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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of agricultural and food chemistry 20 (1972), S. 993-996 
    ISSN: 1520-5118
    Source: ACS Legacy Archives
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of agricultural and food chemistry 24 (1976), S. 56-59 
    ISSN: 1520-5118
    Source: ACS Legacy Archives
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Archives of microbiology 116 (1978), S. 69-75 
    ISSN: 1432-072X
    Keywords: Turnover ; Cardiolipin ; Phosphatidyl ethanolamine ; Phosphatidylinositol mannosides ; Glycerides ; Mycobacterium smegmatis ; Mycobacterium phlei
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The rates of breakdown and renewal of individual lipids in cultures of Mycobacterium smegmatis CDC 46 and Mycobacterium phlei ATCC 354 were investigated by means of a pulse labelling technique using palmitate-1-14C. The results indicated that in growing cultures of both strains phospholipids were broken down, and cardiolipin had a very rapid turnover. In chase experiments, almost 45% and 40% of the radioactivity of this component were lost respectively from M. smegmatis and M. phlei during one generation time of the cell. The other two major components, phosphatidyl ethanolamine and phosphatidylinositol mannosides showed relatively low turnover. The loss of radioactivity from phosphatidylinositol mannosides was greater in M. phlei than in M. smegmatis but the loss of radioactivity from phosphatidyl ethanolamine was higher in M. smegmatis. The pattern of loss of radioactivity from lipids was almost the same in both strains, the difference being only in the extent of loss. The differences in the cellular localization of the phospholipids indicate their different roles within the cell. Results obtained with the glyceride fraction indicated a very rapid turnover of triglycerides in both strains.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 45 (1980), S. 0 
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Variations in levels of adenine nucleotides during growth of A. parusiticus were studied under asparagine and zinc deficiency and correlated with aflatoxin biosynthesis. ATP levels decreased gradually from exponential to stationary phase but the reverse was true for ADP and AMP. However, AMP levels in stationary phase were virtually constant under all growth conditions employed. Increased AMP levels were observed in fungal mycelium on high aflatoxin-producing medium as compared to the deficient media. The onset of aflatoxin biosynthesis however was accompanied by a lowering of energy charge and ATP levels.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 75 (1953), S. 2020-2020 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 207 (1965), S. 869-870 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Female guinea-pigs in groups of four, weighing 350-380 g, were intramuscularly given saline solution of dihydrostreptomycin sulphate (Pfizer) (0-1 g/kg body weight). Guinea-pigs without dihydrostreptomycin served as the controls. After ten days of administration of the drug a saline solution of ...
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 28 (1977), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1438-2385
    Source: Springer Online Journal Archives 1860-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Description / Table of Contents: Summary Zn++, Mg++, and Mn++ ions at certain concentrations, stimulated the incorporation of [1-34C] acetate-into aflatoxins by resting mycelia ofAspergillus parasiticus suspended intris-HC] buffer of pH 7.2. Ba++ gave consistant stimulation over a wide range of concentrations. Ethanol markedly inhibited the incorporation. Of the tricarboxylic acid cycle intermediates, citric acid gave the maximum stimulation.
    Notes: Zusammenfassung Zn++, Mg++ und Mn++-Ionen stimulieren bei gewissen Konzentrationen den Einbau von C14-acetat in Aflatoxinen durch ruhende Mycelien desAspergillus parasitic in tris-HCl-Puffer bei pH 7,2. Ba++ gaben Aktivierungen über einen weiten Konzentrationsbereich, während Äthanol den Einbau verhindert. Von den Intermedärprodukten des 3-Carbonsäure-Cyclus gab die Citronensäure ein Maximum an Aktivierung.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    European food research and technology 154 (1974), S. 201-205 
    ISSN: 1438-2385
    Source: Springer Online Journal Archives 1860-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Description / Table of Contents: Summary The effect of a single dose of aflatoxin B, on the activities of chick liver mitochondrial enzymes, viz., succinate dehydrogenase, malatedehydrogenase and isocitrate dehydrogenase was studied, 24 hours after the administration of the toxin. A drastic reduction in the activities of the above enzymes was observed indicating mitochondrial injury due to aflatoxin toxicity. A significant decrease in the activities of transaminases was noted. A rise in the activities of serum alkaline phosphatase and serum aldolase of chicks together with a decrease in the activities of the liver enzymes are suggestive of impaired liver function in aflatoxin B1 poisoning.
    Notes: Zusammenfassung Der Einfluß einer einzigen Dose von Aflatoxin B1 auf die Aktivität der Kückenleber-Mitochondrien-Enzyme wie Succinat-Dehydrogenase, Malat-Dehydrogenase und Isocitrat-Dehydrogenase wurden 24 Std nach der Verabreichung des Toxins untersucht. Eine drastische Reduzierung der Aktivität der obengenannten Enzyme wurde beodachtet, was einen Mitochondrienschaden durch die Aflatoxin-Toxicitiit anzeigt. Eine signifikante Abnahme in der Aktivität der Transaminasen wurde festgestellt. Ein Anstieg in den Aktivitäten der alkalischen Serum-Phosphatase und der Serum-Aldolase der Kücken, zusammen mit einer Abnahme in den Aktivitäten der Leberenzyme, sind bezeichnend für geschädigte Leberfunktionen durch Aflatoxin B1.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    European food research and technology 156 (1974), S. 72-76 
    ISSN: 1438-2385
    Source: Springer Online Journal Archives 1860-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Description / Table of Contents: Summary Wax esters ofAspergillus flavus ink (DU/KR 79-D) contained palmitic acid, oleic acid and oleyl alcohol as the major components. Maximum incorporation of labelled (1—14C)-acetate into wax esters was observed on the second day of growth (about 19%), while in aflatoxins it was observed on the tenth day, when incorporation into wax esters had decreased considerably. The wax ester hydrolysate contained precursors of aflatoxin B1. One ninth of the radioactivity in aflatoxin was shown to be due to oleic acid. It is postulated that the fungus metabolises wax esters into aflatoxins.
    Notes: Zusammenfassung Wachsester volnAspergillus flavus enthalten Palmitinsäure, Ölsäure und Oleylalkohole als Hauptkomponenten. Das Maximum der Aufnahme von markiertem (1—14C)-acetat in Wachsester wurde vom 2. Tage ab des Wachstums beobachtet (ungefähr 19%), während der Einbau in die Aflatoxine vom 10. Tage ab beobachtet wurde, wenn der Einbau in die Wachsester beträchtlich abnimmt. Die Wachsesterhydrolysate enthalten Vorstufen von Aflatoxin B1. Ein Neuntel der Radioaktivität des Aflatoxins ist auf die Ölsäure zurückzuführen. Es wird daher postuliert, daß der Pilz die Wachsester in die Aflatoxine metaboliert.
    Type of Medium: Electronic Resource
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