ISSN:
1573-6776
Source:
Springer Online Journal Archives 1860-2000
Topics:
Process Engineering, Biotechnology, Nutrition Technology
Notes:
Summary The addition of 4% (v/v) dimethyl sulfoxide (DMSO) increased the total production of heavy chain monoclonal antibody (HC MAb) in suspension culture of genetically modified Nicotiana tabacum by three fold. This may be due to stabilization of HC MAb in the presence of DMSO by forming hydrogen bonds with proton-donor groups on protein molecules.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00132011
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