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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Molecular genetics and genomics 193 (1984), S. 322-326 
    ISSN: 1617-4623
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The activity of the λP gene product at various multiplicities of infection (m.o.i.) was examined in C 1 - conditions using an assay which measures the disappearance of the rapidly-sedimenting closed-circular (c.c) form of phage DNA. When cells were infected with λC1857 at multiplicities of 5 phage/cell or less, between 65%–75% c.c. DNA was lost during incubation. If the multiplicity of infection was increased to 10 phage/cell or greater, a marked inhibition in the cleavage of c.c. DNA was observed. When bacteria were infected with either λCI857CII2002 or λCI857cro27 at low m.o.i., the usual 65%–75% decrease in the percentage of c.c. phage DNA occurred during incubation. In contrast, no losses in c.c. DNA were noted after infection with λCI857cro27susP3. At high m.o.i., the cleavage of c.c. DNA was inhibited after infection with λCI857CII2002, but not after infection with λCI857cro27. It is concluded that at high m.o.i. in C 1 - infections, the expression of gene P is unaffected by the CII gene product, but is inhibited by the increased intracellular levels of cro protein.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 72 (1998), S. 43-49 
    ISSN: 0730-2312
    Keywords: tumor suppression ; p53 ; angiogenesis ; signal transduction ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Tumor suppressors act along diverse biochemical pathways to function as safeguards against cancer. This review summarizes how these pathways can be regulated, primarily by focusing on the well-characterized wild-type p53 tumor suppressor as a paradigm. Specifically, we discuss recent data linking p53 to the processes of signal transduction and angiogenesis. J. Cell. Biochem. Suppls. 30/31:43-49, 1998 © 1998 Wiley-Liss, Inc.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 3
    Electronic Resource
    Electronic Resource
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 64 (1997), S. 343-352 
    ISSN: 0730-2312
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: No abstract.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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