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  • 1
    Electronic Resource
    Electronic Resource
    Descriptive anatomy of the human auditory tube (1999)
    Springer
    Surgical and radiologic anatomy 20 (1999), S. 335-340 
    Details
    ISSN: 1279-8517
    Keywords: Auditory tube ; Tubal lumen ; Levator muscle of the soft palate ; Tensor muscle of the soft palate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The aim of this study was to correlate current morphologic data relating to the lumen of the auditory tube. Four methods were used: dissection under the operating microscope; microendoscopy of the tubal lumen; optical and electron microscope histology; and MR or CT imaging. The auditory tube consists of two unequal cones, a small posterior third, fixed and osseous (protympanum), and a mobile fibrocartilaginous anterior two-thirds, both joined by the tubal isthmus, a short constriction which is pseudosphincteric at endoscopy. The tensor veli palatini muscle (TVPM) and the levator veli palatini muscle (LVPM) are the chief muscles that vary the tubal lumen of the fibrocartilaginous portion, which is collapsed at rest. CT and especially MR imaging allows their observation in static conditions. Serial histologic sections reveal the continuity between the TVPM and the tensor tympani muscle. The main cartilage framing the lumen varies in shape according to the level surveyed. The tubal mucosa is lined with an epithelium combining ciliated and mucus cells, involved in mucociliary drainage and gas exchanges in the auditory tube. These morphologic elements represent a basis for study of tubal physiology and for planning treatment in dysfunctions of the auditory tube.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s00276-998-0335-4
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Descriptive anatomy of the human auditory tube (1998)
    Springer
    Surgical and radiologic anatomy 20 (1998), S. 335-340 
    Details
    ISSN: 1279-8517
    Keywords: Auditory tube ; Tubal lumen ; Levator muscle of the soft palate ; Tensor muscle of the soft palate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Ce travail a pour but la confrontation des données morphologiques actuelles concernant la lumière de la trompe auditive (tuba auditiva) ou trompe d'Eustache. 4 méthodes ont été utilisées: la dissection effectuée avec un microscope opératoire, la micro endoscopie de la lumière tubaire, I'histologie en microscopie optique et électronique, I'imagerie par résonance magnétique nucléaire ou tomodensitométrie. La trompe auditive est faite de deux cônes inégaux, I'un petit (1/3) postérieur, fixe et osseux (protympanum), I'autre plus allongé (2/3), mobile fibro-cartilagineux, réunis tous deux par l'isthme tubaire, étranglement court, pseudo-sphinctérien en endoscopie. Le muscle tenseur du voile du palais (MTVP) et le muscle élévateur du voile du palais sont les principaux muscles faisant varier la lumière tubaire de la portion fibro-cartilagineuse, colla∼ée au repos. L'imagerie en TDM et surtout en IRM permet de les observer de façon statique. Les coupes sériées en histologie révèlent la continuité entre le MTVP et le muscle tenseur du tympan. Le cartilage principal, armature de la lumière a une forme variable suivant la hauteur considérée. La muqueuse tubaire est tapissée d'un épithélium associant cellules ciliées et cellules à mucus, participant au drainage muco-ciliaire et aux échanges gazeux de la trompe auditive. Ces éléments morphologiques représentent une base pour l'étude de la physiologie tubaire, et I'orientation thérapeutique des dysfonctions de la trompe auditive.
    Notes: Summary The aim of this study was to correlate current morphologic data relating to the lumen of the auditory tube. Four methods were used: dissection under the operating microscope; microendoscopy of the tubal lumen; optical and electron microscope histology; and MR or CT imaging. The auditory tube consists of two unequal cones, a small posterior third, fixed and osseous (protympanum), and a mobile fibrocartilaginous anterior two-thirds, both joined by the tubal isthmus, a short constriction which is pseudosphincteric at endoscopy. The tensor veli palatini muscle (TVPM) and the levator veli palatini muscle (LVPM) are the chief muscles that vary the tubal lumen of the fibrocartilaginous portion, which is collapsed at rest. CT and especially MR imaging allows their observation in static conditions. Serial histologic sections reveal the continuity between the TVPM and the tensor tympani muscle. The main cartilage framing the lumen varies in shape according to the level surveyed. The tubal mucosa is lined with an epithelium combining ciliated and mucus cells, involved in mucociliary drainage and gas exchanges in the auditory tube. These morphologic elements represent a basis for study of tubal physiology and for planning treatment in dysfunctions of the auditory tube.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01630616
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Ferromagnetic ordering in an organic compound: Di-(2, 2, 6, 6-tetramethyl-4 piperidinol-1 oxyl) (tanol suberate)
    Amsterdam : Elsevier
    Physics Letters A 45 (1973), S. 362-364 
    Details
    ISSN: 0375-9601
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0375-9601(73)90238-7
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Assessment of estrogenic recruitment before chemotherapy in advanced breast cancer: Preliminary results of a double-blind randomized study of the eortic breast cancer cooperative group
    Amsterdam : Elsevier
    The @Journal of Steroid Biochemistry and Molecular Biology 37 (1990), S. 1109-1113 
    Details
    ISSN: 0960-0760
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0960-0760(90)90474-Y
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Polyadenylic–Polyuridylic Acid Plus Locoregional Radiotherapy Versus Chemotherapy with CMF in Operable Breast Cancer: a 14 Year Follow-up Analysis of a Randomized Trial of the Fédération Nationale des Centres de Lutte Contre le Cancer (FNCLCC) (2000)
    Springer
    Breast cancer research and treatment 64 (2000), S. 189-191 
    Details
    ISSN: 1573-7217
    Keywords: adjuvant treatment ; breast cancer ; chemotherapy ; immunotherapy ; radiotherapy ; randomized trial
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract With a median follow-up of 14 years, the combination of polyadenylic–polyuridylic acid plus locoregional radiotherapy (257 patients) has significantly improved disease-free survival (p = 0.03) and significantly reduced the incidence of metastases (p = 0.04) when compared to CMF alone (260 patients), in women with operable breast cancer. The trial does not, however, permit an appreciation of the respective role of radiotherapy and PolyAU in these results.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1006498121628
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  • 6
    Electronic Resource
    Electronic Resource
    Delayed adjuvant tamoxifen: Ten-year results of a collaborative randomized controlled trial in early breast cancer (TAM-02 trial) (2000)
    Springer
    Annals of oncology 11 (2000), S. 515-519 
    Details
    ISSN: 1569-8041
    Keywords: adjuvant treatment ; breast cancer ; tamoxifen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Aim:Immediate adjuvant tamoxifen reduces disease recurrence andimproves survival in patients with early breast cancer. However, is it toolate to administer tamoxifen to patients who have already undergone treatment,but were unable to benefit from this adjuvant therapy? The French NationalCancer Centers (FNCLCC) have investigated the efficacy of delayed tamoxifenadministration in a randomized controlled trial. Patients and methods:From September 1986 to October 1989, womenwith primary breast cancer, who had undergone surgery, radiotherapy, and/orreceived adjuvant chemotherapy but not hormone therapy more than two yearsearlier, were randomized to receive either 30 mg/day tamoxifen or notreatment. The 10-year disease-free and overall survival rates of the twogroups of patients and of various subgroups were determined according to theKaplan–Meyer method and compared by the log-rank test. Results:This intention-to-treat analysis comprised 250 women inthe tamoxifen group and 244 in the control group. Patient characteristics(age, T stage, number of positive nodes, receptor status, and interval sincetumor treatment) were comparable in both groups. Delayed adjuvant tamoxifensignificantly improved overall survival only in node-positive patients and inpatients with estrogen receptor-positive (ER+) or progesteronereceptor-positive (PR+) tumors. Disease-free survival, however, wassignificantly improved in the global population and in several patientsubgroups (node-positive, ER+, PR+). Patients in whom the interval betweenprimary treatment and delayed adjuvant tamoxifen was greater than five yearsalso had significantly improved disease-free survival. Conclusions:Overall and disease-free survival results indicatethat delayed adjuvant tamoxifen administration (30 mg/day) is justified inwomen with early breast cancer, even if this treatment is initiated two ormore years after primary treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008321415065
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    Paper (German National Licenses)
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