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  • 1
    Electronic Resource
    Electronic Resource
    E×B Wien analyzers (abstract) (1988)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 59 (1988), S. 1738-1738 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: The Wien filter is an E×B deflecting analyzer with the electrostatic field perpendicular to the magnetostatic field. The twofold functions of the Wien filter are as an energy analyzer as well as a mass analyzer. It has very high resolution for paraxial charged particle beams with V=E/B, the Wien velocity. Two Wien filters were built and tested for electrons up to 3.5 keV and protons beams of 200 eV. The performance of the two is compared and appears to have features useful for high-temperature plasma diagnostics including simultaneous measurement of energy and mass spectra and high resolution.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1140097
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    New tilted-poles Wien filter with enhanced performance (1989)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 60 (1989), S. 350-357 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: The Wien filter is an E×B deflecting analyzer with the electrostatic field perpendicular to the magnetostatic field. The twofold functions of the Wien filter are as an energy analyzer as well as a mass analyzer. It has very high resolution for paraxial charged-particle beams with V=E/B, the Wien velocity. Two Wien filters, a tilted-poles Wien filter, and a classical parallel-rectangular-poles Wien filter were built and tested for electrons up to 3.5 keV and protons beams of 200 eV. (The tilted-poles Wien filter is a new diagnostic developed by the authors.) The performance of the two is compared, and the tilted-poles Wien filter has superior resolution to the classical Wien filter. Both Wien filters appear to have features useful for high-temperature plasma diagnostics, including simultaneous measurement of energy and mass spectra, and high resolution.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1140437
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Evidence for Preferential Recombination Events in Normal Human T-Cell Repertoires (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 756 (1995), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1995.tb44486.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Construction of a Superantigen through a Structural Modification of an Inactive Protein (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 756 (1995), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1995.tb44495.x
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  • 5
    Electronic Resource
    Electronic Resource
    Diagnosis of HIV-1 infection by PCR with two primer pairs (1993)
    Springer
    European journal of epidemiology 9 (1993), S. 426-429 
    Details
    ISSN: 1573-7284
    Keywords: HIV-1 ; PCR ; SK38/39 ; SK68/69
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We have used two different primer pairs to assess HIV-1 infection of peripheral blood mononuclear cells (PBMC) by polymerase chain reaction (PCR). The study was carried out on 150 individuals: 50 seronegative individuals without risk behaviours for HIV-1 infection, 50 individuals with risk-behaviours but seronegative for HIV-1 and 50 patients with risk-behaviours who were HIV-1 seropositive. Discordances were found between the two primer pairs (SK38/39; SK68/69) in 3 cases. In the non-risk seronegative group, one specimen was scored positive with only one primer pair (SK38/SK39); all the samples belonging to seropositive individuals were found to be positive for HIV-1 DNA using both primer pairs; in the seronegative at risk group 2 samples were positive with only one primer pair (SK38/SK39), and 4 samples were found positive by both primer pairs (SK38/39 & SK68/69). Our study demonstrates that discrepant results take place with relatively high frequency; we propose that all specimens should be tested twice using at least two different primer pairs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00157401
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  • 6
    Electronic Resource
    Electronic Resource
    Helicobacter pylori seroepidemiology in risk groups (1994)
    Springer
    European journal of epidemiology 10 (1994), S. 299-301 
    Details
    ISSN: 1573-7284
    Keywords: Antibody response ; Curved bacilli ; Gastric pathology ; Helicobacter pylori
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Helicobacter pylori is associated with peptic ulcer and chronic active gastritis. The response to infection can be determined by measuring serum titers of anti-H.pylori antibodies. We compared antibody liters in 612 serum samples from 570 individuals considered at risk forH. pylori infection, 170 of them are control sera from 110 adults and 60 children with no gastric alterations. The study groups were 93 institutionalized mentally handicapped children, 40 heterosexual couples, 101 HIV-sero-positive patients, 86 patients with chronic renal failure and 40 individuals (20 adults and 20 children) with symptoms associated with gastritis or gastro duodenal ulcer disease. In the adult and child control groups, 33.5% and 11.6% of the individuals had circulating anti-H.pylori antibodies. Significantly more adults (80%) and children (75%) with gastric symptoms had detectable circulating antibody titers. Elevated titers were also found in institutionalized children and in adults with renal failure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01719353
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  • 7
    Electronic Resource
    Electronic Resource
    Immune complex p24 antigen: A new prognostic marker in human immunodeficiency virus infection (1994)
    Springer
    Infection 22 (1994), S. 4-7 
    Details
    ISSN: 1439-0973
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung In der asymptomatischen Phase der HIV-Infektion läßt sich das p24 Antigen (p24 Ag) meist nicht nachweisen; dies ist vor allem darauf zurückzuführen, daß es an anti-p24 Antikörper (p24 Ab) gebunden ist und mit ihnen Immunkomplexe bildet. Bei neun anti-HIV-1 positiven, asymptomatischen Patienten (Stadium II nach CDC Kriterien), die mit r-alpha-Interferon behandelt wurden, wurden Verlaufsbeobachtungen (7,5 +/- 0,5 Monate) durchgeführt. Basis- und Abschlußuntersuchungen auf p24 Ag Immunkomplexe (p24 Ag-IC), freies p24 Ag, p24 Ab, CD4 Zellzahlen, β2-Mikroglobulin, Properdin B Faktor und Komplementfraktionen C3 und C4 wurden dabei vorgenommen. In 55,5% der Proben fand sich p24 Ag-IC, in 5,5% freies p24 Ag. Die Beobachtung gleichbleibender oder ansteigender Werte von p24 Ag-IC im Serum hat möglicherweise prognostische Bedeutung. Unserer Ansicht nach kann der p24 Ab nicht als prognostischer Marker eingesetzt werden, wenn nicht zugleich die Bestimmung von p24 Ag-IC erfolgt.
    Notes: Summary p24 antigen (p24 Ag) is usually not found in patients in the asymptomatic phase of HIV infection, mainly because it is bound to anti-p24 antibodies (p24 Ab), with which it forms immune complexes. Nine asymptomatic patients positive for HIV-1 antibodies (stage II CDC criteria) treated with rα-interferon were followed (7.5+/-0.5 months), and a basal and final sample were tested for p24 Ag immune complexes (p24 Ag-IC), free p24 Ag, p24 Ab, CD4 count, β2-microglobulin, properdin B factor, and C3 and C4 complement fractions. p24 Ag-IC was detected in 55.5% of the samples, whereas free p24 Ag was detected in 5.5%. The finding of no change or an increase in p24 Ag-IC serum levels may be considered a prognostic marker. We believe that p24 Ab cannot be used as a prognostic marker unless p24 Ag-IC detection is simultaneously evaluated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01780756
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