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  • 1
    Electronic Resource
    Electronic Resource
    Fine structure of fetal rat calvarium; provisional identification of preosteoclasts (1980)
    Springer
    Calcified tissue international 31 (1980), S. 21-28 
    Details
    ISSN: 1432-0827
    Keywords: Rat ; Calvarium ; Electron microscopy ; Preosteoclasts ; Osteoclasts
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary This is a study of the fine structure of cells of the 20-day fetal rat calvarium. Special attention is given to identifying and characterizing preosteoclasts. These cells are relatively common and located largely, but not exclusively, at the endocranial bone surface. The preosteoclasts are characterized by abundant mitochondria, an incomplete perinuclear Golgi apparatus, and variable-shaped dense granules. The dense granules are unique in appearance in that they contain an internal dense matrix surrounded by a clear halo. Most granules are circular in shape but some are elongate or tubular in form. Granules with identical appearance are observed in osteoclasts. The preosteoclasts are mononucleate, or occasionally binucleate. It is suggested that because preosteoclasts are morphologically distinctive and relatively abundant, it should be feasible to separate these cells from a heterogeneous cell isolate.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02407163
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Biologic Width and its Relation to Periodontal Biotypes (1998)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of esthetic and restorative dentistry 10 (1998), S. 0 
    Details
    ISSN: 1708-8240
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: Although average measurements of the biologic zone do not necessarily reflect any one clinical situation, they do establish a basis upon which clinical decisions can be made. Clinical impressions, human autopsy material, and animal studies support the concept of a biologic width. Impingement on the attachment in a susceptible host has shown adverse reactions, including gingival inflammation and alveolar bone loss. The concept is clinically important in determining the extent of osseous surgery necessary in the exposure of sound tooth structure. If the implant-abutment interface is considered to be similar to a subgingival crown margin, its importance in relation to peri-implant inflammatory disease is readily apparent. In the presence of inflammation, it is likely that epithelial migration would occur to a level apical to that source. Clinical observations indicate that, once the biologic attachment is invaded around the implant, the gingival reactions are similar to those found around natural teeth, whether the tissue is of the thick flat or thin scalloped type.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1708-8240.1998.tb00351.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    The effect of indomethacin on alveolar bone loss in experimental periodontitis (1982)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 17 (1982), S. 0 
    Details
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: This study was undertaken to determine if prostaglandins play a role in the events leading to loss of bone in the ligature model of periodontitis. Periodontitis was induced by placement of the ligatures around mandibular teeth on one side of the jaw of squirrel monkeys (Saimiri sciureus). From one day prior to ligature placement, half the animals were administered indomethacin (5 mg/kg/day), a potent inhibitor of prostaglandin synthesis. Animals were sacrificed after one and two weeks of experimental periodontitis. It was found that indomethacin treatment abolished the significant losses of alveolar bone height and bone mass seen in non-indomethacin-treated (NIT) animals following ligature placement. Indomethacin also depressed the large increase in osteoclast density measured at one week in the NIT animals. The results support the hypothesis that prostaglandins are an important mediator of bone loss in the ligature model of periodontitis. Evidence is also presented for the coupling of bone resorption with osteoblastic neo-osteogenesis on both periodontal ligament and endosteal bone surfaces.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0765.1982.tb01134.x
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    Paper (German National Licenses)
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