Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Letale cerebrale Massenblutung als Erstmanifestation unreifzelliger kindlicher Leukosen (1977)
    Springer
    Acta neuropathologica 38 (1977), S. 233-238 
    Details
    ISSN: 1432-0533
    Keywords: Blast crisis ; Cerebral apoplexy ; First manifestion-hyperleukocytosis ; Immature leukemia ; Infantile leukemia ; Leukemia ; Leukemic nodules ; Blastenkrise ; cerebrale Apoplexie ; Erstmanifestation ; Hyperleukocytose ; unreife Leukämie ; kindliche Leukämie ; Leukämie ; leukämische Knötchen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Unter 93 klinischen Fällen reifer und unreifer kindlicher Leukämien der letzten 10 Jahre zeigten nur 3 massive cerebrale Blutung als Erstmanifestation. Die Kinder −5 3/12 J. m., 2 1/12 J. w., und 10 3/12 J. m.—starben innerhalb 40, 48 bzw. 7 h. Charakteristischerweise fand sich eine extreme Hyperleukocytose mit 899000, 585000 und 360000 Zellen/mm3. Morphologisch ist das hämodynamisch bedingte quantitativ schwankende Blastenvorkommen in Venen und Arterien bemerkenswert, während lokale Unterschiede im Venenbefall offenbar stark von endovasalen Wachstumsschüben abhängen. Die Blasten breiten sich extravasal nicht nur passiv, sondern auch durch aktive Wanderung aus. Die hauptsächlich runde bis ovale Form der perivasculären Blasteninfiltrate wird hauptsächlich durch die. Virchow-Robinschen Räume bestimmt. Das Fehlen wachstumsstörender Hämodynamik und Gewebsstrukturen im cerebralen Ventrikelsystem und bei Netzhautabhebung begünstigt die Bildung leukämischer Knötchen. Neurologische Symptome bei hoher Blastenzahl weisen auf eine intracerebrale Blutung.
    Notes: Summary Among 93 clinical cases of mature and immature leukemia among children in the last 10 years only 3 showed massive cerebral hemorrhage as the lirst manifestation. The children-aged 5 3/12 yr., m., 2 1/12 yr., f., and 10 3/12 yr., m. died within 40, 48 and 7 h, respectively. Characteristically, an extreme hyperleukocytosis of immature cells with 89000, 585000, and 360000 cells/mm3, respectively was found. Morphologically the quantitatively varying occurrence of balsts in veins and arteries, basically of hemodynamic origin, is notable, while locally pronounced variations in the venous involvement apparently are strongly dependent upon endovasal growth periods of the blasts. The blasts penetrated extravasal areas not only via passive but also via active migration. The mainly round to oval shape of the perivascular infiltrates of blasts is determined especially by the Virchow-Robins' spaces. The abscence of growth disrupting hemodynamics and texture structures in the unhindered areas of the cerebral ventricle system and retinal detachement favors the formation of leukemic nodules. Neurological symptoms accompanying a high blast count point to a diagnosis of intracerebral hemorrhage.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00688071
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Untersuchungen Über die Abstammung und Klinische Bedeutung der Basophilen Erythrocytenpunktierung (1936)
    Springer
    Journal of molecular medicine 15 (1936), S. 1171-1171 
    Details
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01779486
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Horner's syndrome after treatment of tension pneumothorax with tube thoracostomy in a newborn infant (1980)
    Springer
    European journal of pediatrics 133 (1980), S. 67-68 
    Details
    ISSN: 1432-1076
    Keywords: Newborn infant ; Pneumothorax tube thoracostomy ; Horner's syndrome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A premature infant who developed respiratory distress syndrome required artifical ventilation. A right-sided tension pneumothorax at the age of 78 h was treated by insertion of a P.V.C. chest tube reaching deep into the right upper chest. At discharge on day 51 a Horner's syndrome of the right eye was noticed. Detailed examination at the age of one year revealed a typical peripheral preganglionar Horner's syndrome. Because other causes could be ruled out we assume that the lesion of the sympathetic nerve fibers was caused by the tip of the chest tube near the first thoracic intervertebral space.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00444758
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Reaction of term newborns with prolonged postnatal dyspnoea to early oxygen, mask continuous positive airway pressure, and volume expansion: A prospective, randomised, clinical trial (1996)
    Springer
    European journal of pediatrics 155 (1996), S. 805-810 
    Details
    ISSN: 1432-1076
    Keywords: Term newborns ; Dyspnoea ; Volume expansion ; Bicarbonate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Abstract In a prospective, randomised, open trial 103 term newborns with persisting dyspnoea, tachypnoea and/or cyanosis were treated with oxygen for 5–10 min and then with oxygen plus mask continuous positive airway pressure (CPAP) for another 5–15 min. Cases with overt prenatal or intrapartum obstetric pathology had been excluded from the study. Forty-one infants (40%) responded to this procedure within 10–25 min. The remaining 62 infants (60%) were randomly allocated to one of three forms of further treatment: continuation of mask CPAP for 20 min (group A,n=24), volume expansion with 9 ml of 3 ml albumin, 3 ml glucose, and 3 mEq of sodium bicarbonate (group B,n=24), or volume expansion with 4.5 ml albumin and 4.5 ml glucose (group C,n=14). There was no statistical difference in birth weight, gestational age or Apgar scores at 1 and 5 min between the infants of the groups. Time to normalisation of symptoms was significantly shorter in the volume expansion groups (B: 45±41 min, range 20–180, and C: 80±72 min, range 20–210) than in the mask CPAP group (A: 224±256 min, range 30–1200,P=0.02). There were statistical differences in umbilical cord and capillary pH values among the infants of the three groups, but the response to therapy was not related to the degree of acidaemia. Thirty-four infants (33%) who did not respond were admitted to a special care unit for further examination (group A: 21/24, group B: 7/24; group C: 6/14). Of these, 23 had no abnormal findings, 8 infants had radiological signs of transitory respiratory distress, and 1 had a nontension pneumothorax. Septicaemia was found in two infants. No infant was intubated. At discharge all 103 infants did well. Conclusion Incremental application of simple primary care procedures including volume expansion (with or without alkali) in term newborns with persisting postnatal tachypnoea and dyspnoea helps avoid overtreatment and unnecessary separation from the mothers in most cases and reliably selects infants who need close monitoring or special treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02002912
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Cerebral blood flow velocities in the first minutes of life (1993)
    Springer
    European journal of pediatrics 152 (1993), S. 269-270 
    Details
    ISSN: 1432-1076
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01956162
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Digoxin elimination by exchange transfusion (1977)
    Springer
    European journal of pediatrics 124 (1977), S. 217-222 
    Details
    ISSN: 1432-1076
    Keywords: Exchange transfusion ; Digoxin elimination
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es wird von vier Fällen berichtet, bei denen sich zugleich die Indikation zur Digitalisierung und zur Austauschtransfusion ergab. Nach vorhergehender, intravenöser Digoxingabe wurde einerseits das Verhalten der Digoxinkonzentration im Plasma gemessen, andererseits die gesamte durch den Blutaustausch eliminierte Glykosidmenge bestimmt. Besondere Beachtung galt einer Abhängigkeit des eliminierbaren Prozentsatzes von dem zeitlichen Abstand der Austauschtransfusion zur vorangehenden Injektion. In allen vier Fällen wurde ein mäßiges Absinken der Plasmakonzentration beobachtet. Die durch Austauschtransfusion eliminierte Digoxinmenge stand in einem verkehrt proportionalen Verhältnis zum Intervall zwischen Digoxingabe und Blutaustausch. In keinem Fall überstieg diese eliminierte Fraktion 5% der insgesamt im Körper enthaltenen Menge.
    Notes: Abstract The report covers four cases presenting simultaneous indications for digitalisation and exchange transfusions. Intravenous administration of digoxin was followed: 1. by monitoring of the behaviour of the plasma digoxin level; 2. by determination of the total amount of glycoside eliminated by the blood exchange. Particular attention was paid to the effect of the delay between injection and exchange transfusion on the amount of digoxin eliminated. All four cases showed moderate falls in plasma levels. The amounts of digoxin eliminated by exchange transfusion were in reverse relationship to the delay between administration of digoxin and the blood exchange. At no time did the eliminated fraction exceed 5% of the total amount present in the body.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00452113
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Reaction of term newborns with prolonged postnatal dyspnoea to early oxygen, mask continuous positive airway pressure, and volume expansion: a prospective, randomised, clinical trial (1996)
    Springer
    European journal of pediatrics 155 (1996), S. 805-810 
    Details
    ISSN: 1432-1076
    Keywords: Key words Term newborns ; Dyspnoea ; Volume expansion ; Bicarbonate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In a prospective, randomised, open trial 103 term newborns with persisting dyspnoea, tachypnoea and/or cyanosis were treated with oxygen for 5–10 min and then with oxygen plus mask continuous positive airway pressure (CPAP) for another 5–15 min. Cases with overt prenatal or intrapartum obstetric pathology had been excluded from the study. Forty-one infants (40%) responded to this procedure within 10–25 min. The remaining 62 infants (60%) were randomly allocated to one of three forms of further treatment: continuation of mask CPAP for 20 min (group A, n = 24), volume expansion with 9 ml of 3 ml albumin, 3 ml glucose, and 3 mEq of sodium bicarbonate (group B, n = 24), or volume expansion with 4.5 ml albumin and 4.5 ml glucose (group C, n = 14). There was no statistical difference in birth weight, gestational age or Apgar scores at 1 and 5 min between the infants of the groups. Time to normalisation of symptoms was significantly shorter in the volume expansion groups (B: 45 ± 41 min, range 20–180, and C: 80 ± 72 min, range 20–210) than in the mask CPAP group (A: 224 ± 256 min, range 30–1200, P = 0.02). There were statistical differences in umbilical cord and capillary pH values among the infants of the three groups, but the response to therapy was not related to the degree of acidaemia. Thirty-four infants (33%) who did not respond were admitted to a special care unit for further examination (group A: 21/24, group B: 7/24; group C: 6/14). Of these, 23 had no abnormal findings, 8 infants had radiological signs of transitory respiratory distress, and 1 had a non-tension pneumothorax. Septicaemia was found in two infants. No infant was intubated. At discharge all 103 infants did well. Conclusion Incremental application of simple primary care procedures including volume expansion (with or without alkali) in term newborns with persisting postnatal tachypnoea and dyspnoea helps avoid overtreatment and unnecessary separation from the mothers in most cases and reliably selects infants who need close monitoring or special treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02002912
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    Cytokine production by cord blood mononuclear cells stimulated with cows milk proteins in vitro: interleukin-4 and transforming growth factor β-secreting cells detected in the CD45RO T cell population in children of atopic mothers (2003)
    Oxford, UK : Blackwell Science Ltd
    Clinical & experimental allergy 33 (2003), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background Food antigens from the maternal circulation may sensitize fetal T cells in utero and be an important determinant in the development of food allergy.Methods Here we have examined the spontaneous and recall response to cow's milk proteins of cord blood mononuclear cells (CBMC) of newborn children, using single cell ELISPOT assays.Results In term newborns, confirming previous studies, the spontaneous cytokine response of CBMC is dominated by IL-4, IL-5, IL-10, and as shown here for the first time, TGF-β. For TGF-β only, the response of samples from infants of atopic mothers was significantly lower than samples from infants of non-atopic mothers. In vitro stimulation of CBMC with bovine serum albumin, casein and β-lactoglobulin resulted in a significant increase of all cytokine-secreting cells, again dominated by T helper type 2 (Th2) cytokines. There was a clear tendency for samples from infants of atopic mothers to have lower Th2 responses than samples from infants of non-atopic mothers, which was particularly significant for both IL-4 and TGF-β. Spontaneous cytokine secreting cells were virtually absent in cord blood from infants 〈 34 weeks gestation, as were cows milk protein-induced responses, although they were readily detectable in samples from infants aged 〉 34 weeks. To explore whether the cytokine secreting cells were in the naive CD4+ CD45RA population or memory CD4+ CD45RO T cells, these subsets were purified by positive and negative selection and tested for spontaneous and cows milk protein-induced cytokine responses. Strikingly, although the responses were small, the CD45RO+ cells from children of atopic mothers showed significant spontaneous and antigen-specific IL-4 and TGF-β responses, whereas the same population from infants of non-atopic mothers showed virtually no response. In addition CD45RA+ cells from infants of mothers with maternal atopy showed decreased IL-4 and TGF-β responses, especially the latter.Conclusions The cows milk antigen-specific IL-4 and TGF-β responses preferentially seen in the memory cell subset of infants with a maternal history of atopy strongly suggests Th2 skewing to dietary antigens in utero.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2222.2003.01646.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    Esophageal manometry (1986)
    Springer
    Pediatric surgery international 1 (1986), S. 177-183 
    Details
    ISSN: 1437-9813
    Keywords: Esophagus ; Manometry ; Infants ; Children ; Common cavity phenomenon
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Esophageal manometry offers estimations of actual pressure values of the esophagus and its sphincters provided that optimal equipment such as a low compliance pump is used. By means of these techniques, it has been shown that normal pressure values exist in the lower esophageal sphincter of newborns and infants. Peristalsis during deglutition in infants exhibits normal propulsive waves. A delay in peristaltic maturation may be observed in some newborns and infants with gastroesophageal reflux (GER). The upper esophageal sphincter has a slightly lower pressure in infants than in adults. A rarely reported but important manometric finding is the common cavity phenomenon (CCP): it is induced by relaxation of the lower esophageal sphincter, which allows reflux of gastric contents into the esophagus. Patients with pathological reflux exhibit the CCP more frequently and for longer periods of time than normal controls. Thus, this phenomenon offers an additional parameter in patients with GER. Together with simultaneous pH monitoring, esophageal manometry offers a comprehensive view of esophageal function under normal and disturbed conditions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00180920
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    Beitrag Zur Blutzuckerbestimmung Nach Crecelius Und Seifert (1935)
    Springer
    Journal of molecular medicine 14 (1935), S. 343-344 
    Details
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Apparatur und Angaben vonCrecelius undSeifert entsprechen, soweit dies auf Grund der mitgeteilten Untersuchungen gesagt werden darf, vollkommen den Anforderungen, welche aus theoretischen Erwägungen an sie gestellt werden müssen. Der Zusatz der Angabe in der Gebrauchsanweisung, daß auch nach Stunden noch colorimetriert werden darf, bzw. jener, daß sofortiges Abkühlen nicht unbedingt notwendig ist, erschiene zweckmäßig. Es erscheint angebracht, bei verschlossenen Röhrchen zu kochen. Die genaueste Einhaltung der vorgeschriebenen Menge NaOH sollte vielleicht noch stärker betont werden in Anbetracht der entscheidenden Beeinflussung der Braunfärbung durch den Gehalt an Lauge.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01779992
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...