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Blood pressure and metabolic control as risk factors for nephropathy in Type 1 (insulin-dependent) diabetes (1985)

Hasslacher, Ch. ; Stech, W. ; Wahl, P. ; [et al.]

Springer

Diabetologia 28 (1985), S. 6-11

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ISSN: 1432-0428

Keywords: Type 1 diabetes ; diabetic nephropathy ; blood pressure ; metabolic control

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary The respective rôles of arterial blood pressure and metabolic control in different stages of diabetic nephropathy were analyzed retrospectively in 52 sequentially-followed Type 1 (insulin-dependent) diabetic patients. A negative correlation was found between median post-prandial blood glucose and median duration of diabetes until onset of persistent proteinuria (p〈0.01). Systolic blood pressure was higher in patients who subsequently developed persistent proteinuria than those who did not (140 versus 121 mmHg; p〈0.05), but duration of the interval until onset of persistent proteinuria was not related to blood pressure. After onset of persistent proteinuria, hypertensive diabetic patients developed elevated serum creatinine concentrations more frequently than normotensive diabetic patients (67% versus 14%, p〈0.05). In these patients, the delay until elevation of serum creatinine concentration was negatively correlated with blood glucose (p〈0.01). Once serum creatinine was raised, decay of renal function occurred faster in patients with persistent than intermittent hypertension (p〈0.05). No effect of metabolic control was demonstrable at this stage of nephropathy. It is concluded that metabolic control determines the early course of diabetic nephropathy, whereas blood pressure is more important in advanced stages of nephropathy.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00276992

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Einige Anwendungsfälle von Sonderschmierstoffen in der chemischen Industrie (1965)

Stech, W.

Weinheim : Wiley-Blackwell

Chemie Ingenieur Technik - CIT 37 (1965), S. 1248-1252

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ISSN: 0009-286X

Keywords: Chemistry ; Industrial Chemistry

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology

Notes: Einige Schmierprobleme aus der Betriebspraxis werden diskutiert. Es wird versucht, ihre Ursachen zu erkennen und Wege zur Lösung anzugeben. Neben den Möglichkeiten, synthetische Schmierstoffe, Festschmierstoffe und besondere Mineralöle zu verwenden, wird an Beispielen gezeigt, wie extreme Bedingungen durch konstruktive Maßnahmen und zweckmäßige Werkstoffauswahl - oft unter Ausnutzung des verarbeiteten Produkts als Schmierstoff - beherrscht werden können.

Additional Material: 3 Ill.