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  • Articles: DFG German National Licenses  (38)
  • 1965-1969  (38)
Source
  • Articles: DFG German National Licenses  (38)
Material
Years
Year
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Annals of hematology 13 (1966), S. 318-327 
    ISSN: 1432-0584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Annals of hematology 12 (1965), S. 52-60 
    ISSN: 1432-0584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 47 (1969), S. 1327-1328 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary A new in vitro method for estimating DNA synthesis times of human bone marrow cells is described.14C-thymidine incorporation rates under amethopterin are determined in individual cells by means of quantitative autoradiography. The method has been established and checked in rat bone marrow as a model.
    Notes: Zusammenfassung Es wird eine neue in vitro-Methode beschrieben zur Bestimmung der DNS-Synthesezeit menschlicher Knochenmarkzellen. Dazu wird die14C-TdR-Einbaugeschwindigkeit unter Amethopterin durch quantitative Einzelzell-autoradiographie bestimmt. Das Verfahren wird entwickelt und geprüft am Modell des Rattenknochenmarks.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 44 (1966), S. 334-337 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary In the terminal stage of a chronic myelogenous leukemia with osteomyelosclerosis cytogenetic and autoradiographic studies of the chromosomes disclosed hyperdiploidia of 48 chromosomes with 2 Philadelphia chromosomes, one probable isochromosome 17 and one extrachromosome of group no. 6 to 12. The importance of the chromosome findings and their relation with the hematological and clinical findings are discussed.
    Notes: Zusammenfassung Bei einer chronischen myeloischen Leukämie mit Osteomyelosklerose konnte in der terminalen Phase mit Hilfe der cytogenetischen und autoradiographischen Untersuchung der Chromosomen eine Hyperdiploidie von 48 Chromosomen mit zwei Philadelphia-Chromosomen, einem wahrscheinlichen Isochromosom 17 und einem Extrachromosom der Gruppe Nr. 6–12 nachgewiesen werden. Die Bedeutung der Chromosomenbefunde und ihr Zusammenhang mit den hämatologischen und klinischen Befunden werden diskutiert.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary The microscope-photometer with variable measuring diaphragm (MPV) is used for the automatic counting of silver grains in quantitative autoradiography, and is tested as to its possibilities and limits. Measuring was considerably faster than visual counting and its error limit is lower with approximately 6%. It is possible to measure individual cells, which, however, must not lie too close each other. But measuring of nucleoli in labelled nuclei harbours considerable sources of error due to the action of the Schwarzschild-Villiger effect.
    Notes: Zusammenfassung Das Mikroskop-Photometer mit variabler Meßblende (MPV) wird für die automatische Silberkornzählung in der quantitativen Autoradiographie eingesetzt und auf seine Möglichkeiten und Grenzen geprüft. Die Messung erfolgt bedeutend schneller als die visuelle Zählung und hat mit rund 6% eine geringere Fehlergrenze. Es ist möglich, einzelne Zellen zu messen, die allerdings nicht zu dicht nebeneinander liegen dürfen. Dagegen ist die Messung von Nucleoli in markierten Zellkernen durch die Auswirkung des Schwarzschild-Villiger-Effektes mit großen Fehlermöglichkeiten behaftet.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 46 (1968), S. 277-278 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary 5 different antibody specificities can be differentiated in heterologous antilymphocytic antiserum of the rabbit: 1 anti-erythrocyte/leukocyte/thrombocyte/liver/kidney antibody. 2 anti-leukocyte/thrombocyte/liver/kidney antibody. 3 anti-leukocyte antibody. 4 anti-erythrocyte antibody. 5 anti-serumprotein antibody. Anti-erythrocyte and anti-leukocyte antibodies were found in the 19 S and 7 S globulin fraction, whereas antibodies directed against an antigen common to erythrocytes and leukocytes could only be demonstrated in the 7 S fraction. The practical implications of this latter type of antibody were discussed. No blood group specificity was demonstrated. The crossreactivity of anti mousecell antibodies with blood cells of the rat did not include all the antibodies in the antiserum.
    Notes: Zusammenfassung Im heterologen Anti-Mäuse- bzw.-Rattenlymphocytenserum von Kaninchen ließen sich die folgenden Antikörpertypen differenzieren: 1 Anti-Erythrocyten/Leukocyten/Thrombocyten/Leber/Nierenantikörper. 2 Anti-Leukocyten/Thrombocyten/Leber/Nierenantikörper. 3 Anti-Leukocytenantikörper. 4 Anti-Erythrocytenantikörper. 5 Anti-Serumproteinantikörper. Während anti-erythrocytäre und anti-leukocytäre Antikörper sowohl in der 7 S als auch in der 19 S Fraktion auftraten, wurden Antikörper, die gegen ein den Erythrocyten und Leukocyten gemeinsames Antigen gerichtet sind, nur in der 7 S-Fraktion nachgewiesen. Die Bedeutung des letzteren Antikörpertyps, insbesondere für die Absorption der Erythrocytenagglutine wird diskutiert. Neben dem Fehlen der Gruppenspezifität wird gezeigt, daß die Kreuzreaktion mit Rattenblutzellen auf einen Teil der Antikörper beschränkt ist.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Histochemistry and cell biology 8 (1966), S. 1-8 
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Zusammenfassung Auf Grund abgestufter Lichtschwärzungen an Strippingfilm-Präparaten wird ermittelt, daß bis zu einer Zahl von rund 70 Silberkörnern pro 10 μ2-Fläche eine quantitative auflichtphotometrische Silberkornzählung möglich ist. An den Basalzellen des Vormagens der Maus wird nach 3H-Thymidin-Gabe das Verhältnis von vorhandener und zu erwartender Silberkornzahl in Abhängigkeit von der Expositionszeit ermittelt. Daraus ergibt sich der Koinzidenz-Koeffizient in Abhängigkeit von der Silberkorndichte. Es wird darauf hingewiesen, daß bei größeren Silberkorndichten und bestimmten quantitativ-autoradiographischen Fragestellungen die Koinzidenz der β-Teilchen zu berücksichtigen ist.
    Notes: Summary Based on tests with graduated light densities on stripping film preparations it is shown that up to a number of approximately 70 silver grains/10 μ2 a quantitative determination of the silver grains is possible by incident light microscopy. The proportion of the number of silver grains present to the number of silver grains to be expected in relation to the exposure time is determined on the basal cells of the forestomach in mice after the administration of 3H-thymidine. The result is a coincidence-coefficient which depends on the silver grain density. It is pointed out that in cases of a high silver grain density and in certain quantitative autoradiographic problems the coincidence of β-corpuscles has to be taken into consideration.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Annals of hematology 14 (1966), S. 176-182 
    ISSN: 1432-0584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Annals of hematology 14 (1967), S. 238-248 
    ISSN: 1432-0584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Annals of hematology 14 (1967), S. 295-314 
    ISSN: 1432-0584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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