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  • 1
    Electronic Resource
    Electronic Resource
    The effect of temporal and force changes on the patterning of sequential movements (1993)
    Springer
    Psychological research 55 (1993), S. 116-123 
    Details
    ISSN: 1430-2772
    Source: Springer Online Journal Archives 1860-2000
    Topics: Psychology
    Notes: Summary This article examines the programming of relatively long sequences of action with the control of sequential movements being effected through the use of a tapping task involving a sequence of five taps. Subjects were required to tap with their right hand at rates of 150, 200, and 250 ms. There were two conditions, with subjects being required either to increase, in condition 1, or to decrease, in condition 2, the force at one of the five tap positions (all five tap positions were examined), then return to the previous force level. Changes in timing resulting from variations in the force characteristics have previously been discussed in terms of changes in the organizational time required ( Semjen, Garcia-Colera, & Requin, 1984). The current study breaks the intertap interval down into two separate components: the contact interval (finger in contact with the key) and the non-contact interval (interval preceding the tap). Although changes in the non-contact interval could be explained in terms of changes in the organizational time required, changes in the contact interval appeared to be a result of the mechanical changes in force.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00419642
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  • 2
    Electronic Resource
    Electronic Resource
    Decompressive craniectomy to treat intracranial hypertension in head injury patients (1999)
    Springer
    Intensive care medicine 25 (1999), S. 1327-1329 
    Details
    ISSN: 1432-1238
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001340051068
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  • 3
    Electronic Resource
    Electronic Resource
    Guidelines for the pre-hospital care of patients with severe head injuries (1998)
    Springer
    Intensive care medicine 24 (1998), S. 1221-1225 
    Details
    ISSN: 1432-1238
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001340050748
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  • 4
    Electronic Resource
    Electronic Resource
    Secondary intraventricular haemorrhage in blunt head trauma (1986)
    Springer
    Acta neurochirurgica 83 (1986), S. 105-107 
    Details
    ISSN: 0942-0940
    Keywords: Intraventricular haemorrhage ; head injury ; computed tomography ; blood coagulation disturbances in fead injuries
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Intraventricular haemorrhage (IVH) has been detected by computed tomography (CT) in 225 patients admitted to our clinic from 1977 to 1985. In 9 patients IVH was caused by trauma. We report two cases in whom IVH occurred after a lucid interval of about 10 hours postinjury. The pathogenesis of traumatic IVH is discussed comparing these cases with a review of the literature.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01402386
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  • 5
    Electronic Resource
    Electronic Resource
    A practical technique for continuous monitoring of cerebral tissue pressure in neurosurgical patients (1987)
    Springer
    Acta neurochirurgica 87 (1987), S. 144-149 
    Details
    ISSN: 0942-0940
    Keywords: Intracranial pressure ; ventricular fluid pressure ; cerebral tissue pressure ; transducer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A new technique for continuous monitoring of cerebral tissue pressure is presented. It is based on a new type of piecoresistive microtransducer with low baseline and temperature drifts. In 7 patients cerebral tissue pressure and ventricular fluid pressure were recorded simultaneously. Comparison of these two different pressures showed extremely good correlation with coefficients always better than 0.95. Due to another type of pulsewave cerebral tissue pressure was constantly 4 to 12 mm Hg lower than ventricular fluid pressure. Routine use of cerebral tissue monitoring in 12 neurosurgical patients with brain tumours postoperatively showed good clinical correlation of cerebral tissue pressure without any additional complications. The authors recommend continuous monitoring of cerebral tissue pressure as a safe and simple method of intracranial pressure monitoring in neurosurgery.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01476066
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  • 6
    Electronic Resource
    Electronic Resource
    Intrahemispheric gradients of brain tissue pressure in patients with brain tumours (1988)
    Springer
    Acta neurochirurgica 93 (1988), S. 129-132 
    Details
    ISSN: 0942-0940
    Keywords: Cerebral tissue pressure ; brain tumours ; postoperative measurement
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The authors report on 14 patients in whom cerebral tissue pressure was recorded after operation for brain tumours. Cerebral tissue pressure was recorded by a 5 French catheter with two microtransducers. The transducers were placed intraoperatively in the wall of the tumour cavity and in a distance of approximately 2.5 cm. Differences between both pressures from 4 to 28 mmHg were observed. They were higher in patients with glioblastomas and meningiomas than in patients with intracranial metastases. In 7 patients proximal tissue pressure was higher than distal. In 4 patients the contrary was observed. Discussing the literature the authors think intrahemispheric changes of brain water content, blood flow, and brain tissue elastance to be responsible for this phenomenon.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01402894
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  • 7
    Electronic Resource
    Electronic Resource
    Partial Recovery of Paraplegia due to Spontaneous Intramedullary Ependyma Haemorrhage (2000)
    Springer
    Acta neurochirurgica 142 (2000), S. 219-220 
    Details
    ISSN: 0942-0940
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007010050028
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  • 8
    Electronic Resource
    Electronic Resource
    Cerebrospinal fluid free amino acids in patients with spinal space—Occupying lesions (1985)
    Springer
    Acta neurochirurgica 78 (1985), S. 43-45 
    Details
    ISSN: 0942-0940
    Keywords: Free amino acids ; cerebrospinal fluid ; myelopathy ; radiculopathy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 18 different free amino acids were determined in the cerebrospinal fluid of 28 patients with various spinal space—occupying lesions. The study group included 15 patients with lumbar disc lesions (control group), 8 patients with cervical radiculopathy, 4 patients with cervical myelopathy, and 1 patient with a thoracic spinal angioma. The values from the control group were in general accord with those previously observed in normal adults of 5 studies of the literature. Comparison of the values in the different subgroups showed normal values of all amino acids in patients with cervical myelopathy, and significantly higher levels of glutamic acid in patients with cervical radiculopathy. In the case of a thoracic spinal angioma however most free amino acids were extremely high. The authors conclude that this may be due to alterations of the spinal metabolism and that determination of free amino acids in CSF of patients with intradural spinal lesions may help to improve preoperative diagnosis in addition to neuroradiological methods.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01809240
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  • 9
    Electronic Resource
    Electronic Resource
    Expression of differentiation and proliferation related proteins in epithelium of prophylactically removed ovaries from women with a hereditary female adnexal cancer predisposition (2003)
    Oxford, UK : Blackwell Science Ltd
    Histopathology 43 (2003), S. 0 
    Details
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Aims:  To investigate the occurrence of preinvasive neoplastic lesions in ovarian surface epithelium and ovarian inclusion cyst epithelium of women with a hereditary predisposition to the development of female adnexal (ovarian and fallopian tube) carcinoma and to assess the expression of differentiation and proliferation related proteins within putative sites of origin of serous ovarian carcinoma, the ovarian surface epithelium and ovarian inclusion cyst epithelium.Methods:  Twenty-one ovaries, prophylactically removed from 11 women predisposed to the development of female adnexal cancer (cases) were compared with 22 ovaries from 11 women without such predisposition (controls). Archival histological specimens were screened for hyperplastic and dysplastic epithelial lesions. In both the ovarian surface and inclusion cyst epithelia, the percentage of cells was determined that stained positively for Ki67, p21, p27, p53, cyclin A, cyclin D1, bcl-2 and the presence of HER-2/neu, oestrogen (ER-α) and progesterone receptors (PR).Results:  No preinvasive neoplastic lesions were detected. However, hyperplastic areas were found in three cases and in four controls (NS). ER-α (P = 0.013), PR (P 〈 0.001), bcl-2 (P = 0.008), p21 (P = 0.046) and p27 (P = 0.008) were expressed in a significantly higher percentage of cells in inclusion cyst epithelium than in ovarian surface epithelium (both groups). The latter showed higher bcl-2 expression in cases (P = 0.05) compared with controls. The inclusion cyst epithelium of cases showed higher expression of bcl-2 (P = 0.006) and PR (P = 0.039) compared with controls. Proliferation was low in both cases and controls as reflected by low Ki67 expression. Over-expression of p53, cyclin D1 and HER-2/neu was not detected.Conclusions:  Premalignant changes are not a common feature of ovaries removed prophylactically from women predisposed to the development of female adnexal carcinoma. Increased expression of p21, p27, and ER-α is seen in inclusion cyst compared with ovarian surface epithelium of women with and without an inherited risk of adnexal carcinoma. This is most probably caused by the different intraovarian hormonal milieu of inclusion cyst epithelium. However, the increased expression of bcl-2 and PR in the inclusion cyst epithelium of patients with a hereditary predisposition may reflect early disruption of hormonal balance and growth control.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2559.2003.01654.x
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  • 10
    Electronic Resource
    Electronic Resource
    The Impaired Control Scale: confirmation of factor structure and psychometric properties for social drinkers and drinkers in alcohol treatment (2002)
    Oxford, UK : Blackwell Science Ltd
    Addiction 97 (2002), S. 0 
    Details
    ISSN: 1360-0443
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Notes: To examine (1) the structure of the Impaired Control Scale using confirmatory factor analytical techniques and (2) the internal consistency and validity of the ICS subscales.〈section xml:id="abs1-3"〉〈title type="main"〉DesignCross-sectional data were collected on alcohol-related variables using standard self-completion scales.〈section xml:id="abs1-4"〉〈title type="main"〉ParticipantsThree hundred and fifty-seven social drinkers (not in alcohol treatment) and 137 treatment drinkers (in alcohol treatment) who acknowledged experiencing impaired control over alcohol intake in the last 6 months. Impaired control was defined as drinking more than intended or more than one thinks one should.〈section xml:id="abs1-5"〉〈title type="main"〉MeasurementsSelf-completion questionnaire consisting of demographic questions, Severity of Alcohol Dependence Data questionnaire (SADD), Impaired Control Scale (ICS) and three questions assessing alcohol consumption from the Alcohol Use Disorders Identification Test (AUDIT).〈section xml:id="abs1-6"〉〈title type="main"〉FindingsThis first confirmatory factor analytical study of the ICS found that all three parts of the ICS were unidimensional for both social and treatment drinkers. These results confirmed previous exploratory principal components analysis findings. The excellent validity and internal consistency of all three parts of the ICS found here also confirmed results of previous research into the scale.〈section xml:id="abs1-7"〉〈title type="main"〉ConclusionsThe confirmation of the structure and psychometric properties of the ICS suggest that the scale is a reliable and valid instrument, with a predictable and stable factor structure, for use with both clinical and non-clinical samples.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1360-0443.2002.00190.x
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