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  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Cancer Genetics and Cytogenetics 28 (1987), S. 42 
    ISSN: 0165-4608
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
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    London, etc. : Periodicals Archive Online (PAO)
    British journal of psychology. 56 (1965) 461 
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 323 (1968), S. 56-65 
    ISSN: 1435-2451
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Nach einigen Vorbemerkungen zur Entwicklungsgeschichte und zur Nomenklatur der Nabelschnurbrüche werden die operativen und konservativen Behandlungsmethoden aus der Literatur zitiert und besprochen. Aus den Jahren 1949 bis 1965 werden 380 beschriebene, teils operativ, teils konservativ behandelte Fälle zusammengestellt. Beschreibung eines Falles mit Operationsverfahren unter Verwendung eines lyophilisierten Duratransplantates.
    Notes: Summary After some preliminary remarks about the embryology and nomenclature of omphalocele, the surgical and conservative methods of treatment are reviewed and discussed. 380 partly surgical and partly conservative treated cases, published between 1949 and 1965 are compiled. One case operated by using a duramater-homograft is described.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 259 (1976), S. 129-130 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Bone marrow cells in untreated acute myelogenous leukaemia (AML) show abnormal growth in vitro in the Robinson assay6. Characteristically, there is near total failure of colony formation; predominantly clusters are formed containing 20 cells or less7'8. Because such poor proliferation in vitro ...
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-1335
    Keywords: Drug sensitivity testing ; Bone marrow cells ; Human tumor colony-forming assay
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We investigated the responsiveness of human normal granulocyte-macrophage colony-forming units in culture (GM-CFUC) continuously exposed in vitro to 1 of 12 anticancer drugs. All drugs except bleomycin showed a simple negative exponential dosesurvival curve. The in vitro toxicity of drugs in GM-CFUC did not always correlate with the relative myelosuppressive potency observed in vivo. In addition, tumor specimens from 38 patients mainly with ovarian cancer were cultured in a human tumor colony-forming assay and continuously exposed to drugs at low, intermediate, and high concentrations capable of killing 40%, 78%, and 99% of GM-CFUC, respectively. The most active drugs were cis-platinum, velban, 5-fluorouracil, and 5-fluoro-ara-AMP. Dosesurvival curves of bone marrow progenitor cells may serve as an in vitro reference system for selecting appropriate drug concentrations of myelosuppressive drugs in drug-sensitivity assays of human tumors.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Archives of gynecology and obstetrics 238 (1985), S. 661-662 
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Die Zugabe von Medroxyprogesteron-Acetat (MPA) hatte keinen signifikanten Einfluß auf menschliche Knochenmarkszellen, die in vitro mit Adriamycin oder Cisplatin behandelt wurden. Dies deutet darauf hin, daß der klinisch beobachtete myeloprotektive Effekt von MPA bei Patienten, welche MPA plus Zytostatika erhielten, nicht durch einen direkten Wirkungsmechanismus auf Knochenmarkszellen erklärt werden kann.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Breast cancer research and treatment 26 (1993), S. S3 
    ISSN: 1573-7217
    Keywords: breast cancer ; cisplatin ; cyclophosphamide ; etoposide ; mitoxantrone ; stem cell transplantation ; thiotepa
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We have evaluated tandem cycles of a tri-drug combination, termed CVP (cyclophosphamide, etoposide [VP-16], and cisplatin [Platinol]), at four levels in more than 300 patients with various types of tumors. Tandem CVP appears to be at least therapeutically equivalent to alternatives. A second potentially noncross-resistant combination of mitoxantrone and thiotepa (MT), with or without etoposide, has been used in sequence following CVP to improve long-term, disease-free survival in patients who have multiple metastatic sites, who relapse shortly after adjuvant therapy, or who show other unfavorable clinical features. A combination of MT and etoposide (MVT) achieved an overall response rate of 61% in 32 patients with metastatic or refractory breast cancer. The etoposide was then eliminated to decrease the major toxicities of this regimen. MT was subsequently given to 37 evaluable patients prior to bone marrow infusion. The overall response rate was 48.5%. Thirty patients with metastatic breast cancer were then treated with induction therapy, a cycle of CVP, and then a cycle of MT. Given the low complete remission (CR) rate to induction therapy in these patients, the CR rate achieved with CVP-MT was encouraging. Further studies are ongoing.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1573-7217
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    European journal of wildlife research 26 (1980), S. 11-22 
    ISSN: 1439-0574
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Description / Table of Contents: Summary 1. Inquiries made in Lower Austria during two consecutive breeding periods and on two fixed days between (November, January) provided data about disperion pattern and breeding success of the Common Buzzard in different landscapes on a basis of average (1977) and high (1978) density of the Common Vole. 2. During all seasons the local population density is determined by the distribution of woods and open countryside and by the density of the Common Vole. In sparesly wooded areas woods can be densely populated by relatively many breeding-pairs, but their number is limited by the prevailing density of the Common Vole which has an influence on the extent of the Buzzard's individual cruising radius. In woodland habitats the presence of the Common Buzzard depends on the availability of suitably large open areas sufficiently rich in prey. During winter, the snow cover can cause the population to fluctuate, although the influence of the habitat on the local population density continues even during these periods. 3. The siting of eyries affects the difficulty of procuring prey. A poor supply of prey necessitates the eyrie being built near the edge of the woodland. 4. Eyries near the edge of the woodland and eyries in deciduous trees seem to be unfavourable for buzzards breeding early in the year. Microclimatic circumstances could play a role in this. 5. Breeding succes is determined by the efficiency of procuring food and the place of the eyrie with regard to the cruising radius. 6. The population of Common Buzzard which was studied is functioning successfully as regards self-regulation.
    Abstract: Resumé 1. Des enquêtes réalisées en Basse-Autriche au cours de deux périodes successives de couvaison et de deux journées intermédaires (novembre, janvier) ont permis de recueillir des données sur le mode de dispersion et sur les succès de l'élevage chez la Buse variable (Buteo buteo) dans différents sites et lors d'années avec densités moyennes de souris (1977) et fortes densités de souris (1978). 2. En toutes saisons les densités locales sont déterminées par la répartition „forêt-paysage ouvert“ et par l'abondance des souris. Dans des régions à faible taux de boisement la densité des couples nicheurs peut être relativement élevée, leur nombre étant cependant limité par le rayon d'action individuel, lequel est déterminé par l'abondance des souris. Dans les régions forestières, la densité de la Buse dépend de la présence de surfaces dégagées plus étendues et également plus riches en proies. Au cours de la mauvaise saison, l'enneigement peut déterminer des variations d'effectifs mais l'influence de la configuration du paysage sur les densités de population locales ne disparait pas pour autant. 3. La situation des aires de nidification est une question d'efficacité de la prédation. Une efficacité prédatrice moindre amène les oiseaux à installer leurs aires en bordure de la forêt. 4. Des aires installées en bordure de la forêt ou encore dans des feuillus constituent de toute évidence des situations défavorables pour la Buse, dont la période de nidification est précoce. A cet égard, des facteurs de micro-climat pouraient jouer un rôle. 5. Le succès de l'élevage des jeunes est déterminé par l'efficacité de l'approvisionnement alimentaire et par la situation de l'aire en relation avec le rayon d'action. 6. La population des buses étudiée ici se trouve dans une phase d'auto-régulation effective.
    Notes: Zusammenfassung 1. In Niederösterreich durchgeführte Erhebungen in zwei aufeinanderfolgenden Brutperioden und an zwei dazwischenliegenden Stichtagen (November, Januar) haben Unterlagen über Dispersionsmuster und Aufzuchterfolge beim Mäusebussard(Buteo buteo) in verschiedenen Landschaftssituationen bei durchschnittlichen (1977) und hohen (1978) Feldmausdichten erbracht. 2. Zu allen Jahreszeiten sind die lokalen Siedlungsdichten durch die Verteilung von Wald und offener Landschaft und durch das herrschende Feldmausangebot bestimmt. In waldarmen Gebieten können Waldflächen von relativ vielen Brutpaaren besiedelt werden, ihre Zahl ist aber durch die von der herrschenden Feldmausdichte beeinflußte Ausdehnung der individuellen Aktionsräume limitiert. In Waldlandschaften ist das Vorkommen von Mäusebussarden vom Vorhandensein entsprechend großer und ausreichend beutereicher offener Flächen abhängig. Im Winterhalbjahr kann Schneebedeckung Bestandsverschiebungen bedingen, der Einfluß der Landschaftssituation auf die lokalen Siedlungsdichten bleibt aber auch in diesen Perioden erhalten. 3. Die Lage der Horststandorte ist eine Frage der Effizienz der Beutebeschaffung. Geringe Fangeffizienzen erzwingen waldrandnahe Horststandorte. 4. Waldrandnahe Horststandorte und Horste in Laubbäumen sind für den jahreszeitlich früh brütenden Mäusebussard offensichtlich ungünstig. Mikroklimatische Faktoren können dabei eine Rolle spielen. 5. Der Aufzuchterfolg wird durch die Effizienz der Nahrungsbeschaffung und durch die Situation des Horststandortes in bezug zum Aktionsraum bestimmt. 6. Die untersuchte Population des Mäusebussards befindet sich im Stadium einer funktionierenden Selbstregulation.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1618-2650
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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