ISSN:
1435-4373
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The objective of this study was to investigate the spectrum and frequency of rare AIDS-defining diseases in the Swiss HIV Cohort Study. AIDS-defining diseases contributing less than 1% to the absolute number of all recorded AIDS-defining diseases in at least one of five periods (1988–1990, 1991–1992, 1993–1994, 1995–1996, 1997) were defined as being rare. A total of 9110 HIV-infected subjects were included in this study. Over the entire 9-year period, the following rare diseases were diagnosed: progressive multifocal leukoencephalopathy (n=138), disseminated cryptococcosis (n=67), visceral herpes simplex disease (n=66), primary cerebral lymphoma (n=65), indeterminate cerebral lesion (n=50), cryptococcal meningitis (n=34), Mycobacterium kansasii disease (n=32), recurrent Salmonella septicemia (n=22), intestinal isosporiasis (n=21), candidiasis of the trachea, bronchi and lungs (n=19), toxoplasma retinitis (n=16), disseminated toxoplasmosis (n=8), invasive cervical carcinoma (n=8), extrapulmonary Pneumocystis disease (n=5), disseminated histoplasmosis (n=1) and disseminated coccidioidomycosis (n=1). Rare diseases accounted for 7.3% of all AIDS-defining diseases over the entire 9-year period. Physicians should be aware of the likelihood of a broad spectrum of AIDS-defining diseases in HIV-infected patients.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s100960050307
Permalink
