirostris) carry theGrl-1 a ,Fim-2 a , andMbp a alleles. In contrast, another wild subspecies from Europe (M. m. musculus) and some Asian subspecies (M. m. molossinus, Chinese mice of wild origin, andM. m. yamashinai) carry theGrl-1 b ,Fim-2 b , andMbp b alleles. Onlycastaneus strains carry the intermediate combination of theGrl-1 b ,Fim-2 a , andMbp b alleles.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00578243
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  • 5
    Digitale Medien
    Digitale Medien
    Mapping of theHox-3.1 andMyc-1.2 genes on chromosome 15 of the mouse by restriction fragment length variations (1990)
    Springer
    Biochemical genetics 28 (1990), S. 257-266 
    Details
    ISSN: 1573-4927
    Schlagwort(e): mice ; subspecies ; homeo box ; c-myc oncogene ; linkage test ; restriction fragment length variation (RFLV)
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie
    Notizen: Abstract Restriction endonuclease fragment length variations (RFLV) were detected by use of the cDNA probeHox-3.1 for the homeo box-3.1 gene and also thec-myc oncogene probe for exon 2. RFLV ofHox-3.1 were found inHindIII restriction patterns, and RFLV of theMyc-1.2 gene inEcoRV patterns. From the RFLV, theHox-3.1 andMyc-1.2 genes were mapped on chromosome 15. Three-point cross test data showed that the frequency of recombination is 26.4% betweenMyc-1.2 andGpt-1, 30.2% betweenGpt-1 andGdc-1, and 9.4% betweenGdc-1 andHox-3.1. The following order of these genes is proposed,Myc-1.2—Gpt-1—Gdc-1—Hox-3.1. All laboratory strains carry theHox-3.1 a andMyc-1.2 a alleles. Among strains of wild origin,domesticus strains carry only theHox-3.1 a andMyc-1.2 a alleles, as do the laboratory strains. One strain ofbrevirostris carries theHox-3.1 a andMyc-1.2 b alleles. Other wild subspecies from Europe and Asia,M. m. musculus, M. m. castaneus, M. m. molossinus, Chinese mice of wild origin, andM. m. yamashinai carry theHox-3.1 b andMyc-1.2 b alleles.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02401416
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  • 6
    Digitale Medien
    Digitale Medien
    A molecular genetic linkage map of mouse chromosome 10, including theMyb, S100b, Pah, Sl, andIfg genes (1992)
    Springer
    Biochemical genetics 30 (1992), S. 529-535 
    Details
    ISSN: 1573-4927
    Schlagwort(e): mouse ; subspecies ; Sl gene ; linkage test ; restriction fragment length variation (RFLV)
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie
    Notizen: Abstract Restriction endonuclease fragment length variations (RFLV) on mouse chromosome 10 were detected in four genes, namely, theMyb protooncogene (Myb) and the genes for S100β protein (S100b), phenylalanine hydroxylase (Pah), and interferon-γ (Ifg). RFLV were found in restriction patterns generated withBamHI forMyb, in those generated withBglII forS100b, in those generated withEcoRV forPah, and in those generated withTaqI forIfg. A multipoint backcross was carried out by the mating (129/Sv-Sl/+ × MOL-MIT)F1 × 129/SvJ-+/+. TheSl mutation has phenotypic effects which include deficiencies in pigment cells, germ cells, and blood cells. The following order of genes was derived from the results of the multipoint backcross, with distances between genes in parentheses: centromere—Myb—(34.9 cM)—S100b—(8.5 cM)—Pah—(8.5 cM)—Sl—(12.3 cM)—Ifg—telomere. Most laboratory strains and two strains ofMus musculus domesticus of wild origin carry theMyb a, S100a, Paha, andIfg a alleles. In contrast, a strain ofM. m. musculus, two strains ofM. m. yamashinai, and two strains ofM. m. molossinus carry theMyb b, S100b, Pahb, andIfg b alleles. Other strains of wild origin carry various combinations of these alleles.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01037591
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  • 7
    Digitale Medien
    Digitale Medien
    A molecular genetic linkage map of mouse chromosome 19, including thelpr, Ly-44, andTdt genes (1991)
    Springer
    Biochemical genetics 29 (1991), S. 325-335 
    Details
    ISSN: 1573-4927
    Schlagwort(e): mouse ; subspecies ; lpr gene ; autoimmune disease ; linkage test ; restriction fragment length variations (RFLV)
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie
    Notizen: Abstract The mouselpr gene, which is an autosomal recessive gene causing autoimmune disease with features of human systemic lupus erythematosus and eventually death from severe immune-complex glomerulonephritis, has been mapped on chromosome 19. To determine its exact chromosomal location, a three-point backcross was carried out by mating (MRL/MpJ-lpr/lpr × MOL-MIT)F1 × MRL/MpJ-lpr/lpr using the genesLy-44 (lymphocyte differentiation antigen-44) andTdt (terminal deoxynucleotidyl transferase) as markers. The following order of genes is proposed, with the distances between genes given in parentheses: centromere-Ly-44 (19.3 cM)-lpr (6.1 cM)-Tdt-telomere. TheLy-44 a andTdt a alleles are found in all laboratory strains and in the wild Western European subspecies,domesticus andbrevirostris. In contrast, theLy-44 b andTdt b alleles are found in some Asian subspecies, Chinese mice of wild origin,yamashinai andmolossinus. Furthermore the thirdTdt allele,Tdt c , is detected incastaneus.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00554140
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  • 8
    Digitale Medien
    Digitale Medien
    A new allele at the lpr gene on mouse Chromosome 19 expresses properties different from the original recessive mutation (1993)
    Springer
    Mammalian genome 4 (1993), S. 346-347 
    Details
    ISSN: 1432-1777
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00357096
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  • 9
    Digitale Medien
    Digitale Medien
    Assimilation of liquid hydrocarbon by microorganisms. II. Growth kinetics (1977)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 19 (1977), S. 715-726 
    Details
    ISSN: 0006-3592
    Schlagwort(e): Chemistry ; Biochemistry and Biotechnology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: The growth kinetics of a microorganism with high affinity for liquid hydrocarbon which has a low solubility in water was investigated for Candida intermedia IFO 0761 in our previous work.6 The microorganism contained a hydrocarbon pool in and/or on the cell. The transfer of water-soluble substrates to the cell was not the rate-limiting step in the growth of C. intermedia accompanied by clump formation with liquid hydrocarbon. The operating conditions necessary for the oxygen supply for the growth were adequate for the growth of C. intermedia on n-tetradecane. The saturation kinetics was valid for the specific growth rate of C. intermedia and specific concentration of hydrocarbon per unit cell mass; the specific growth rate was expressed by the following equation: \documentclass{article}\pagestyle{empty}\begin{document}$$\mu = \frac{{\mu _{\max} \; {S \mathord{\left/ {\vphantom {S X}} \right. \kern-\nulldelimiterspace} X}}}{{K_S + {S \mathord{\left/ {\vphantom {S X}} \right. \kern-\nulldelimiterspace} X}}} $$\end{document}
    Zusätzliches Material: 17 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bit.260190508
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