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  • 1
    Electronic Resource
    Electronic Resource
    Orbital pain and unruptured carotid-posterior communicating artery aneurysms: The role of sensory fibers of the third cranial nerve (1993)
    Springer
    Acta neurochirurgica 120 (1993), S. 7-11 
    Details
    ISSN: 0942-0940
    Keywords: Oculomotor nerve ; trigeminal nerve ; intracranial aneurysm ; orbital pain
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Intact aneurysms of the carotid siphon at the point of take-off of the posterior communicating artery may exhibit orbital pain, whether associated with oculomotor palsy or not as a warning symptom prior to rupture. In order to explain this symptom the hypothesis of a sensory pathway within the third cranial nerve, which is liable to compression by the enlarging aneurysm sac, has been investigated. Data from human autopsy material show evidence of sensory ganglion cells within the rootlets of the oculomotor nerve; furthermore, studies in animals prove that the third nerve contains sensory fibers which run proximally along the nerve bundles, enter the brainstem and reach the spinal trigeminal nucleus. These fibers come from the ophthalmic division of the fifth nerve and join the third nerve at the level of the lateral wall of the cavernous sinus. Although a number of questions remain to be solved, the presence of a sensory pattern within the third nerve could account for frontoorbital pain from enlarging aneurysms impinging on the third nerve itself.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02001462
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  • 2
    Electronic Resource
    Electronic Resource
    Vertebro-basilar aneurysms: Does delayed surgery represent the best surgical strategy? (1993)
    Springer
    Acta neurochirurgica 125 (1993), S. 5-8 
    Details
    ISSN: 0942-0940
    Keywords: Vertebrobasilar aneurysms ; timing of surgery ; subarachnoid haemorrhage ; early surgery ; delayed surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The appropriate time to perform surgery for posterior circulation aneurysms is debated. Controversy exists secondary to the lack of information regarding the overall management and outcome, as well as difficulties with their surgical treatment and infrequent occurrence. The present study examines the results of 46 patients with ruptured vertebro-basilar aneurysms treated with a delayed surgical protocol. Twenty-four were Hunt-Hess grade I/II on admission, 13 were grade III, and 9 grade IV/V. Nineteen patients (40%) (4 grade I/II, 6 grade III, and the 9 grade IV/V on admission) died before meeting the required conditions for surgery. Causes of death were vasospasm (8 cases), direct effect of the initial bleeding (7 cases), and rebleeding (4 cases). Surgical results were excellent/good in 87% of the patients. Surgical mortality was 8% (2 out of 24). In this study, despite encouraging surgical results, overall mortality was disappointingly high. We suggest that as more experience is gained in treating vertebrobasilar aneurysms, early surgery should be performed in selected cases. Early surgery is prophylactic for rebleeding and allows for more aggressive treatment of cerebral vasospasm.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01401820
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  • 3
    Electronic Resource
    Electronic Resource
    Posterior fossa haemangioblastomas: Angiography versus computed tomography (1985)
    Springer
    Acta neurochirurgica 76 (1985), S. 23-27 
    Details
    ISSN: 0942-0940
    Keywords: Haemangioblastoma ; posterior fossa ; vertebral angiography ; CT scanning
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A series of 57 patients harbouring a total of 63 haemangioblastomas of the posterior fossa is reviewed. Some clinical data are pointed out and the findings of vertebral angiography and computed tomography scanning performed in 61 and 38 lesions, respectively, are examined. The results obtained in the last 38 cases, undergoing both examinations, are compared, and some notes on differential diagnosis with other expansive lesions of the posterior fossa are given.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01403825
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  • 4
    Electronic Resource
    Electronic Resource
    Intramedullary cystic teratoma (1982)
    Springer
    Acta neurochirurgica 62 (1982), S. 101-108 
    Details
    ISSN: 0942-0940
    Keywords: Congenital tumour ; spinal cord compression ; teratoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An uncommon case of intramedullary cystic teratoma with a history of intermittent symptoms is reported. Subtotal removal was performed with relief of symptoms for four years since operation. The histogenetic hypotheses of spinal cord teratomas are briefly reviewed, and the trigerminal origin of these tumours is stressed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01402216
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  • 5
    Electronic Resource
    Electronic Resource
    Percutaneous trigeminal thermorhizotomy in treatment of malignant facial pain (1983)
    Springer
    Acta neurochirurgica 69 (1983), S. 283-289 
    Details
    ISSN: 0942-0940
    Keywords: Percutaneous trigeminal thermorhizotomy ; malignant facial pain ; painful anaesthesia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Fifty-eight patients suffering from intractable pain in the trigeminal distribution due to neoplasms of the intracranial or facial regions underwent controlled percutaneous coagulation of the Gasserian ganglion (trigeminal thermorhizotomy). Of them, 35 were evaluated at varying time intervals from the intervention (mean: 7 months). While pain was completely relieved in 71 per cent of cases at discharge, the follow-up examination was consistent with 49 per cent of analgesias. The rationale of percutaneous thermocoagulation in malignant facial pain is given and the pertinent literature summarized.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01401815
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  • 6
    Electronic Resource
    Electronic Resource
    Spontaneous resolution of acute extradural hematomas - study of twenty-five selected cases (1989)
    Springer
    Neurosurgical review 12 (1989), S. 188-189 
    Details
    ISSN: 1437-2320
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01790645
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  • 7
    Electronic Resource
    Electronic Resource
    Particular features of cell-mediated immunity in patients with anaplastic gliomas (1983)
    Springer
    Journal of neuro-oncology 1 (1983), S. 327-332 
    Details
    ISSN: 1573-7373
    Keywords: tumor immunobiology ; gliomas ; ADCC ; SLMC
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The authors studied 24 patients affected by anaplastic gliomas in regard to the killer (Antibody-Dependent Cellular Cytotoxicity) and natural killer (Spontaneous Lymphocyte-Mediated Cytotoxicity)immunological functions, by counting the Cr51 release in Chang liver and K 562 cell cultures, respectively. These parameters were also evaluated in 24 healthy donors as control, in 24 patients affected by bladder cancer and in nine cases of kidney cancer. Our data show, pre-operatively, a statistically significant impairment of ADCC and SLMC activity in glioma patients as compared both with controls, bladder and kidney cancer patients. The particular impairment of K and NK functions in gliomas is discussed with regard to the specific features of Central Nervous System malignancies. An improvement of ADCC activity was also found in the post-operative samples. This finding confirms other reports about partial restoring of altered immunocompetence after surgery, suggesting a link between extention of tumor mass and impaired immunological reactions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00165716
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  • 8
    Electronic Resource
    Electronic Resource
    Intracranial microvascular decompression for “cryptogenic” hemifacial spasm, trigeminal and glossopharyngeal neuralgia, paroxysmal vertigo and tinnitus: I. Surgical technique and results (1986)
    Springer
    Neurological sciences 7 (1986), S. 359-366 
    Details
    ISSN: 1590-3478
    Keywords: Intracranial microvascular decompression ; “idiopathic” cranial nerve dysfunctions ; trigeminal neuralgia ; hemifacial spasm ; glossopharyngeal neuralgia ; paroxysmal vertigo
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Sommario Sono stati operati con intervento di decompressione microvascolare dei nervi cranici 21 pazienti su 24 affetti da emispasmo del facciale (8 casi), nevralgia del trigemino (12 casi), nevralgia del glossofaringeo (3 casi), vertigini parossistiche (1 caso). In 21 casi fu riscontrata all'intervento un'ansa vascolare anomala comprimente il nervo all'emergenza dal tronco. La separazione dell'arteria dal nervo con tecnica microchirurgica ha consentito di risolvere i disturbi in tutti i casi eccetto due che presentarono una recidiva precoce: in uno di questi il reintervento fu risolutivo. In due pazienti con nevralgia del trigemino furono riscontrati due piccoli tumori benigni dell'angolo ponto-cerebellare non evidenziati dagli accertamenti neuroradiologici pre-operatori. In un caso non è stata riscontrata alcuna lesione compressiva. I risultati ottenuti confermano l'efficacia dell'intervento, e indicano come queste patologie siano erroneamente ritenute essenziali.
    Notes: Abstract Intracranial microvascular decompression was performed in 21 out of 24 patients with hyperactive dysfunction of cranial nerves: 8 cases of hemifacial spasm, 12 of trigeminal neuralgia, 3 of glossopharyngeal neuralgia and 1 case of paroxysmal vertigo and tinnitus. In 21 cases an abnormal vascular loop was found to impinge on the root entry zone of the nerve in the brainstem. Dissection of this loop with decompression of the nerve resulted in long-lasting relief of symptoms in all but two patients who presented early recurrence; in one of these a second procedure was eventually successful. In two patients with trigeminal neuralgia a benign tumor of the cerebellopontine angle that had escaped preoperative diagnosis was present. Finally, in one case no compressive lesions were found. From the data of the literature and from our present experience microvascular decompression can be considered a safe as well as an effective procedure, affording a high success rate in conditions often or usually resistant to medical treatment and erroneously considered “idiopathic”.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02340876
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  • 9
    Electronic Resource
    Electronic Resource
    Intracranial microvascular decompression for “cryptogenic” hemifacial spasm, tirgeminal and glossopharyngeal neuralgia, paroxysmal vertigo and tinnitus: II. Clinical study and long-term follow up (1986)
    Springer
    Neurological sciences 7 (1986), S. 367-374 
    Details
    ISSN: 1590-3478
    Keywords: “Cryptogenic” cranial nerve dysfunction syndromes ; trigeminal neuralgia ; hemifacial spasm ; glossopharyngeal neuralgia ; paroxysmal vertigo and tinnitus ; intracranial microvascular decompression ; long-term results
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Sommario Venti pazienti affetti da forme “essenziali” di nervralgia trigeminale (9 casi), emispasmo facciale (7 casi), nevralgia glosso-faringea (3 casi) e vertigine e tinnito parossistici (1 caso), operati di decompressione microvascolare, sono stati riesaminati ad una distanza media dall'intervento di 25 mesi. In 19 pazienti (95%) si è osservata la completa guarigione, in assenza di deficit funzionali a carico dei nervi cranici interessati. In base ai dati clinici e neuroradiologici, i pazienti qui descritti non sono differenziabili dal gruppo generale di malati con forme “idiopatiche” di nevralgia od emispasmo. Viene sottolineata l'importanza del fattore compressivo vascolare nel determinismo delle disfunzioni “essenziali” dei nervi cranici, e se ne discutono le interpretazioni fisiopatologiche. Si suggerisce quindi la necessità di rivedere il concetto di “idiopatico” applicato a tali condizioni morbose. Infine vengono definite le precise indicazioni ed il ruolo della decompressione microvascolare nella terapia della patologia “essenziale” dei nervi cranici.
    Notes: Abstract 20 patients who had undergone microvascular decompression for the treatment of “idiopathic” trigeminal neuralgia (9 cases), hemifacial spasm, (7 cases), glossopharyngeal neuralgia (3 cases) and paroxysmal vertigo and tinnitus (1 case) were followed up for 25 months on average. Permanent relief of symptoms was observed in 19 (95%), with sparing of cranial nerve function. Analysis of the clinical data shows that the patients described in the present series did not differ from those considered to suffer from “idiopathic” cranial nerve dysfunction syndromes. The importance of vascular cross compression as etiological factor in such conditions is stressed and the pathophysiology discussed. The term “cryptogenic” applied to trigeminal neuralgia or hemifacial spasm thus needs revising. Lastly, the indications of microvascular decompression in the treatment of “cryptogenic” cranial nerve dysfunction syndromes are defined.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02340877
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