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  • 1
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Advanced materials research Vol. 33-37 (Mar. 2008), p. 133-138 
    ISSN: 1662-8985
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Fatigue crack growth under mixed mode loading conditions is simulated using S-FEM. Byusing S-FEM technique, only local mesh should be re-meshed and it becomes easy to simulate crackgrowth. By combining with auto-meshing technique, local mesh is re-meshed automatically, andcurved crack path is modeled easily. Plural fatigue crack problem is solved by this technique. Fortwo parallel crack problem, criteria of crack coalescence are proposed. By simulating this problem byS-FEM, it is verified these criteria are conservative ones
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1540-8159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: OHKI, R., et al.: Torsades de Pointes Ventricular Tachycardia Induced by Mosapride and Flecainide in the Presence of Hypokalemia. We report a 68-year-old man who developed torsades de pointes ventricular tachycardia induced by combined use of mosapride and flecainide. He had a permanent pacemaker (DDD mode) implanted because of sick sinus syndrome (bradytachy syndrome) 6 years earlier. The patient had started taking mosapride for upper abdominal discomfort 2 weeks earlier. On admission, ECG showed prolongation of the QTc interval from 0.48 to 0.56 seconds and self-terminating torsades de pointes occurred. We considered that this proarrhythmia was induced by mosapride in combination with antiarrhythmic agents.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Asia Pacific financial markets 2 (1995), S. 155-168 
    ISSN: 1573-6946
    Keywords: Samuelson's perpetual warrant model ; Barone-Adesi and Whaley's numerical method ; Margrave's exchange option ; optimal conversion price
    Source: Springer Online Journal Archives 1860-2000
    Topics: Economics
    Notes: Abstract It is well known among warrant traders that the Black & Scholes model cannot be directly used for warrant and convertible bond valuation. In this paper, a new warrant valuation model based on both the Samuelson and the Barone-Adesi & Whaley model is proposed, and the model is applied to convertible bond valuation. Our model is an extension of Samuelson's perpertual warrant model, whose parameters depend on stock price, volatility, term to maturity and interest rate.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Asia Pacific financial markets 3 (1996), S. 87-119 
    ISSN: 1573-6946
    Keywords: non-ideal Brownian motion ; generalized Langevin Equation ; memory ; time dependent nonlinear differential Equation ; Fourier-Laplace transform
    Source: Springer Online Journal Archives 1860-2000
    Topics: Economics
    Notes: Abstract Brownian motion has been extensively applied in the field of mathematical finance in modeling the stochastic processes of returns on securities. In this paper basic and generalized Langevin Equations with memory are used to augment Brownian motion to capture the well stylized facts of the financial market that frictions and imperfect information exist. The operator method of Fourier-Laplace transform with an appropriate kernel (influence function) is used to circumvent the difficulty associated with solving a time dependent nonlinear differential Equation, and a practical computational method is proposed. From the Langevin Equation, autocorrelation of the return process and the deviation of the return distribution from an ideal Brownian motion are extracted. It is also proven that the time-dependent differential Equation has a unique solution and that it is much more generalized than a martingale Brownian motion functional.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1573-2592
    Keywords: Endothelium ; macrophage ; inflammation ; chemokine ; adhesion molecule
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Interleukin-8 (IL-8) is a chemokine for polymorphonuclear leukocytes (PMNs) and lymphocytes, which promotes the extravasation of these inflammatory cells. In this study, we investigated IL-8 synthesis induced by the adhesive interaction between monocytes and endothelial cells during transmigration and the capacity of transmigrated monocytes to produce IL-8. Cocultured human monocytes and human umbilical vein endothelial cell (HUVEC) monolayers induced the synefgistic production of IL-8, compared with cultures of either monocytes or HUVEC monolayers alone. Coculture-induced IL-8 production almost doubled after HUVECs were stimulated with IL-1β. The induced IL-8 mRNA expression was consistent with the protein data, indicating the de novo synthesis of IL-8 by the coculture. Monoclonal antibodies (mAbs) against IL-8 inhibited the transendothelial chemotactic activity of the supernatants for PMNs by 55%. Immunohistochemistry revealed that both adherent and transmigrated monocytes and unstimulated HUVECs expressed IL-8 protein, whereas nonadherent monocytes did little. Transmigrated monocytes spontaneously secreted a 3.8-fold greater amount of IL-8 than the initial monocytes. Coculture-induced IL-8 production was inhibited about 30% by polyclonal Abs against IL-α, IL-1β, or tumor necrosis factor α, while it was not affected by mAbs against intercellular adhesion molecule 1 or vascular cell adhesion molecule 1. The results suggested that adhesive interaction during the transmigration of monocytes through HUVEC monolayers activates both cell types to produce IL-8 and that transmigrated monocytes are capable of producing ample IL-8.
    Type of Medium: Electronic Resource
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