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  • 1
    ISSN: 0006-291X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0006-291X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Stem cell fate is influenced by specialized microenvironments that remain poorly defined in mammals. To explore the possibility that haematopoietic stem cells derive regulatory information from bone, accounting for the localization of haematopoiesis in bone marrow, we assessed mice that were ...
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0196-9781
    Keywords: D-Trp substitution ; PTH-related peptide (PTHrP) ; Parathyroid hormone (PTH) ; Partial agonist activity ; ROS 17/2.8 cells ; Receptor affinity ; Synthetic PTHrP analogues
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-5233
    Keywords: Diabetes education ; In-hospital care ; Nursing
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In order to test whether or not an in-service requalification course on diabetes care for health professionals (HP) of nondiabetological departments can enhance their level of knowledge about diabetes and the quality of care for diabetic inpatients admitted for reasons other than diabetes, we carried out a requalification course involving 171 HP (161 nurses and 10 midwives) from nondiabetological departments of our hospital. Areas of intervention were: general knowledge of diabetes (GKD), bedside monitoring of blood glucose (BMG), insulin preparation and administration (IPA), diagnosis and treatment of hypoglycemic crises (DTH), and hospitalization-related problems (HRP). HP, divided into groups of about 20 each, completed a basal evaluation by means of a 25-item multiplechoice questionnaire, and then attended six separate educative sessions, each focusing on one topic, consisting of a theory lesson and an interactive exercise of equivalent length. At the end of the course, HP were re-evaluated with the same questionnaire, and their skills in BMG, IPA and DTH were tested by means of specific operational checklists, which divided each complex operation into a sequence of single operations, and then compared them with those of a control group of untrained colleagues (CG). The global knowledge of diabetes after the course significantly improved, as gathered from the percentages of correct answers in each questionnaire (61.82%±23.64% vs 31.18%±20.00%;P〈0.001); separate analysis of different areas evidenced improvements in GKD (72.28%±12.47% vs 31.46%±20.56%;P〈0.01), BMG (68.77%±15.75% vs 37.50%±27.75%;P〈0.01), IPA (72.02%±11.72% vs 33.45%±21.22%;P〈0.05), and DTH (90.76%±6.86% vs 49.82%±26.68%;P〈0.05), but not in HRP. Professional skills profiles of HP, evaluated by measuring the number of errors done performing each task, were significantly (P〈0.001) better than those of CG, for BMG (1.09±0.73 vs 4.91±2.01), IPA (2.36±1.64 vs 5.64±2.25), and DHT (1.27±0.94 vs 3.82±1.12). Linear regression showed a significant (P〈0.001) correlation of skills and knowledge after the course for BMG (r2=.49), IPA (r2=.53), and DTH (r2=.61). Positive although nonspecific indicators of outcomes of the course were the increase (of about 100%) of requests to our metabolic unit for diabetologic consultations from other departments as well as the mentioning of diabetes in the diagnosis of discharge, and the 200% increase in the consumption of sticks for BMG. The course produced a significant improvement of knowledge and skills on specific diabetologic items among participants.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-5233
    Keywords: Key words Diabetes education ; In-hospital care ; Nursing
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In order to test whether or not an in-service requalification course on diabetes care for health professionals (HP) of nondiabetological departments can enhance their level of knowledge about diabetes and the quality of care for diabetic inpatients admitted for reasons other than diabetes, we carried out a requalification course involving 171 HP (161 nurses and 10 midwives) from nondiabetological departments of our hospital. Areas of intervention were: general knowledge of diabetes (GKD), bedside monitoring of blood glucose (BMG), insulin preparation and administration (IPA), diagnosis and treatment of hypoglycemic crises (DTH), and hospitalization-related problems (HRP). HP, divided into groups of about 20 each, completed a basal evaluation by means of a 25-item multiple-choice questionnaire, and then attended six separate educative sessions, each focusing on one topic, consisting of a theory lesson and an interactive exercise of equivalent length. At the end of the course, HP were re-evaluated with the same questionnaire, and their skills in BMG, IPA and DTH were tested by means of specific operational checklists, which divided each complex operation into a sequence of single operations, and then compared them with those of a control group of untrained colleagues (CG). The global knowledge of diabetes after the course significantly improved, as gathered from the percentages of correct answers in each questionnaire (61.82%±23.64% vs 31.18%±20.00%; P〈0.001); separate analysis of different areas evidenced improvements in GKD (72.28%±12.47% vs 31.46%±20.56%; P〈0.01), BMG (68.77%±15.75% vs 37.50%±27.75%; P〈0.01), IPA (72.02%±11.72% vs 33.45%±21.22%; P〈0.05), and DTH (90.76%±6.86% vs 49.82%±26.68%; P〈0.05), but not in HRP. Professional skills profiles of HP, evaluated by measuring the number of errors done performing each task, were significantly (P〈0.001) better than those of CG, for BMG (1.09±0.73 vs 4.91±2.01), IPA (2.36±1.64 vs 5.64±2.25), and DHT (1.27±0.94 vs 3.82±1.12). Linear regression showed a significant (P〈0.001) correlation of skills and knowledge after the course for BMG (r2=.49), IPA (r2=.53), and DTH (r2=.61). Positive although nonspecific indicators of outcomes of the course were the increase (of about 100%) of requests to our metabolic unit for diabetologic consultations from other departments as well as the mentioning of diabetes in the diagnosis of discharge, and the 200% increase in the consumption of sticks for BMG. The course produced a significant improvement of knowledge and skills on specific diabetologic items among participants.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-5233
    Keywords: Diabetes management ; Nursing ; Perioperative care ; Professional skills
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We tested the level of knowledge on diabetes and professional skills in a group of 60 non-diabetological health care professionals at the Policlinic of Pisa regarding the recognition and treatment of hypoglycaemia, the storage, mixing and administration of insulin, blood glucose stick monitoring, and the prevention and treatment of diabetic foot. The evaluation was carried out using a multiple-choice questionnaire and observation of the jubjects, performance by means of pre-defined observation of a blend of rapid-intermediate insulin, the use of blood glucose sticks and the management of a simulated hypoglycaemic crisis. As regards hypoglycaemia, 90% of subjects did not give a correct definition, 88.3% were unaware of the existence of asymptomatic hypoglycaemia, and 96.6% did not give a complete answer as to the treatment of hypoglycaemia. For insulin, 51.7% did not know the standards for correct storage of insulin, 88.3% did not know the difference between “clear” and “opaque” insulins, and 91.7% ignored the required interval between administration of regular insulin and meals. For foot care, 45% admitted that the problems with diabetics' feet were frequently not controlled, and between 21.7% and 63.3% did not known the hygiene rules for feet. Assessment of the performance of the subjects using schedules revealed incorrect use of sticks and administration of insulin (80.2% mixed and 92.4% injected the insulin incorrectly). There is clearly a need for education of non-diabetological health professionals regarding the disease. This is supported by the health professionals themselves, 94.5% of whom wished to participate in a course on diabetes.
    Type of Medium: Electronic Resource
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