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  • 1
    ISSN: 1619-7089
    Keywords: Brain atlas ; Warping ; Emission tomography ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract An elastic computerized brain atlas was developed for the analysis of positron emission tomography/single-photon emission tomography (PET/SPET) data. It consists of a set of digital anatomical contours and a template of regions of interest, schematically describing the brain, derived from a currently used anatomical/functional brain atlas. A warping algorithm, matching equivalent contours, was implemented to elastically fit the atlas to individual brain images. The elastic computerized brain atlas was applied to representative magnetic resonance imaging (MRI)-PET/SPET studies, MRI providing the anatomical information used by the matching procedure. The atlas is suited for clinical use in a nuclear medicine environment.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1619-7089
    Keywords: Positron emission tomography ; Attenuation correction ; Brain
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A hybrid method for attenuation correction (HAC) in positron emission tomography (PET) brain studies is proposed. The technique requires the acquisition of two short (1 min) transmission scans immediately before or after the emission study, with the patient and the head fixation system in place and after removing the patient from the scanner with the head fixation system alone. The method combines a uniform map of attenuation coefficients for the patient's head with measured attenuation coefficients for the head fixation system to generate a hybrid attenuation map. The HAC method was calibrated on 30 PET cerebral studies for comparison with the conventional measured attenuation correction method by ROI analysis. Average differences of less than 3% were found for cortical and subcortical regions. The HAC technique is particularly suitable in a PET clinical environment, allowing a reduction of the total study time, greater comfort for patients and an increase in patient throughput.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1619-7089
    Keywords: Echocardiography ; Positron emission tomography ; Fluorine-18-fluoro-2-deoxy-d-glucose ; Registration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A method has been developed to match corresponding heart regions from functional echocardiographic (Echo) and metabolic fluorine-l8-fluoro-2-deoxy-d-glucose ([18F]FDG) positron emission tomography (PET) studies in individual patients. Echo and PET images are spatially correlated by determining homologous anatomical landmarks (the two papillary muscles and the inferior junction of the right ventricle), identifiable in images obtained by both acquisition modalities. Echo-PET image registration is first performed in the plane identified by the three landmarks, using a rigid rotate-translate scale model. The registration parameters are then used to transform the whole PET volume. This allows a consistent Echo-PET regional analysis, according to a segmental subdivision of the heart. The technique was tested on patients. The overlay of Echo and PET registered images proved the reliability of realignment of the three markers and a good spatial correlation of myocardial walls. This approach to image registration could be applied to other acquisition modalities (such as magnetic resonance imaging and single-photon emission tomography), provided that the three anatomical landmarks are visualized.
    Type of Medium: Electronic Resource
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