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  • 1
    Electronic Resource
    Electronic Resource
    Acute ventilatory restriction in children after weaning off inhaled nitric oxide: relation to rebound pulmonary hypertension (1999)
    Springer
    Intensive care medicine 25 (1999), S. 76-80 
    Details
    ISSN: 1432-1238
    Keywords: Key words Nitric oxide ; Rebound ; Pulmonary hypertension ; Dynamic respiratory system compliance ; Interaction ; Congenital heart disease compliance ; Interaction ; Congenital heart disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective: To assess the interaction between pulmonary hemodynamics and respiratory mechanics during acute pulmonary hypertension. Patients: Ventilated and paralysed children treated with inhaled nitric oxide because of post-operative pulmonary hypertension. Interventions: Weaning of inhaled nitric oxide. Measurements: Air flow and airway pressure, calculation of dynamic respiratory system compliance and respiratory system resistance for each breath by multiple linear regression. Results: In four patients, increases in pulmonary arterial pressure from 26.1 to 56.7 mmg (p 〈 0.001) during weaning off nitric oxide were associated with decreases in tidal volume (from 9.7 → 8.2 ml/kg, p 〈 0.01) and reductions in dynamic respiratory system compliance (from 0.52 → 0.34 cmH20/ml/kg, p 〈 0.001), while respiratory system resistance was unchanged. Conclusions: Impaired ventilation during acute pulmonary hypertension is predominantly related to a reduction in respiratory system compliance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001340050790
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Negative pressure ventilation as haemodynamic rescue following surgery for congenital heart disease (2000)
    Springer
    Intensive care medicine 26 (2000), S. 93-96 
    Details
    ISSN: 1432-1238
    Keywords: Key words Children ; Cardiac output ; Ventilation ; Diastole
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A low cardiac output state is an important cause of morbidity and mortality following repair of tetralogy of Fallot (ToF). This is often refractory to conventional measures. The cardiac output of these patients is highly dependent on diastolic pulmonary arterial flow which is enhanced during spontaneous respiration, but much reduced by intermittent positive pressure ventilation (IPPV).¶We report the successful use of negative pressure ventilation (NPV) as haemodynamic therapy in three children with a low output secondary to restrictive right ventricular (RV) physiology following ToF repair. NPV produced a significant haemodynamic improvement, with increases in cardiac output of greater than 100 % in two of the children. By augmenting pulmonary blood flow, and hence cardiac output, NPV has a role as adjunctive haemodynamic therapy in patients with a low output secondary to diastolic RV dysfunction, in whom early extubation is not possible.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001340050018
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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