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Analysis of Peg1/Mest imprinting in the mouse (1998)

Reule, M. ; Krause, R. ; Hemberger, M. ; [et al.]

Springer

Development genes and evolution 208 (1998), S. 161-163

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ISSN: 1432-041X

Keywords: Key words Peg1/Mest ; Genomic imprinting ; Mouse

Source: Springer Online Journal Archives 1860-2000

Topics: Biology

Notes: Abstract In the mouse, Peg1/Mest is widely expressed in mesoderm-derived tissues. In separate studies, it has been shown to be maternally imprinted, that is, only the paternally inherited allele is active in mice and in humans. Here, we provide evidence that Peg1/Mest is expressed at very low levels in all tissues of adult mice as assessed by RT-PCR. Moreover, by using species-specific polymorphisms in the Peg1/Mest sequence we can demonstrate that in adult mice the gene remains imprinted in all of these tissues.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/s004270050168

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