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  • 1
    Electronic Resource
    Electronic Resource
    Improved method for routine determination of nicotine and its main metabolites in biological fluids
    Amsterdam : Elsevier
    Journal of Chromatography B: Biomedical Sciences and Applications 232 (1982), S. 295-303 
    Details
    ISSN: 0378-4347
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/S0378-4347(00)84169-9
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  • 2
    Electronic Resource
    Electronic Resource
    Glaskapillaren zur gaschromatographischen Analyse methylierter Purine und Pyrimidine
    Amsterdam : Elsevier
    Journal of Chromatography A 178 (1979), S. 330-336 
    Details
    ISSN: 0021-9673
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/S0021-9673(00)89726-5
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  • 3
    Electronic Resource
    Electronic Resource
    Die Induktion von Hirn- und Rückenmarktumoren bei Kaninchen mit N-Methyl-N-nitrosoharnstoff (1969)
    Springer
    Clinical and experimental medicine 150 (1969), S. 76-86 
    Details
    ISSN: 1591-9528
    Keywords: Brain neoplasms ; Neoplasms, experimental chemically induced ; Neoplasms, nervous tissue ; Nitroso compounds ; Rabbits ; Hirntumoren ; Chemisch induzierte experimentelle Tumoren ; Tumoren des Nervengewebes ; Nitrosoverbindungen ; Kaninchen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung In 48 auswertbaren Versuchen sind nach intravenöser Injektion von Methylnitrosoharnstoff bei 33 Kaninchen (68,8%) Hirntumoren und in 4 Fällen gleichzeitig Rückenmarktumoren entstanden. Histologisch handelt es sich vorwiegend um multiforme Glioblastome und um Sarkome. Geschwülste der Nervenwurzeln und peripheren Nerven wurden im Gegensatz zu Ratten nicht gefunden. Weitere Unterschiede in der Lokalisation der induzierten Tumoren nach Methylnitrosoharnstoff-Applikation gegenüber Ratten bestehen bei Kaninchen in dem häufigen Auftreten von Dünndarmcarcinomen und multiplen Gefäßwandsarkomen verschiedener Organe. Kaninchen sind bisher die größte Tierart, bei der mit Methylnitrosoharnstoff die Erzeugung von Hirntumoren gelungen ist. Die intravenöse Injektion von Methylnitrosoharnstoff erweist sich zur Zeit als die beste Methode zur Induktion von Geschwülsten des Zentralnervensystems bei ausgewachsenen Kaninchen.
    Notes: Summary After intravenous injection of methylnitrosourea among 48 rabbits in 33 (68.8%) brain tumors were found and in 4 of these cases spinal cord tumors simultaneously. Histologically these neoplasms were glioblastomas and sarcomas mainly. Contrary to rats tumors of nerve roots and of peripheral nerves were not observed. Unlike in rats the induced tumors frequently occured as small intestine carcinomas and as multiple vessel wall sarcomas of different organs. Rabbits are the largest animal species in which of brain tumors were successfully induced by methylnitrosourea. The intravenous injection of methylnitrosourea is the best method for induction of neoplasms of the central nervous system in adult rabbits at this time.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02045841
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  • 4
    Electronic Resource
    Electronic Resource
    Experimentelle Tumoren des Zentralnervensystems (1968)
    Springer
    Naturwissenschaften 55 (1968), S. 495-495 
    Details
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00599722
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  • 5
    Electronic Resource
    Electronic Resource
    Analyse von Organochlorpestizid-und PCB-Rückständen in Fischen mittels Kapillargaschromatographie/Massenspektrometrie (1981)
    Springer
    Chromatographia 14 (1981), S. 403-410 
    Details
    ISSN: 1612-1112
    Keywords: Capillary GC/MS ; Organochlorine residues ; PCB's ; Pesticides
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Summary The analysis of neutral organochlorine compounds in fish is described. The method includes extraction, selective clean-up and GC/MS determination using glass capillary columns. The results of a typical fish sample coming from Upper Austrian rivers are presented. In comparison with the detected concentration of 6.1 ppm PCB's relatively low amounts of pesticide residues were found. The degree of chlorination of these PCB's is similar to that of Aroclor 1254, but the isomeric distribution is quite different, indicating varying persistence of the distinct isomers.
    Notes: Zusammenfassung Es wird die Analyse neutraler organischer Chlorverbindungen in Fischen beschrieben. Die Methode umfaßt Extraktion, selektive Vortrennung und Bestimmung mittels GC/MS an Glastrennkapillaren. Weiter werden die Ergebnisse einer für oberösterreichische Flüsse typischen Fischprobe vorgestellt und diskutiert: Wie in den meisten Proben dieses Ursprungs findet man — im Vergleich zu einem Gehalt von 6.1 ppm PCB's — relativ wenig Pesticidrückstände. Der Chlorierungsgrad der gefundenen PCB's entspricht etwa dem von Aroclor 1254; die abweichende Isomerenverteilung deutet auf unterschiedliche Persistenz der einzelnen Isomere hin.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02262874
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  • 6
    Electronic Resource
    Electronic Resource
    Bestimmung polycyclischer Aromaten in Ruß mittels Gas-Chromatographie — Massenspektrometerie (1977)
    Springer
    Chromatographia 10 (1977), S. 350-357 
    Details
    ISSN: 1612-1112
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Mit Hilfe eines Gas-Chromatograph-Massenspektrometer-Computer-Systems wurden polycyclische Aromaten im Ofenruß eines Aluminiumelektrolyseofens analysiert. Die Extraktion des Rußes erfolgte mit Cyclohexan in einer Soxhletapparatur. Der Extrakt wurde ohne Vortrennung oder Anreicherung in den Gas-Chromatographen dosiert. Von jedem gas-chromatographischen Peak wurden mehrere Massenspektren erhalten, die mit Referenzspektren verglichen werden konnten. Von den rund 40 getrennten Komponenten wurden jene mit Konzentrationen von über 1 % bzw. erwiesener Carcinogenität auf Grund der Massenspektren und der relativen Retentionszeiten identifiziert. Als Hauptkomponenten wurden Fluoranthen, Pyren, Benz(a)anthracen und Phenanthren gefunden. Der Gehalt an Benz(a)pyren betrug 0,2 %.
    Notes: Summary The polynuclear aromatic hydrocarbons from the soot of an aluminium electrolysis furmace have been analysed by means of a gas chromatograph — mass spectrometer —computer system. After cyclohexane extraction (Soxhlet extractor) the liquid was directly injected into the chromatograph. Repeated scanning produced several spectra of each peak which could be compared with reference spectra. Out of about 40 separated compounds the carcinogens as well as the components with concentrations exceeding 1 % were identified by relative retention times and mass spectra. Fluoranthene, pyrene, benz(a)anthracene and phenan-threne were found to be the main components. The content of benzo(a)pyrene was 0.2 %.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02274483
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  • 7
    Electronic Resource
    Electronic Resource
    Prüfung des salzsauren Morphins (1880)
    Springer
    Fresenius' Zeitschrift für analytische Chemie 19 (1880), S. 505-505 
    Details
    ISSN: 1618-2650
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01341094
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  • 8
    Electronic Resource
    Electronic Resource
    Analysis of polycyclic aromatic compounds in the fly ash of an incineration plant for radioactive waste (1985)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 8 (1985), S. 524-527 
    Details
    ISSN: 0935-6304
    Keywords: Gas chromatography, GC ; Glass capillary columns ; Mass spectrometry ; Fly ash ; Polyaromatic hydrocarbons ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Organic compounds adsorbed on fly ash from an incinerator for radioactive waste were investigated. Following Soxhlet extraction and concentration, analysis was performed by GC and GC/MS using high temperature silylated glass capillary columns coated with OV-1 and SE-54. Compound identification was based on retention data, relative detector responses, and mass spectra. Among other polycyclic aromatic compounds, series of gradually chlorinated PAHs containing four to seven aromatic rings were detected. For unequivocal identification, appropriate reference compounds were synthesized by chlorination of the corresponding parent PAHs.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240080908
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