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  • 1
    Electronic Resource
    Electronic Resource
    Therapeutic results in cryptorchidism after combination therapy with LH-RH nasal spray and hCG (1987)
    Springer
    European journal of pediatrics 146 (1987), S. S31 
    Details
    ISSN: 1432-1076
    Keywords: Cryptorchidism ; Hormonal treatment ; Combined LH-RH/hCG therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Seventy-two boys with 81 cryptorchid testes were treated with combined LH-RH nasal spray and hCG in the period between 1983 and 1985. Cryptocur (LH-RH) was applied as nasal spray at a dose of 1.2 mg daily over a period of 14 days. In all of the patients, hCG treatment was carried out subsequently according to the WHO guidelines with five intramuscular injections at 2-day intervals. Primary treatment results considerably improved using the regimen. The rate of complete descent was 86.4% at the end of therapy and later dropped to 70.6% after 2 years follow-up. These results support the experience of Hadziselimovic et al. with this combined treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00452866
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  • 2
    Electronic Resource
    Electronic Resource
    A 7-year-old child with primary tumour localisation in the distal duodenum – new imaging procedures for an improved diagnosis (1997)
    Springer
    European journal of pediatrics 156 (1997), S. 568-571 
    Details
    ISSN: 1432-1076
    Keywords: Key words Metastatic duodenal gastrinoma ; Childhood ; Somatostatin receptor scintigraphy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Duodenal gastrinomas in childhood are extremely rare and often missed at first medical consultation. We report on a 7-year-old child with sporadic gastrinoma of primary localisation in the distal duodenum. Small metastases in the liver and regional nodes were detected pre-operatively by somatostatin receptor scintigraphy (SRS) but not by other conventional imaging procedures. Diagnostic procedures include pre-operative SRS, endoscopic ultrasound and intra-operative endoscopic transillumination. Conclusion Gastrinomas are rare abdominal tumours in childhood. Pre-operative tumour-specific diagnosis is possible by 111indium pentreotide SRS.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004310050665
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  • 3
    Electronic Resource
    Electronic Resource
    The results of 9 years of experience with a combined treatment with LH-RH and HCG for cryptorchidism (1993)
    Springer
    European journal of pediatrics 152 (1993), S. S34 
    Details
    ISSN: 1432-1076
    Keywords: Crytorchidism ; Hormonal treatment ; Combination LH-RH/HCG therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract During a period of time between 1984 and 1986, 79 boys with 91 cryptorchid testes were treated with a therapy which combined a LH-RH nasal spray followed by HCG. Kryptocur (LH-RH) was admininistered as a nasal spray at a dosage of 1.2 μg daily for a period of 14 days. HCG was injected intramuscularly, 5 times at 2-day intervals. The dosage was one-half the amount recommended by the WHF. This particular therapeutic strategy was more efficacious than those used previously. During the follow-up seven years later, 50.5% of the testes were in a scrotal position. The results during a five year follow-up of a second study were similar to those observed in the earlier study: 67% of the cryptorchid testes were in the scrotum.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02125434
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  • 4
    Electronic Resource
    Electronic Resource
    Qualitative and quantitative analysis of synapses in Hirschsprung's disease (1998)
    Springer
    Pediatric surgery international 13 (1998), S. 468-473 
    Details
    ISSN: 1437-9813
    Keywords: Key words Hirschsprung's disease ; Synapses ; Acetylcholinesterase ; Synaptophysin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In Hirschsprung's disease (HD), certain intestinal nervous plexuses are absent. Sprouting nerve endings contain different amounts of synaptophysin (SY), a protein and main constituent of acetylcholinesterase (AChE) storage compartments. Due to the lack of specific markers for synapses, a qualitative analysis of nerve endings of intestinal segments affected by HD has not yet been undertaken. For this study, resected colorectal specimens from patients with HD (n= 8, mean age 2.1 years) were investigated in parallel for AChE, SY, and content of small synaptic vesicles by biochemical, immunohistochemical, and electronmicroscopic means. In the microdissected muscular layer, reduced SY (1.4 μg/mg total protein, normal 24 ± 0.3) was observed. Immunohistochemistry showed in affected tissues reduced numbers of SY-positive nerve fibers and nerve endings, which in turn were thickened and distorted, in both the muscle proper and the muscularis mucosae. Combining both morphologic and biochemical findings, in HD the number of cholinergic vesicles in the remaining nerve endings seems to be increased as measured by SY, a marker molecule specific for synaptic vesicles. Our data also suggest that nerve endings in HD may contain high concentrations of cholinergic vesicles, paralleling the known high amounts of acetylcholine and␣AChE found in intestinal segments of patients with HD.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003830050376
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  • 5
    Electronic Resource
    Electronic Resource
    219. Der autologe Venenbypass als Operation der Wahl bei chronischen arteriellen Gefäßverschlüssen (1971)
    Springer
    Langenbeck's archives of surgery 329 (1971), S. 853-853 
    Details
    ISSN: 1435-2451
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Seit 1964 wird in der Chirurgischen Klinik der Freien Universität Berlin die autologe Venenumkehrplastik zur Überbrückung peripherer arterieller Gefäßverschlüsse bevorzugt. An Hand von histologischen und angiografischen Verlaufsbeobachtungen sowie Untersuchungen mit elektromagnetischen Blutströmungsmeßgeräten konnte die gute Einheilung der arterialisierten Venentransplantate und deren positive Anpassungsvorgänge nachgewiesen werden. Die eigenen Erfahrungen stützen sich auf 573 Venenbypässen, von denen 523 im Bereich der unteren Extremitäten angelegt worden sind. Eine Thrombosierung trat in 16,3% ein. Dabei war die Anzahl der Sofortthrombosen mit 8,1% am höchsten. Die anderen Komplikationen — wie Nachblutungen, Sekundärheilungen, Anastomosenaneurysmen und Wundrandnekrosen — waren sehr viel seltener. Auf Grund der guten Spätergebnisse wird der autologe Venenbypass als ein leistungsfähiges Operationsverfahren für die Behandlung peripherer arterieller Gefäßverschlüsse empfohlen.
    Notes: Summary Since 1964, the autologous reversed vein graft operation for bridging peripheral arterial occlusions has been preferred at the Surgical Clinic of the Free University, Berlin. Aided by histological and angiographic control examinations as well as examinations with electro-magnetic instruments for circulatory measurements, we were able to demonstrate the satisfactory lodgement of the arterialized venous transplant and its positive functional adaptation. Our own experience is based on 573 venous by-pass operations, of which 523 were in the legs. Thrombosis occurred in 16.3%. The number of immediate (intraoperative) thromboses was 8.1% at the most. Other complications, such as late haemorrhages, secondary healing, anastomotic aneurysms and wound necrosis were much more rare. In view of the good late results the autologous venous by-pass is recommended as an effective surgical treatment of peripheral arterial occlusion.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01770649
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  • 6
    Electronic Resource
    Electronic Resource
    304. Die Nahtinsuffizienz an der Oesophagusanastomose (1971)
    Springer
    Langenbeck's archives of surgery 329 (1971), S. 1119-1120 
    Details
    ISSN: 1435-2451
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bericht über 440 Patienten, bei denen eine Gastrektomie oder Kardiaresektion durchgeführt wurde. 57 (12,9%) Kranke verstarben an einer Nahtinsuffizienz der Oesophagusanastomose. Klinik, Diagnostik und Therapie der Nahtinsuffizienz werden diskutiert. An erster Stelle steht die konservative Behandlung. Unter 71 Patienten trat bei 15 eine Nahtinsuffizienz auf, davon überlebten 10 Kranke. Durch Verbesserung der Nahttechnik konnte die Quote der tödlichen Nahtinsuffizienzen von 13,6% auf 8,4% gesenkt werden.
    Notes: Summary This is a report on 440 patients who underwent gastrectomy or resection of the cardia. Of these 57 (12.9%) died as a result of a suture insufficiency of the oesophageal anastomosis. Clinical features, diagnosis and treatment of the suture insufficiency are discussed. In the first place conservative treatment has to be tried. Amongst 71 patients a suture insufficiency occurred in 15 and 10 of these patients survived. By improving our suturing technique we were able to improve the rate of fatal suture insufficiencies from 13.6% to 8.4%.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01770737
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  • 7
    Electronic Resource
    Electronic Resource
    97. Extrahepatischer Verschlußikterus bei 3 Säuglingen bzw. Neugeborenen durch einen dem Mirizzi-Syndrom gleichenden Befund (1981)
    Springer
    Langenbeck's archives of surgery 355 (1981), S. 508-509 
    Details
    ISSN: 1435-2451
    Keywords: Bile duct occlusion ; Mirizzi syndrome ; Bile duct atresia ; Omentoportoduodenopexy ; Verschlußikterus ; Mirizzi-Syndrom ; Gallengangsatresie ; Omentoportoduodenopexie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es wird über 3 Kinder berichtet, die wegen eines Verschlußikterus laparotomiert worden sind. Der Ikterus war, wie beim Mirizzi-Syndrom, durch eine Kompression der Gallenwege verursacht worden. Das Infundibulum war auf den D. chol. bzw. auf den D. hepat. gedrückt worden. Bei keinem der Kinder war ein Konkrement nachzuweisen. Der Hartmann-Pouch war lediglich durch eine Anomalie des D. cysticus und durch Verwachsungen in dieser Weise fixiert. Alle 3 Kinder konnten durch Cholecystektomie bzw. Choledocholyse und Omentoportoduodenopexie geheilt werden.
    Notes: Summary The cases of three children are reported (6 days, 5 weeks, and 3 years old) with occlusion of the extrahepatic bile ducts due to compression of the ductus choledochus or ductus hepaticus communis through Hartmann's pouch, like the Mirizzi syndrome. The Hartmann pouch was medially disposed and fixed in this position through adhesions. In two cases the intrahepatic bile ducts were completely obliterated as in bile duct atresia. The children were cured with cholecystectomy, adhesiolysis, and omentoportoduodenopexy. The children are well 1 – 7 years after the operation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01286926
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  • 8
    Electronic Resource
    Electronic Resource
    291. Die extrakorporale Perfusion mit Pavianleber bei akutem Leberversagen (1979)
    Springer
    Langenbeck's archives of surgery 349 (1979), S. 623-623 
    Details
    ISSN: 1435-2451
    Keywords: Liver perfusion ; Hepatic coma ; Leberperfusion ; Leberkoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Seit 1968 haben wir 19 Leberperfusionen bei 11 Patienten mit insgesamt 16 Komaepisoden durchgeführt. Bei 7 Patienten besserte sich nach der Perfusion der neurologische Status. Das Bewußtsein bei 5 von diesen 7 Patienten war völlig ungetrübt. 6 Patienten überlebten mehr als 4 Tage nach der Perfusion. 2 von diesen 6 Patienten konnten geheilt entlassen werden. Anhand eines Beispiels wurden die Indikation, das Behandlungsprinzip, die Technik der extrakorporalen Leberperfusion und die Ergebnisse verschiedener Autoren dargestellt.
    Notes: Summary Since 1968 we have performed 19 extracorporeal liver perfusions for the treatment of 16 episodes of hepatic coma in 11 patients. Neurological improvement was noted in 7 patients. 5 of these 7 patients recovered full consciousness. 6 patients lived more than 4 days after perfusion, 2 of them made complete recovery and are alive. The indication, principle and the technique of the extracorporeal liver perfusion are illustrated and the results of other authors were summarized.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01729752
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  • 9
    Electronic Resource
    Electronic Resource
    97. Die chirurgische Problematik mit den angeborenen Passagestörungen des Duodenus im Säuglingsalter (1980)
    Springer
    Langenbeck's archives of surgery 352 (1980), S. 337-337 
    Details
    ISSN: 1435-2451
    Keywords: Duodenal ileus ; Megaduodenum ; Intestinal atresia ; Malrotation ; Duodenalileus ; Megaduodenum ; Darmatresie ; Malrotation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Ein Duodenalileus kann erhebliche operative Schwierigkeiten bereiten. An Hand von 69 operierten Kindern mit Duodenalileus wird die Problematik dargelegt. Es wird darauf verwiesen, daß intestinale Begleitmißbildungen (Oesophagus-, Enddarmatresie, Malrotation usw.) in der gleichen Sitzung zu korrigieren sind. Auch sind die zahlreichen Anomalien der Gallengänge, die Mehrfachatresien des Duodenums mit dem Windsock-Phänomen und die Probleme bei einem Megaduodenum zu beachten. Nur detaillierte Kenntnisse über dieses Krankheitsbild können den Operateur vor Irrtümern bewahren.
    Notes: Summary The operative correction of duodenal occlusion is often difficult. From 1972 to 1980 we operated on 69 children with duodenal occlusion in our hospital. There are two main problems: first, the general difficulties, especially if other malformations are present. We treat esophageal atresia, rectal malformation, and malrotation of the midgut simultaneously. Second, there are many local problems: multiple atresia of the duodenum, the wind sock web, anomalies of the choledochus duct, and difficulties with the primary duodenum. These problems are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01292058
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  • 10
    Electronic Resource
    Electronic Resource
    184. Die Behandlung des Leberkomas mit Hilfe der heterologen Leberperfusion (1969)
    Springer
    Langenbeck's archives of surgery 325 (1969), S. 1123-1128 
    Details
    ISSN: 1435-2451
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die wichtigste Indikation für die Behandlung des Leberkomas mit Hilfe der heterologen Leberperfusion ist das Leberzerfallskoma (Intoxikation, Hepatitis). Bei 3 Patienten wurde das Verfahren in Kombination mit der Austauschstransfusion angewandt. Einer dieser Patienten mit einer Hepatitis wurde erfolgreich behandelt. Die technische Durchführung der Perfusion und die Kriterien für die Beurteilung der Funktionsfähigkeit der Schweineleber werden diskutiert.
    Notes: Summary The principal indication for the treatment of hepatic coma with heterologous liver perfusion is the liver disintegration coma (intoxication, hepatitis). In 3 patients the method was used in combination with exchange transfusion. One of these patients with hepatitis was treated successfully. The technique of perfusion and the criteria for the assessment of functional capacity of pig's liver are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01256082
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