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  • 1
    ISSN: 1432-1076
    Keywords: Chronic granulomatous disease ; Sulfamethoxazole-trimethoprim
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Seven male Japanese children with chronic granulomatous disease were given sulfamethoxazole-trimethoprim (SMX-TMP) for recurrent pyogenic infections, most of which had proved difficult to control with other antibiotics. With continuous treatment the children remained free of infections severe enough to necessitate hospitalization, except on one occasion. Serious complications, including hematological disorders, never occurred during therapy and there were no changes in leukocyte function during therapy. These results indicate that SMX-TMP should be considered in the treatment of bacterial infections associated with chronic granulomatous disease.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 68 (1990), S. 3212-3220 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We have investigated p-type doping of Li and Na impurities by ion implantation into ZnSe heteroepitaxial layers grown at very low temperatures (250 °C) by atmospheric pressure metalorganic vapor-phase epitaxy. The activation rates of shallow acceptor levels, the density of self-activated centers in the implanted-ZnSe epitaxial layers (epilayers), and the degradation of crystalline quality due to radiation damage are dependent on the ion implantation and annealing conditions. As the dose density changes, so do the optimum annealing conditions for the degrees of activation and the recovery of radiation damage. Also the depth profile of the implanted ions and damage is greatly influenced by the acceleration energy. It is difficult to decide on the optimum annealing conditions at the different acceleration energies and to assess the crystalline quality of the implanted epilayers with a nonuniform depth profile of the implanted ions, because the region analyzed is restricted near to the surface and does not always coincide with the implanted region in the epilayer. We have confirmed that the high-temperature annealing does not cause the damage to propagate deeply into the implanted epilayers, although it has been a cause of much concern in II-VI compounds.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 68 (1990), S. 5674-5681 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Single crystalline epitaxial layers of undoped ZnS have been grown at 250–300 °C on (100)-oriented GaAs substrates by atmospheric pressure metalorganic vapor phase epitaxy using dimethylzinc (DMZ) and hydrogen sulfide as source materials. The premature reaction typically encountered with this source combination can be eliminated completely as well as in the case of ZnSe epitaxial growth using DMZ and hydrogen selenide, even at atmospheric pressure, by controlling the source gas velocity and the mole ratio. ZnS heteroepitaxial layers (heteroepilayers) with excellent mirrorlike surface morphologies, which were grown at 250 °C for the source gas mole (VI/II) ratio below 10, were obtained. The VI/II ratio dependence of the ZnS heteroepilayers is very different from that of ZnSe heteroepilayers, whose surface morphologies are mirrorlike at a VI/II ratio above 10. Also the surface morphologies of the ZnS heteroepilayers gradually begin to degrade as the growth temperature increases above 250 °C. Moreover, below 220 °C, the crystalline quality abruptly changes to polycrystal, as with bad hazy morphology, which is similar to that seen in ZnSe heteroepilayers grown below 210 °C. It is shown that it is necessary to grow ZnS layers epitaxially at least higher than 220 °C.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 66 (1995), S. 2867-2869 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A correlation between the partial pressure of dichlorosilane gas (SiH2Cl2) and the incorporation of oxygen (O) and chlorine (Cl) atoms into the low-temperature (850 °C) epitaxial films was found. The profiles of O and Cl concentrations in the epitaxial films were measured by secondary ion mass spectroscopy. Incorporation of O and Cl atoms into the growth films during the epitaxial growth was suppressed by increasing the partial pressure of SiH2Cl2. The growth rate linearly increased with the partial pressure of SiH2Cl2 and eventually saturated. Incorporation of O atoms was inhibited and fine removal of Cl atoms was achieved when the growth rates saturated. The epitaxial films with high O and Cl concentrations had a microroughened surface (root mean square of microroughness (approximately-greater-than)0.4 nm). The microroughness was also improved by increasing the partial pressure of SiH2Cl2. The coverage of kinks and/or hollow bridge sites by hydrogen (H) and Cl atoms seems to restrict the reaction of O and water (H2O) with the growth front surface. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Chester : International Union of Crystallography (IUCr)
    Journal of synchrotron radiation 5 (1998), S. 969-971 
    ISSN: 1600-5775
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Geosciences , Physics
    Notes: As a basic layered structure for giant magnetoresistive (GMR) heads, NiFe/Cu/NiFe/Ta/Si substrate was measured by X-ray reflectometry at Cu Kα, Cu Kβ and Cu K-absorption-edge energies. The accuracy of both the Cu thickness and the interface width between the upper NiFe and the Cu layers was found to improve in the order Cu Kα 〈 Cu Kβ 〈 Cu K-edge. The final thickness and interface width values obtained from Cu Kβ reflectivity are in good agreement with those from the Cu K-edge. The anomalous-dispersion effect is useful in the more accurate analysis of the layered structure of transition metal multilayers because it causes a large difference in the refractive indices of specific elements near the absorption edge. The Kβ X-rays, which can be produced from conventional X-ray sources, are also available for the accurate analysis of reflectivity measurements.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The value of radical systematic lymphadenectomy for treatment of early-stage bronchial carcinoma is controversial. We performed a prospective randomized study to address this question. Altogether 115 patients with peripheral non-small-cell lung cancers smaller than 2 cm in diameter were enrolled in this study. They were randomly assigned into a lobectomy with lymph node sampling group (sampling group, n = 56) or a lobectomy with radical systematic lymph node dissection group (dissection group, n = 59). Inclusion criteria were based only on preoperative clinical studies. Four tumors were larger than 2 cm postoperatively. One patient had disseminated disease, and two had intrapulmonary metastases discovered at surgery. Two patients had small-cell carcinoma. There were four with pathologic N1 disease and seven with N2 disease in the dissection group and three with N1 and eight with N2 disease in the sampling group. The numbers of local and distant recurrences were two and six, respectively, in the dissection group and two and five in the sampling group. The overall 5-year survival was 81% in the dissection group and 84% in the sampling group. No significant differences in the recurrence rate or survival was seen between the groups. Our results demonstrate that clinically evaluated peripheral non-small-cell carcinomas smaller than 2 cm in diameter do not require radical systematic mediastinal and hilar lymph node dissection.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1436-2813
    Keywords: Key Words: thoracoscopy ; cost ; wedge resection ; lobectomy ; video-assisted thoracic surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: n = 30) and a VATS lobectomy for lung cancer (n = 10) were compared with the costs in similar patients undergoing a wedge resection (n = 20) and lobectomy (n = 20) using open techniques. The disposable instrument costs were US $1 071 higher for a VATS wedge resection; however, the operative time was shorter (0.99 h for VATS versus 1.75 h for the open procedure). The length of hospital stay was also shorter after a VATS wedge resection (10.4 days for VATS versus 16.8 days for the open procedure), thus resulting in lower total hospital charge in the VATS group. The disposable instrument costs were $3 190 higher for a VATS lobectomy, and the operative time was longer (5.56 h for VATS versus 4.25 h for the open procedure). The length of hospital stay was similar in both groups (25.2 days for VATS versus 27.7 days for the open procedure), thus resulting in a higher total hospital charge in the VATS lobectomy group. The cost of a VATS wedge resection for removing peripheral nodules is competitive with that of open techniques, but the cost of a VATS lobectomy is higher than that for an open lobectomy.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1436-2813
    Keywords: thoracoscopy ; cost ; wedge resection ; lobectomy ; video-assisted thoracic surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We reviewed our experience with video-assisted thoracic surgeyr (VATS) in our most recent 80 patients for the purpose of cost analysis. The costs incurred in the patients undergoing a VATS wedge resection for nodules (n=30) and a VATS lobectomy for lung cancer (n=10) were compared with the costs in similar patients undergoing a wedge resection (n=20) and lobectomy (n=20) using open techniques. The disposable instrument costs were US $1071 higher for a VATS wedge resection; however, the operative time was shorter (0.99h for VATS versus 1.75h for the open procedure). The length of hospital stay was also shorter after a VATS wedge resection (10.4 days for VATS versus 16.8 days for the open procedure), thus resulting in lower total hospital charge in the VATS group. The disposable instrument costs were $3190 higher for a VATS lobectomy, and the operative time was longer (5.56 h for VATS versus 4.25 h for the open procedure). The length of hospital stay was similar in both groups (25.2 days for VATS versus 27.7 days for the open procedure), thus resulting in a higher total hospital charge in the VATS lobectomy group. The cost of a VATS wedge resection for removing peripheral nodules is competitive with that of open techniques, but the cost of a VATS lobectomy is higher than that for an open lobectomy.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. At our institute patients with lung cancer had traditionally undergone lobectomy with mediastinal lymph node dissection using a standard posterolateral approach. The considerable morbidity associated with the standard posterolateral thoracotomy led us to investigate an alternative muscle-sparing approach. A prospective, randomized study of 30 patients with primary lung cancer (stage I or II) was performed to compare the following: operative field size, number of dissected lymph nodes, surgery time, postoperative pain, shoulder range of motion, and pulmonary function test results between patients who underwent either standard thoracotomy (SP group, n = 15) or the muscle-sparing thoracotomy (MS group, n = 15). The procedure should provide enough operative field size to access the mediastinum. Compared with the standard posterior thoracotomy, the muscle-sparing thoracotomy supplied a smaller operative field (218 ± 31 versus 165 ± 41 cm 2 ) and required more surgery time (87 ± 13 minutes) than the standard posterior thoracotomy (66 ± 12 minutes). There were no significant differences in the number of dissected mediastinal lymph nodes. During the early postoperative days, pain and restriction of shoulder flexion were significantly less in the MS group than in the SP group. There were no significant differences in pulmonary function between the two groups. In terms of the operative field there is a marked disadvantage with the muscle-sparing incision compared with standard thoracotomy. The operative field is significantly smaller than with a standard thoracotomy, requiring more time to dissect the mediastinum; however, the pain is less and shoulder range of motion is superior to what is seen after standard thoracotomy during the early postoperative period. We conclude that there is no overall advantage to using the muscle-sparing incision in patients with lung cancer.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1436-2813
    Keywords: lung cancer ; implantation ; drainage tube
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report herein the case of a 70-year-old man in whom a chest wall implantation of adenocarcinoma of the lung at the drainage tube site was found 4 months after a right lower lobectomy with mediastinal lymph node dissection had been performed for adenocarcinoma of the right lower lobe. The lesion was successfully treated by tumor extirpation. We believe that tumor seeding to the chest wall occurred at the time of thoracotomy. To prevent such tumor seeding, the pleural cavity should be washed out routinely with a massive volume of physiological saline solution prior to closure of the chest wall.
    Type of Medium: Electronic Resource
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