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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European radiology 10 (2000), S. 1073-1075 
    ISSN: 1432-1084
    Keywords: Key words: Meningeal hemangiopericytoma – MR imaging – Single photon emission computed tomography – CT – Childhood
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Meningeal hemangiopericytoma (MHP) is extremely rare in childhood. Mean age at diagnosis is between 38 and 43 years. We present an 8-year-old boy with MHP of the middle cranial fossa. Imaging findings were indistinguishable from an aggressive bone tumor such as Ewing's sarcoma. Imaging findings are presented and discussed. Our case indicates that MHP should be considered in the differential diagnosis of skull-base tumors despite the fact that MHP is extremely rare in childhood.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1076
    Keywords: Hyper-IgE-syndrome ; Multiple liver abscesses ; Percutaneous needle aspiration ; Oral chloramphenicol
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In a patient with Hyper-IgE-syndrome multiple liver abscesses developed in spite of prophylactic treatment with trimethoprim and sulfamethoxazol. Ultrasound confirmed the clinical diagnosis and percutaneous needle aspiration under ultrasonographic guidance and culture of the aspirated pus allowed specific antibiotic treatment by oral chloramphenicol alone without surgical drainage. The isolated Staph. aureus strain was resistant to trimethoprim and sulfamethoxazol.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1076
    Keywords: Transdermal oestradiol ; Induction of puberty ; Hypogonadal girls ; Turner syndrome ; Serum E1 and E2
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Transdermal 17β-oestradiol administration (17β-E2), used mainly in menopausal women, allows a continuous 17β-E2 delivery through the skin into the systemic circulation, avoiding intestinal and hepatic passage. In order to explore whether transdermal 17β-E2 could be used for the induction of puberty, 17β-E2 patches with low dose delivery were administered in nine prepubertal girls with Turner syndrome (bone age 〉10.5 years) for a mean period of 2.2 years. Treatment schedule: 5 μg/day for 6–9 months, 10 μg/day for 6–9 months, 25 μg/day for long-term substitution; addition of cyclic gestagen p.o. after 18–24 months. Breast development started within 3 months of therapy and menstruation occurred after 2 years. Growth rate increased from 3.2 to 5.0 cm/year during the 1st year of therapy, height prediction did not change. Serum oestradiol (E2) and urinary E2 conjugates increased proportionally with 17β-E2 doses, serum oestrone (E1) rose much less. The possibility to imitate time course, clinical events and hormonal changes of normal puberty, the absence of adverse drug reactions and the excellent acceptance and easy mode of application suggest that transdermal 17β-E2 is optimally suited for hormonal substitution in girls with hypogonadism.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 151 (1992), S. 564-568 
    ISSN: 1432-1076
    Keywords: Colour Doppler sonography ; Ductus venosus Arantii ; Hepatic encephalopathy ; Hypergalactosaemia ; Newborn screening ; Portosystemic shunting
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Hypergalactosaemia was discovered in a newborn girl during routine metabolic screening. Hereditary enzyme deficiency was ruled out. Because hypergalactosaemia persisted, an open ductus venosus Arantii was suspected but remained undetected by conventional two-dimensional ultrasonography. It was demonstrated by combined colour and pulsed wave Doppler sonography. At age 3 years 6 months, the girl developed initial symptoms of portosystemic encephalopathy which progressed and was treated by protein restriction, oral lactulose and flumazenil, with some success. In the absence of enzyme deficiency, hypergalactosaemia in the newborn is an early sign of duct persistence. For the unambiguous diagnosis of an open duct, colour Doppler sonography is the method of choice. Pulsed wave Doppler sonography is recommended for pathophysiological characterisation of the splanchnic venous return.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 151 (1992), S. 54-56 
    ISSN: 1432-1076
    Keywords: Congenital rickets ; Pregnancy ; Phosphorus ; Cathartics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We present a case of antenatal failure of bone growth and mineralisation in a newborn whose anorectic mother repeatedly administered hypertonic phosphate enemas during pregnancy. Phosphate overload in pregnant women appears to impede calcification of the fetal skeleton.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 151 (1992), S. 95-97 
    ISSN: 1432-1076
    Keywords: B cell lymphoma ; Adolescence ; Antineoplastic agents, combined ; Thymus hyperplasia ; Tomography, X-ray, computed
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: abstract Four months after termination of successful chemotherapy for epipharyngeal B-non-Hodgkin lymphoma, an enlarging anterior mediastinal mass was discovered in a 15-year-old boy. There was no other suspicion of tumour recurrence. A simple thymic rebound was likely and a conservative management was chosen. Follow up for more than 12 months was uneventful. The frequency of thymic hyperplasia after termination of chemotherapy is discussed. It is a benign immunological rebound phenomenon and does not require operative intervention.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 156 (1997), S. 719-722 
    ISSN: 1432-1076
    Keywords: Key words Intrahepatic haemangioma ; Portosystemic venous shunting ; Hypergalactoseamia of the newborn ; Hyperammonaemia ; Newborn screening
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Hypergalactosaemia was found in 4 day-old boy during newborn screening. He had no enzyme deficiency but an intrahepatic vascular malformation permitting significant portosystemic venous shunting. The shunt caused hyperammonaemia, accentuated after meals, alimentary hyperglycaemia and hypergalactosaemia, and excess excretion of lactic, 3-hydroxy butyric and other organic acids in urine. Portal venous flow was unimpaired. The vascular anomaly regressed during the first 7 months of life. At this age, full tolerance to lactose-containing cows milk formula was evidenced by the normalization of pre- and postprandial blood glucose, ammonia and galactose, and closure of the shunt was confirmed by ultrasonography. This is one of the few observations of congenital intrahepatic venous shunt regressing spontaneously during infancy. Conclusion A congenital intrahepatic portosystemic venous shunt can cause hypergalactosaemia in the newborn and hyperammonaemia in the small infant. The malformation may resolve spontaneously obviating the need for intervention.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 158 (1999), S. 923-928 
    ISSN: 1432-1076
    Keywords: Key words Hip joint ; Arthritis ; Infection ; Ultrasound ; Laboratory techniques and procedures
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Children with a painful hip present a diagnostic challenge since clinical differentiation between septic arthritis, transient synovitis and Perthes disease may be difficult. Septic arthritis, a potentially life-threatening and debilitating medical emergency, requires early recognition for successful treatment, while transient synovitis and Perthes disease may be managed conservatively. An “ideal” single test for discrimination between these conditions is currently not available. We assessed the value of clinical examination and simple laboratory tests together with radiography and hip ultrasound in differentiating septic arthritis from transient synovitis and Perthes disease by analyzing the records of 89 children treated at our institution for hip pain. Ultrasound, radiographs, laboratory, clinical, and follow-up data were available for all the children. Diagnoses were made according to established criteria. Transient synovitis was present in 64 patients, septic arthritis in 8 (of whom 2 had additional osteomyelitis), and Perthes disease in 4. All children with septic arthritis had hip effusion shown by ultrasound and at least two of the following criteria: fever, elevation of erythrocyte sedimentation rate (ESR) and of C-reactive protein (CRP). None of the children without effusion on ultrasound or who lacked two or all criteria had septic arthritis. Radiographs had no significant impact on the decision-making in primary evaluation of acute hip pain. Conclusion We conclude that investigation of painful hips in children, based on hip ultrasound, body temperature, ESR and CRP, may allow cases for hip joint aspiration to be selected efficiently and may reduce the number of radiographs and hospital admissions.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Pediatric surgery international 13 (1998), S. 197-199 
    ISSN: 1437-9813
    Keywords: Key words Renal tumor ; Cystic nephroma ; Multilocular renal cyst ; Child
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report two boys aged 1 year and 2 years 2 months, respectively, with cystic nephromas. Both presented with a painless abdominal mass. Computed tomography showed a homogeneous, multicystic tumor of the lower pole of the kidney in both cases with thin septa without solid parts. Macroscopically, the surface of the tumor was smooth. Both patients underwent a renal-sparing procedure; histology confirmed the diagnosis of cystic nephroma.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1432-1920
    Keywords: Vein of Galen malformation ; Arteriovenous malformation ; Cerebral atrophy ; Magnetic resonance imaging ; Newborn
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We report a full-term newborn girl with a giant vein of Galen malformation and extreme cerebral atrophy of prenatal origin. She presented on the 3rd day of life with intractable congestive heart failure. The diagnosis of the vascular malformation was confirmed by ultrasound and magnetic resonance imaging.
    Type of Medium: Electronic Resource
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