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  • 1
    Electronic Resource
    Electronic Resource
    THE EFFECTS OF ASPHYXIA ON 5-HYDROXYTRYPTAMINE METABOLISM IN THE IMMATURE RAT BRAIN (1976)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 27 (1976), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Fire-day-old rats subjected to prolonged asphyxia at 37°C show a slower rate of synthesis of 5-HT as measured by the accumulation of the amine after inhibition of monoamine oxidase. During recovery from asphyxia 5-HT synthesis is markedly stimulated when measured over a 50 or 90 min period. No change in 5-HT synthesis was observed in 5-day-old rats during recovery from cold exposure or immobilization. The results indicate that the persistent increase in synthesis that follows resuscitation may be related to asphyxia per se rather than to the stress component of the treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1976.tb00330.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    TRYPTOPHAN AND 5-HYDROXYTRYPTAMINE METABOLISM IN THE IMMATURE RAT BRAIN DURING RECOVERY FROM ASPHYXIA (1977)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 28 (1977), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract— The turnover of cerebral 5-HT in the 5-day-old rat during recovery from asphyxia was assessed in the brain by determining 5-hydroxyindoleacetic acid concentration, and by following the accumulation of 5-HT after inhibition of MAO. Marked increases in turnover were found to persist for up to 3 h after resuscitation and this increase was accompanied by increases in brain tryptophan, plasma total tryptophan and the fraction of the plasma total tryptophan that was not bound to albumin. None of these parameters were different from those in control animals 24 h after resuscitation. Brain and plasma tyrosine levels remained unaltered by the treatment at all times investigated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1977.tb10436.x
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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