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  • 1
    Electronic Resource
    Electronic Resource
    A clinical study of Japanese patients with ulcer induced by low-dose aspirin and other non-steroidal anti-inflammatory drugs (2005)
    Oxford, UK : Blackwell Publishing Ltd
    Alimentary pharmacology & therapeutics 21 (2005), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background : The incidence and severity of non-steroidal anti-inflammatory drugs (NSAIDs)-induced gastro-duodenal ulcer have not been extensively studied in Japan.Aim : We performed a prospective study to clarify NSAIDs-induced gastro-duodenal injury, focusing especially on low-dose aspirin (L-A).Methods : Two hundred and thirty-eight patients with bleeding peptic ulcers admitted to our hospital. History of taking NSAIDs and anti-ulcer drugs was obtained from all patients who underwent endoscopic examinations. The lesion scores of patients taking L-A were classified numerically from zero (no lesion) to five (ulcer).Results : The NSAIDs were associated with 28.2% of hemorrhagic ulcers. The rates of patients using L-A, loxoprofen, diclofenac, and combination of two of these drugs were 27, 16, 10 and 9%, respectively. Co-administered anti-ulcer drugs were cytoprotective anti-ulcer drugs (27%), H2 receptor antagonists (16%), PPI (4%), and none (53%). In patients taking L-A, H2 receptor antagonists were used most frequently. The HP was positive in 63% of L-A-induced ulcer cases and in 69% of NSAIDs other than low-dose aspirin-induced ulcer cases. The lesion scores of patients taking L-A with H2 receptor antagonists or PPI were significantly lower than those of patients who were taking only L-A (P 〈 0.05).Conclusions : Approximately one-third of hospitalized patients with NSAIDs-induced hemorrhagic ulcer showed an association with L-A. Prospective randomized controlled trials including H2 receptor antagonists are required to establish preventive efforts aimed at L-A-induced gastro-duodenal injury.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2036.2005.02476.x
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  • 2
    Electronic Resource
    Electronic Resource
    Medical importance of measles in U.A.R. (Egypt) (1965)
    Springer
    Archives of virology 16 (1965), S. 49-52 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary and conclusions Measles in Egypt, as in most parts of the world, is an endemic disease with biennial epidemic waves, which affects mainly children under 3 years of age. The epidemic waves appear mainly at the end of winter and in the spring. From the statistical data available, there is a high ease fatality rate, which is mainly due to the marked under reporting of measles cases, and at the same time a nearly full reporting on the mortality cases due to measles. The real case fatality rate does not exceed 1/10 of this apparent high case fatality rate. In spite of this fact, measles still ranks among the most important causes of childhood morbidity and mortality. As a cause of death among all acute communicable diseases, measles accounted for 17.4 to 23.5% of the deaths in the years 1958 to 1961. Certainly the rapid extension of all medical services and Child Welfare Centers all over Egypt has caused a marked drop in the case fatality rate in the last few years, yet a potent effective vaccine against measles is needed to reduce mortality rates in children to a minimum level.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01253791
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  • 3
    Electronic Resource
    Electronic Resource
    Reutilization by maternal and embryonal cells of nuclear materials from H3-thymidine labeled lymphocytes introduced into the lumen of intestine of rats (1967)
    Springer
    Cell & tissue research 83 (1967), S. 359-363 
    Details
    ISSN: 1432-0878
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary H3-thymidine labeled lymphocytes from thymus and lymph nodes of donor rats were washed and injected in to the intestine of recipient rats on the 11th and 19th day of gestation; subsequent labeling of maternal and embryonal cells was studied autoradiographically 24 hours after injection. In 12-day embryos, numerous stem cells or hemocytoblasts were labeled frequently intensely. In 20-day embryos, stem cells or hemocytoblasts scattered throughout the liver were often labeled. In other fetal tissues at this stage, cells in thymus, spleen, mesenteric lymph node and intestine were labeled but scarcely and weakly. In mothers, labeling in lymphoid tissues was scarce but definite, in thymus, mesenteric lymph node and spleen. These results suggest that nuclear materials from lymphocytes emigrated into the intestinal canal of the mother could be reutilized by maternal and embryonal cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00336864
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