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  • 1
    Electronic Resource
    Electronic Resource
    Human stratum corneum polar lipids and desquamation (1985)
    Springer
    Archives of dermatological research 277 (1985), S. 284-287 
    Details
    ISSN: 1432-069X
    Keywords: Desquamation ; Epidermal lipids ; Ceramides ; Cholesteryl sulfate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The ceramides and steryl-sulfate components from desquamated and cohesive human stratum corneum were examined using a combination of chemical and chromatographic means. Six structurally distinct series of ceramides were identified, and the relative amounts of these species, as measured by quantitative thin-layer chromatography, did not differ in cohesive and desquamated stratum corneum. In contrast, the level of cholesteryl sulfate was significantly reduced in the desquamated material. The results are in accord with the hypothesis that cholesteryl sulfate serves in cell-to-cell cohesion within the stratum corneum, and its hydrolysis may be necessary to permit shedding of cells from the surface.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00509081
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Evaluation of a method for measuring the sustainable rate of sebaceous wax ester secretion (1987)
    Springer
    Archives of dermatological research 279 (1987), S. 266-269 
    Details
    ISSN: 1432-069X
    Keywords: Sebum secretion ; Bentonite method ; Thin-layer chromatography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Sebaceous was ester secretion rates were measured in six subjects on six occasions each, using absorption into bentonite clay and analysis of the collected lipid by quantitative thin-layer chromatography. On each occasion eight samples were collected, four from the left and four from the right side of the forehead in four successive intervals. The first two intervals, which totaled 14 h, were intended to deplete the follicular reservoir of sebum so that a constant rate of absorption could be obtained during the third and fourth intervals, which were 3 h each. Thin-layer analysis of each sample was done in triplicate. The data were examined using analysis of variance techniques to determine the reproducibility of the measurement method and to identify possible sources of variability. The intraclass correlation coefficient (r 1) for all 432 post-depletion determinations was 0.80. The reproducibility was considerably better for three of the subjects (r 1=0.93) than for the other three (r 1=0.75). Variability within the latter three subjects did not seem to be attributable to lack of reproducibility in the thinlayer analysis. Real biological variability also seems unlikely considering the holocrine mechanisms of sebum secretion. Therefore, the variability probably arises from non-representative collection of sebum into the bentonite absorbent.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00417326
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Effect of an orally administered arotinoid, Ro 15-0778, on sebum production in man (1988)
    Springer
    Archives of dermatological research 280 (1988), S. 152-154 
    Details
    ISSN: 1432-069X
    Keywords: Arotinoids ; Sebum production ; Acne
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 1,2,3,4-Tetrahydro-1,1,4,4-tetramethyl-y-[(E)-alpha-methylstyryl]-naphtalene (Ro 15-0778), a potent inhibitor of sebaceous gland activity in several animal models has been administered to male volunteers in dosages of 1, 2, 3, and 6 mg/kg/day and 2 g/day for 8 weeks. Sebum production was measured before treatment and after 4 and 8 weeks of therapy. At the dosage levels of 1,2,3, and 6 mg/kg/day there was no decrease in sebum secretion. With the dosage of 2 g/day, a significant decrease in sebum secretion was seen after 8 weeks of treatment with Ro 15-0778.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00456845
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Social and Cultural Influences on Psychopathology (1979)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Psychology 30 (1979), S. 397-415 
    Details
    ISSN: 0066-4308
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Psychology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.ps.30.020179.002145
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Sebaceous Gland Activity in Breast Cancer (1968)
    [s.l.] : Nature Publishing Group
    Nature 217 (1968), S. 463-465 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The physiological role of oestrogens in breast cancer has not been clearly elucidated, although this has been examined in some detail. Measurements of the urinary excretion of oestrogen metabolites in women with breast cancer as compared with age-matched control populations of healthy and ill ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/217463b0
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  • 6
    Electronic Resource
    Electronic Resource
    Skin Lipids and Acne (1975)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Medicine 26 (1975), S. 27-32 
    Details
    ISSN: 0066-4219
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.me.26.020175.000331
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    SEBACEOUS GLAND SECRETION IN CIRRHOSIS (1971)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 85 (1971), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: SUMMARY.— Sebum production tests were performed in 10 hospitalized male patients with cirrhosis of the liver. Sebum secretion in these patients did not differ significantly from that of normal subjects. No inverse correlation was evident between sebum levels and the presence or severity of oestrogenic physical signs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1971.tb07225.x
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Effect of cyproterone acetate-ethinyl estradiol treatment on the proportions of linoleic and sebaleic acids in various skin surface lipid classes (1986)
    Springer
    Archives of dermatological research 278 (1986), S. 481-485 
    Details
    ISSN: 1432-069X
    Keywords: Cyproterone acetate ; Ethinyl estradiol ; Sebum secretion ; Sebum composition ; Linoleic acid ; Acne
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of high-dose cyproterone acetateethinyl estradiol treatment on rates of sebum secretion and on the proportions of linoleic acid (18∶2Δ9,12) and sebaleic acid (18∶2Δ5,8) in the skin surface lipids of three female acne patients was examined. Changes in rates of sebum secretion were evaluated indirectly by measuring the ratio of wax esters/(cholesterol +cholesterol esters) in the subjects' skin surface lipid. In two of the subjects, this ratio indicated a reduction of sebum secretion rates to the childhood range. Concomitantly, there was an increase in linoleic acid and a decrease in sebaleic acid in all lipid classes. In the third subject, in whom there was only a small reduction in sebum secretion rate, the proportion of linoleic acid in the cholesterol esters more than doubled, but the changes in the other lipid classes were small or nonexistent. The results indicate that the proportions of linoleic acid and sebaleic acid in sebum are influenced by sebum secretion rates.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00455168
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