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  • 1
    Digitale Medien
    Digitale Medien
    Charcot-Marie-Tooth disease: study of a large kinship with an intermediate form (1985)
    Springer
    Journal of neurology 232 (1985), S. 91-98 
    Details
    ISSN: 1432-1459
    Schlagwort(e): Charcot-Marie-Tooth disease ; Intermediate form
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary A clinical, genetic, electrophysiological and ultrastructural study of a large kinship with peroneal muscular atrophy is reported. There was a noteworthy homogeneity in the phenotype as well as in the electrophysiological characteristics encountered in 15 affected members aged between 7 and 72 years. The symptoms appeared first in the second decade of life and stabilized by the fourth decade. There was no evidence of linkage of the neuropathy gene to the Duffy blood group locus on chromosome 1. The electrophysiological data in this family as well as the ultrastructural findings confirm that there is heterogeneity in hereditary motor and sensory neuropathy type I, and support the concept of an intermediate form of Charcot-Marie-Tooth disease.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00313907
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  • 2
    Digitale Medien
    Digitale Medien
    Diagnostic specificity of sensory and motor nerve conduction variables in early detection of carpal tunnel syndrome (1989)
    Springer
    Journal of neurology 236 (1989), S. 208-213 
    Details
    ISSN: 1432-1459
    Schlagwort(e): Carpal tunnel syndrome ; Neural conduction ; Median nerve ; Ulnar nerve ; Radial nerve
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary In the carpal tunnel syndrome (CTS) sensory nerve conduction is more sensitive than motor conduction. However, 8%–25% of the sensory distal latencies in symptomatic hands may still be normal. A systematic study was made of the median, ulnar and radial orthodromic nerve conduction velocities (SNCV) stimulating each of the fingers separately. Four SNCVs from the median nerve, two SNCVs from the ulnar nerve and one from the radial nerve were obtained, and the ratio of the median to radial SNCV and the ratios of the median and ulnar SNCVs were estimated. The significance of these parameters in the diagnosis of the CTS was studied, and a rapid technique for the screening of nerve entrapment in the initial stages of the disease is proposed. Three hundred and seventy-five symptomatic hands were examined. Seventy-five hands showed normal distal latency, in which cases, however, the SNCV of the ring finger was always outside the normal range, while the SNCVs of the thumb, index and middle fingers were abnormal in 64%, 80% and 92% of cases respectively. The amplitudes of the sensory responses were the least sensitive of the parameters studied. Our results suggest that a study of the median nerve digital branch to the ring finger may be of value in providing an easily performed and rapid technique for screening an early median nerve entrapment at the wrist.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00314501
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  • 3
    Digitale Medien
    Digitale Medien
    Toxic polyneuropathy of shoe workers in Italy. A clinical, neurophysiological and follow-up study (1983)
    Springer
    Neurological sciences 4 (1983), S. 463-472 
    Details
    ISSN: 1590-3478
    Schlagwort(e): Shoe-makers' polyneuropathy ; neurotoxic solvents ; n-hexane polyneuropathy
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Sommario Sono stati studiati numerosi casi di polineuropatia dovuta ad esposizione professionale a solventi industriali in diversi calzaturifici della provincia di Siena. Lo screening di 654 lavoratori ha permesso di identificare 98 casi di polineurite, di cui 16 gravi, 45 di media gravità e 37 senza sintomi neurologici obiettivi ma con le caratteristiche alterazioni elettrodiagnostiche. La studio longitudinale di 53 pazienti ha dimostrato che la sintomatologia neurologica sia soggettiva che obiettiva cosi come le alterazioni elettrodiagnostiche continuano per anni in numerosi pazienti. Inoltre, dopo alcuni anni di osservazione, alcuni pazienti mostrano segni di interessamento del SNC come spasticità ed iperreflessia. In tutti i campioni di colle e di solventi utilizzati sia dai lavoratori a domicilio sia nelle fabbriche dove si sono verificati casi di polineurite, è stata trovata un'alta percentuale di esano commerciale.
    Notizen: Abstract Cases of polyneuropathy due to exposure to industrial solvents have been studied at several shoe factories in the province of Siena. After the screening of 654 employees 98 verified cases were detected. Of these, 16 were rated as moderate to severe, 45 as mild, and 37 were minimally involved but with characteristic electrodiagnostic abnormalities. Follow-up study in 53 patients showed that neurological signs and symptoms as well as electrodiagnostic abnormalities continued for years in several patients. In addition, after a year's observation, some patients showed signs of central nervous system dysfunction such as spasticity of the lower limbs and increased deep tendon reflexes. High percentages of commercial n-hexane were found in all the samples of glues and solvents collected from home-workers and from factories where cases of polyneuropathy occurred.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02125628
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  • 4
    Digitale Medien
    Digitale Medien
    Altered CSF protein pattern in a case of mycosis fungoides with nervous system involvement (1986)
    Springer
    Neurological sciences 7 (1986), S. 89-92 
    Details
    ISSN: 1590-3478
    Schlagwort(e): Mycosis fungoides (MF) ; CSF proteins ; immunosuppressive therapy
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Sommario Si riporta lo studio clinico, neurofisiologico e liquorale in un caso di M.F. con interessamento del Sistema Nervoso. Nel liquor della paziente è stata identificata una proteina anomala del p.m. di 22.000, assente nel siero della paziente e nel liquor di soggetti di controllo, scomparsa dopo terapia immunosoppressiva endorachide. La natura di questa proteina è discussa alla luce delle ipotesi patogenetiche della malattia.
    Notizen: Abstract We report the clinical, neurophysiological and CSF study in a case of mycosis fungoides with nervous system involvement. The CSF contained an abnormal protein of molecular weight 22000 that was not in the patient's serum or in the CSF of control subjects and that disappeared after intrathecal immunosuppressive therapy. The nature of this protein is discussed in the light of hypotheses regarding the pathogenesis of the disease.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02230423
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  • 5
    Digitale Medien
    Digitale Medien
    Cervical myelopathy secondary to ossification of the posterior longitudinal ligament (a case report) (1984)
    Springer
    Neurological sciences 5 (1984), S. 203-207 
    Details
    ISSN: 1590-3478
    Schlagwort(e): Cervical myelopathy ; longitudinal ligament ossification
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Sommario Viene riportato un caso di ossificazione del legamento longitudinale posteriore, documentato con Rx, mielografia e TAC della colonna vertebrale. Il paziente è stato sottoposto a laminectomia decompressiva per via posteriore, con miglioramento della sintomatologia. II caso viene discusso alla luce degli altri dati della letteratura.
    Notizen: Abstract A case of ossification of the posterior longitudinal ligament, documented by spinal X-ray, myelography and CT scanning of the spinal cord is reported. The patient underwent decompressive laminectomy by posterior approach, which was successful. The case is discussed in the light of recent published data.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02043224
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  • 6
    Digitale Medien
    Digitale Medien
    Familial lead poisoning from contaminated wine (1981)
    Springer
    Neurological sciences 2 (1981), S. 283-290 
    Details
    ISSN: 1590-3478
    Schlagwort(e): Lead intoxication
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Sommario Tre componenti di una famiglia hanno sofferto di una intossicazione da piombo di origine industriale da vino prodotto in casa e lasciato fermentare in recipienti di terracotta smaltata. Le caratteristiche cliniche ed elettrofisiologiche dei casi vengono descritti in rapporto con casi analoghi citati dalla letteratura. La diagnosi corretta e il precoce trattamento di queste polineuropatie da piombo non industriale risultano spesso difficili per la natura occasionale dell' azione tossica.
    Notizen: Abstract Three members of a family were found be suffering from lead poisoning of nonindustrial origin, the causative agent being the home-produced wine left to ferment in a glazed earthenware vat. The clinical and neurophysiological features are discussed in the light of similar cases in the literature. Correct diagnosis and early treatment of nonindustrial lead polyneuropathy are often extremely difficult because of the elusive nature of the exposure.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02335409
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