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  • 1
    Electronic Resource
    Electronic Resource
    Cardiac arrhythmias in subarachnoid haemorrhage (1988)
    Springer
    Acta neurochirurgica 93 (1988), S. 37-44 
    Details
    ISSN: 0942-0940
    Keywords: Subarachnoid haemorrhage ; cardiac arrhythmia ; autonomic nervous system
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In this prospective study 52 patients with spontaneous subarachnoid haemorrhage were examined with respect to cardiac arrhythmias and their relationship to cerebral lesions. A continuous ECG was registered over an average of five days. Sinus tachycardia was the most frequently recorded arrhythmia, followed by multifocal ventricular extrasystoles, couplets, frequent supraventricular extrasystoles, non-sustained ventricular tachycardia, asystolia and sinus arrhythmia. A significant correlation was found between the clinical manifestation of a midbrain syndrome and sinus arrhythmia, and multifocal ventricular extrasystoles. This correlation points to the autonomic cardiovascular centres as the structures involved.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01409900
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Has plasma renin activity a prognostic significance in subarachnoid haemorrhage? (1989)
    Springer
    Acta neurochirurgica 100 (1989), S. 25-30 
    Details
    ISSN: 0942-0940
    Keywords: Subarachnoid haemorrhage ; plasma renin activity ; sympathetic nervous system ; brainstem dysfunction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The possible relationship between plasma renin activity and neurological deficits was examined in ten patients with spontaneous subarachnoid haemorrhage in a prospective clinical study. The patients were examined daily, particular attention being given to signs of brain stem dysfunction. The degree of impaired consciousness was assessed using the Glasgow Coma Score. Plasma renin activity was determined on days 1–5, 7, 9, 11, 13, 15 and 21 after the initial bleeding episode using an Angiotensin-I-radioimmunoassay. Six of seven patients with signs of brain stem dysfunction displayed a marked increase in plasma renin activity. Thus a significant negative correlation between the degree of consciousness and the plasma renin activity resulted. An explanation for this correlation may be found in the localization of the autonomous centres and the high concentrations of renin in the hypothalamus and brain stem. The individual changes in plasma renin activity have prognostic significance, whereas single estimated plasma renin activities show great interindividual differences and have only limited prognostic value.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01405269
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Elevated serum CK-BB levels in patients with cerebral transtentorial herniation after ischemic stroke
    Amsterdam : Elsevier
    Clinical Biochemistry 22 (1989), S. 131-134 
    Details
    ISSN: 0009-9120
    Keywords: brain stem lesions ; ischemic stroke ; serum creatine kinase isoenzymes
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/S0009-9120(89)80011-6
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Elevated serum CK-BB levels in patients with cerebral transtentorial herniation after ischemic stroke
    Amsterdam : Elsevier
    Clinical Biochemistry 22 (1989), S. 131-134 
    Details
    ISSN: 0009-9120
    Keywords: brain stem lesions ; ischemic stroke ; serum creatine kinase isoenzymes
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/S0009-9120(89)80011-6
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Recurrent Torsade de Pointes type ventricular tachycardia in intracranial hemorrhage (1984)
    Springer
    Intensive care medicine 10 (1984), S. 263-264 
    Details
    ISSN: 1432-1238
    Keywords: Torsade de Pointes ; Ventricular tachycardia ; QT prolongation ; Intracranial hemorrhage
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Two out of 72 cases of intracranial hemorrhage-induced polymorphous ventricular tachycardia with typical Torsade de Pointes morphology are presented. Bot patients had marked QTc prolongation more than 550 ms. In one patient (QTc: 669 ms) Torsade de Pointes degenerated into fatal ventricular fibrillation. Even though polymorphous Torsade de Pointes type ventricular tachycardia is rare during the clinical course of intracranial hemorrhage, attention should be given to the QT interval. QTc prolongation more than 550 ms may carry a high risk of Torsade de Pointes type ventricular tachycardia and ventricular fibrillation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00256265
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Paraneoplastische Degeneration des unteren Motoneurons bei Bence-Jones-Plasmozytom (1999)
    Springer
    Der Onkologe 5 (1999), S. 734-737 
    Details
    ISSN: 1433-0415
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Neurologische Störungen können lange Zeit vor Entdeckung eines Tumorleidens auftreten. Auch Paraproteinämien und Lymphome treten gehäuft gleichzeitig mit der Degeneration unterer Neurone auf. Diese Kasuistik zeigt einen entsprechenden Verlauf.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007610050433
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Intrathecal thyrotropin-releasing hormone therapy of amyotrophic lateral sclerosis (1985)
    Springer
    Journal of neurology 232 (1985), S. 13-14 
    Details
    ISSN: 1432-1459
    Keywords: Amyotrophic lateral sclerosis ; Cerebrospinal fluid ; Thyrotropin-releasing hormone
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Six patients with amyotrophic lateral sclerosis were given from 800 to 4000 μg of thyrotropin-releasing hormone (TRH) intrathecally for a period of 2–6 months. The progressive course of this disease, manifested by increasing atrophy, paralysis and disability score, was not altered. This supports the hypothesis that the decrease in TRH content in the anterior horn region is secondary to the cellular destruction. TRH appears to play no significant role in the pathogenesis of amyotrophic lateral sclerosis
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00314033
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Direct evidence of hypertension and the possible role of post-menopause oestrogen deficiency in the pathogenesis of berry aneurysms (1985)
    Springer
    Journal of neurology 232 (1985), S. 67-72 
    Details
    ISSN: 1432-1459
    Keywords: Aneurysm ; ECG ; Hypertension ; Oestrogen ; Subarachnoid haemorrhage
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To determine the significance of hypertension in the pathogenesis of berry aneurysms, 113 patients with subarachnoid haemorrhage (SAH) and verified aneurysm and 63 patients with SAH without aneurysm were compared. Of those patients with angiographically verified aneurysms, 61.9% were found to have elevated blood pressure (〉160/95 mmHg) and 19.5% showed electrocardiographic signs of left ventricular hypertrophy (SV1+RV5 (6) 〉3.5 mV). The percentages for patients without aneurysm were 36.5% and 6.4% respectively. A significant correlation was found between anterior aneurysms and left ventricular hypertrophy (P〈0.01). The mean Sokolow index values were also significantly elevated in cases of aneurysm (P〈0.01). There was a complementary relationship between the extent of left ventricular hypertrophy and the percentage of females with regard to localization of an aneurysm and age group. The predominance of females in the total aneurysm population, in the 50- to 59-year-old age group, and among patients with internal carotid aneurysms indicates that a sex-specific hormonal factor may also play a role in the pathogenesis of aneurysms in addition to hypertension. The collagen wasting commonly observed in bone and skin in the post-menopausal period due to decreased oestrogen levels could possibly be responsible for the formation of aneurysms in the proximal segments of the cerebral arteries, as occurs in various connective tissue diseases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00313903
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  • 9
    Electronic Resource
    Electronic Resource
    Changes in nocturnal sleep in Huntington's and Parkinson's disease (1988)
    Springer
    Journal of neurology 235 (1988), S. 177-179 
    Details
    ISSN: 1432-1459
    Keywords: Sleep ; Spindle density ; Huntington's disease ; Parkinson's disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary There have been no reports of studies on nocturnal sleep or quantitative studies of sleep spindle density in Huntington's disease, whereas sleep in Parkinson's disease has been extensively reported. We therefore examined nocturnal sleep changes in patients with Parkinson's and Huntington's disease and compared them with a control group. The previously reported decrease in sleep spindle density was observed in patients with Parkinson's disease. The patients with Huntington's disease, however, had a significant increase in sleep spindle density, the nocturnal sleep pattern being normal in other respects when compared with the control group. This observation may provide a further diagnostic criterion in Huntington's disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00314313
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  • 10
    Electronic Resource
    Electronic Resource
    Bradycardia and second-degree AV block: an expression of the dominance of cholinergic activity in the rigid form of Huntington's disease (1983)
    Springer
    Journal of neurology 229 (1983), S. 129-132 
    Details
    ISSN: 1432-1459
    Keywords: Electrocardiography ; Heart block ; Parasympathetic nervous system ; Chorea, Huntington's
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es wird über einen 23jährigen Patienten mit der rigiden Form der Huntingtonschen Krankheit berichtet, bei welchem neben einem massiven Rigor und Tremor eine erhebliche Bradykardie und ein AV-Block II. Grades Typ I bestand. Unter der Gabe von Anticholinergika besserten sich die neurologischen Symptome und auch der AV-Block bildete sich vorübergehend zurück. Diese Störungen werden deshalb einem Überwiegen der cholinergen Aktivität zugeschrieben, im Gegensatz zu dem bekannten Defizit bei der hyperkinetischen Form.
    Notes: Summary A 23-year-old patient with the rigid form of Huntington's disease is reported who, in addition to severe rigidity and tremor, suffered from marked bradycardia and a type I second-degree AV block. With the administration of anticholinergics, the neurological symptoms improved and the AV block subsided temporarily. These disorders are therefore attributed to a dominance of cholinergic activity as opposed to the well-known deficit in the hyperkinetic form of Huntington's disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00313453
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