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  • 1
    ISSN: 1432-0568
    Keywords: Key words Fish ; Pituitary gland ; Developmental biology ; Cell differentiation ; Immunohistochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  We previously reported the chronological appearance of adenohypophysial cells in freshwater teleosts using an immunocytochemical technique. The present study investigated the chronological appearance of adenohypophysial cells in the ayu, which is spawned and has its early development in brackish water, and the results were compared with those obtained in freshwater and seawater teleosts, as well as in other vertebrates. In the adult teleostean adenohypophysis, seven or eight types of secretory cells have been distinguished, each of which produce different hormones: prolactin (PRL), growth hormone (GH), thyroid stimulating hormone (TSH), gonadotropic hormones (GTH I and GTH II), adrenocorticotropic hormone (ACTH), melanophore stimulating hormone (MSH) and somatolactin (SL). In the pituitary of adult ayu, seven distinct types of glandular cells (PRL, GH, TSH, GTH, ACTH, MSH and SL cells) were identified. Chronologically, a few immunoreactive (ir)-PRL and ir-GH cells appeared in the ventral side of the pituitary one day before hatching. Then, just after hatching, ir-GTH cells were observed in the central to dorsal portion; ir-ACTH cells were found distributed in the anterior portion and some ir-MSH and a few ir-SL cells were seen in the posterior portion of the pituitary. Finally, a small number of ir-TSH cells were identified 50 days after hatching. These results differed from those obtained in other fishes previously reported with regard to the times of appearance of the PRL and GH cells. PRL cells appeared first, followed by GH cells in the freshwater teleosts, PRL and GH cells appeared at the same time in the brackishwater teleosts, while GH cells appeared first and PRL cells appeared last in the seawater teleosts. These results reflect the fact that PRL plays a major role in osmoregulation among freshwater teleosts, as compared with GH, which plays a similar role in seawater teleosts. It seems that both PRL and GH may play important roles in osmoregulation in brackishwater fish.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0509
    Keywords: Adrenal glands ; Adrenocortical adenoma ; Adipose tissue ; Computed tomography ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A case of adrenocortical adenoma containing small adipose foci is presented. A small amount of fat within the mass led to an erroneous preoperative diagnosis of myelolipoma. Adrenal adenoma should be included in the differential diagnosis of adrenal mass containing fat.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-0509
    Keywords: Liver, neoplasm ; Cavernous hemangioma ; Computed tomography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report a case of hepatic cavernous hemangioma with uncommon CT findings of multiple spotty calcifications arranged like a wreath in the marginal areas and no contrast enhancement.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0016-6480
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Slow reacting substance of anaphylaxis (SRS-A) is an important chemical mediator of bronchial asthma. Leukotriene C4 is a component of SRS-A and is synthesized from arachidonic acid. Its synthesizing and releasing processes are found to he Ca2+-dependent. We developed an in vivo inhalation asthma model, mainly mediated by SRS-A, and elucidated the relationship between a Ca2+-antagonist, nicardipine, and SRS-A. In the asthmatic model, mediated by endogenous SRS-A induced by antigen inhalation, continuous intravenous infusion of nicardipine 7 μg/kg/min depressed the open airway pressure by about 60% compared with the saline-treated group. Inhibition of mean pulmonary resistance (RL) was about 50% and that of the inverted value of dynamic compliance (1/Cdyn) about 36%. However, the same concentration of nicardipine did not significantly affect the airway response in the asthmatic model induced by the inhalation of leukotriene C4. These results suggest that nicardipine, at the concentration used in the present study, did not block the direct effect of SRS-A on the smooth muscle, but blocked the Ca2+ influx required for the synthesis of SRS-A and its release.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Slow-reacting substance of anaphylaxis (SRS-A) is an important factor mediating bronchoconstriction in asthma. We developed a guinea pig model for SRS-A-mediated bronchoconstriction induced by antigen inhalation. Using this model, we investigated the effect of N-(3′, 4′-dimethoxycinnamoyl) anthranilic acid (N-5′), a new anti-allergic drug, on the bronchoconstriction. FPL 55712 inhibited most of the bronchoconstriction induced by antigen inhalation. N-5′inhibited the antigen-induced bronchoconstriction in a dose-dependent fashion. Intraperitoneal administration of 200 mg/kg N-5′was effective for 40 min after antigen inhalation, while the effect of 60 mg/kg lasted only 7 min. On the other hand, 200 mg/kg N-5′showed no inhibitory effect on the bronchoconstriction caused by direct inhalation of leukotriene C4, a component of SRS-A. These findings indicate that one of the anti-allergic actions of N-5′is due to inhibition of synthesis and/or release of SRS-A.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-1114
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract  An experimental investigation of the vortical and turbulent structures in lobed jet mixing flows was conducted. The techniques of planar laser-induced fluorescence (PLIF) and particle image velocimetry (PIV) were used to accomplish flow visualisation and velocity filed measurements of the lobed jet mixing flows. Compared with a conventional circular jet flow, the lobed jet mixing flows were found to have a shorter laminar region, a smaller scale of spanwise Kelvin–Helmholtz vortices, quicker transition to turbulence and earlier appearance of small-scale vortical and turbulent structures. The intensive mixing of the core jet flow with ambient flow was found to concentrate within the first two nozzle diameters in the lobed jet mixing flow. More rapid growth of the shear layer at the near field and quicker decay of the central line velocity were also found in the lobed jet mixing flow. All these indicated a better mixing enhancement performance of the lobed nozzle compared with the conventional circular nozzle in the near-field region. Based on the PLIF and PIV results, two aspects of the mechanism of mixing enhancement in a lobed jet mixing flow were suggested. One is that a lobed nozzle can cause big azimuthal perturbations in the jet flow due to its special geometry, and the streamwise vortices produced by the lobed nozzle can enhanced the azimuthal perturbations. The “cut and connect” process of the large-scale spanwise Kelvin–Helmholtz vortex rings was accelerated. This is responsible for the avalanche of three-dimensional and smaller-scale motions and the generation of high turbulence. Another is that the “stretch effect” of streamwise vortices generated by the lobed nozzle on the spanwise Kelvin–Helmholtz vortical rings reduced the scale of the spanwise Kelvin–Helmholtz vortices, which also results in the creation of much small-scale intense turbulence and enhances the mixing of the core jet flow with the ambient flow.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Experiments in fluids 29 (2000), S. S085 
    ISSN: 1432-1114
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract A single-frame 3-D PTV algorithm was constructed to measure 3-D high-speed flows with NTSC cameras. The measurement system consists of three NTSC cameras, an optical instrument called AOM, a digital image grabber and a hosting computer. The tracking algorithm of particles' pair is based on a concept of a spatial match probability. The measurement system is used to probe the turbulent properties of the backward-facing step flow. A preliminary test of the measurement system is also made on the measurement of 3-D vectors of 36 targets on a rotating table to verify its validity. The measurement uncertainty of the system is systematically evaluated through the preliminary test. A set of virtual images is constructed by using the vectors selected randomly from the grid vectors that had been obtained by the experiment on the backward-facing step flow with the system. A performance test is made on the vector recovery using the virtual images and it is validated.
    Type of Medium: Electronic Resource
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