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THE EFFECTS OF ASPHYXIA ON 5-HYDROXYTRYPTAMINE METABOLISM IN THE IMMATURE RAT BRAIN (1976)

Tricklebank, M. D. ; Pickard, F. J. ; Dobbing, J.

Oxford, UK : Blackwell Publishing Ltd

Journal of neurochemistry 27 (1976), S. 0

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ISSN: 1471-4159

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: Fire-day-old rats subjected to prolonged asphyxia at 37°C show a slower rate of synthesis of 5-HT as measured by the accumulation of the amine after inhibition of monoamine oxidase. During recovery from asphyxia 5-HT synthesis is markedly stimulated when measured over a 50 or 90 min period. No change in 5-HT synthesis was observed in 5-day-old rats during recovery from cold exposure or immobilization. The results indicate that the persistent increase in synthesis that follows resuscitation may be related to asphyxia per se rather than to the stress component of the treatment.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1471-4159.1976.tb00330.x

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