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  • 1
    Electronic Resource
    Electronic Resource
    Effects of 2,3-Butanedione 2-Monoxime on Ca2+ Release Channels (Ryanodine Receptors) of Cardiac and Skeletal Muscle (1999)
    Springer
    The journal of membrane biology 169 (1999), S. 189-198 
    Details
    ISSN: 1432-1424
    Keywords: Key words: Ca2+ release channel — Ryanodine receptor — Sarcoplasmic reticulum — 2,3-butanedione 2-monoxime — Skeletal muscle — Cardiac muscle
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract. Single channel and [3H]ryanodine binding measurements were performed to test for a direct functional interaction between 2,3-butanedione 2-monoxime (BDM) and the skeletal and cardiac muscle sarcoplasmic reticulum Ca2+ release channels (ryanodine receptors). Single channel measurements were carried out in symmetric 0.25 m KCl media using the planar lipid bilayer method. BDM (1–10 mm) activated suboptimally Ca2+-activated (0.5–1 μm free Ca2+) single, purified and native cardiac and skeletal release channels in a concentration-dependent manner by increasing the number of channel events without a change of single channel conductances. BDM activated the two channel isoforms when added to either side of the bilayer. At a maximally activating cytosolic Ca2+ concentration of 20 μm, BDM was without effect on the cardiac channel, whereas it inhibited skeletal channel activities with IC50≈ 2.5 mm. In agreement with single channel measurements, high-affinity [3H]ryanodine binding to the two channel isoforms was increased in a concentration-dependent manner at ≤1 μm Ca2+. BDM was without a noticeable effect at low (≤0.01 μm) Ca2+ concentrations. At 20 μm Ca2+, BDM inhibited the skeletal but not cardiac channel. These results suggest that BDM regulates the Ca2+ release channels from the sarcoplasmic reticulum of skeletal and cardiac muscle in a concentration, Ca2+ and tissue-dependent manner.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002329900530
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  • 2
    Electronic Resource
    Electronic Resource
    Molecular beam study of photoionization of uranium and uranium oxide
    Amsterdam : Elsevier
    Optics Communications 45 (1983), S. 179-182 
    Details
    ISSN: 0030-4018
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0030-4018(83)90350-4
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Dual electrolyte-semiconductor contact CdSe electrochemical photocell (1987)
    Springer
    Journal of applied electrochemistry 17 (1987), S. 1100-1103 
    Details
    ISSN: 1572-8838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Electrical Engineering, Measurement and Control Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01024376
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Interchain crosslinking between NBR and polyacrylic rubber and effect on (i) processibility and blend-morphology (1994)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 51 (1994), S. 245-251 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Flow behaviour of NBR and polyacrylic rubber blends have been studied throughout the entire composition ranges. The effect of preheating of the blends is also studied in order to understand the interchain crosslinking. Viscosity, extrudate swell, power law indices, have been studied as a function of shear rate and blend ratio. The shearing accompanied by blend ratio has a predominent effect on the rheological behaviour of the preheated blends due to microgel formation. From the rheological behaviour it appears that there is a phase inversion at around 50% of NBR, however, preheating does not change this trend. © 1994 John Wiley & Sons, Inc.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1994.070510206
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