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  • Artikel: DFG Deutsche Nationallizenzen  (9)
  • Bombyx mori  (5)
  • Abnormal tau  (2)
  • Lewy body  (2)
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  • Artikel: DFG Deutsche Nationallizenzen  (9)
Materialart
Erscheinungszeitraum
Schlagwörter
  • 1
    Digitale Medien
    Digitale Medien
    Induction of a hemagglutinating activity in the hemolymph of the silkworm, Bombyx mori, infected with cytoplasmic polyhedrosis virus
    Amsterdam : Elsevier
    Journal of Invertebrate Pathology 54 (1989), S. 112-116 
    Details
    ISSN: 0022-2011
    Schlagwort(e): Bombyx mori ; cytoplasmic polyhedrosis virus ; hemagglutinating activity
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Biologie
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1016/0022-2011(89)90147-X
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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    Artikel (Nationallizenzen)
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  • 2
    Digitale Medien
    Digitale Medien
    Prothoracicotropic hormone is released five times in the 5th-larval instar of the silkworm, Bombyx mori
    Amsterdam : Elsevier
    Journal of Insect Physiology 39 (1993), S. 83-88 
    Details
    ISSN: 0022-1910
    Schlagwort(e): Bombyx mori ; Ecdysone ; Prothoracicotropic hormone
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Biologie
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1016/0022-1910(93)90021-I
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  • 3
    Digitale Medien
    Digitale Medien
    Stimulation of acid protease activity in the isolated pupal abdomens of the silkworm, Bombyx mori, infected with nuclear polyhedrosis virus
    Amsterdam : Elsevier
    Journal of Invertebrate Pathology 46 (1985), S. 202-204 
    Details
    ISSN: 0022-2011
    Schlagwort(e): Bombyx mori ; acid protease, stimulation of ; isolated pupal abdomen ; nuclear polyhedrosis virus
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Biologie
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1016/0022-2011(85)90151-X
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    Difference of proteins from inclusion bodies formed in the nucleus and cytoplasm of the cytoplasmic polyhedrosis virus-infected midgut in the silkworm, Bombyx mori
    Amsterdam : Elsevier
    Journal of Invertebrate Pathology 50 (1987), S. 26-32 
    Details
    ISSN: 0022-2011
    Schlagwort(e): Bombyx mori ; amino acid sequence ; cytoplasmic polyhedrosis virus ; inclusion body protein
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Biologie
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1016/0022-2011(87)90141-8
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  • 5
    Digitale Medien
    Digitale Medien
    Progressive supranuclear palsy with Lewy bodies (1986)
    Springer
    Acta neuropathologica 71 (1986), S. 344-346 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Progressive supranuclear palsy ; Lewy body ; Parkinson's disease
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary An autopsy case is reported which revealed not only clinical and neuropathological features of progressive supranuclear palsy, but also the presence of large numbers of Lewy bodies in the brain stem nuclei and cerebral cortex. This case seems to be progressive supranuclear palsy with Lewy bodies distributed as in Parkinson's disease. Such case has not been previously reported.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00688061
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  • 6
    Digitale Medien
    Digitale Medien
    Biological activity of enantiomerically pure forms of insect juvenile hormone I and III inBombyx mori (1990)
    Springer
    Cellular and molecular life sciences 46 (1990), S. 220-221 
    Details
    ISSN: 1420-9071
    Schlagwort(e): Juvenile hormone ; enantiomer ; biological activity ; Bombyx mori ; allatectomy
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary Biological activity of enantiomerically pure juvenile hormones was assayed by topical application on allatectomizedBombyx fourth instar larvae. JHs tested were (10R)-JH I [methyl (2E,6E,10R,11S)-10,11-epoxy-3,11-dimethyl-7-ethyl-2,6-tridecadienoate], (10S)-JH I [methyl (2E, 6E, 10S, 11R)-10,11-epoxy-3,11-dimethyl-7-ethyl-2,6-tridecadienoate], (10R)-JH III [methyl (2E,6E,10R)-10,11-epoxy-3,7,11-trimethyl-2,6-dodecadienoate] and (10S)-JH III [methyl (2E,6E,10S)-10,11-epoxy-3,7,11-trimethyl-2,6-dodecadienoate]. Among these compounds, natural (10R)-JH I was most active and the dose needed to induce 50% larval molting was 0.04 μg/larva; it was approximately 12,000 times more active than unnatural (10S)-JH I. Though natural (10R)-JH III showed slight biological activity, it was only one three-thousandth of that of (10R)-JH I. Unnatural (10S)-JH III exhibited no biological activity at the levels assayed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02027321
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  • 7
    Digitale Medien
    Digitale Medien
    Lewy bodies are ubiquitinated (1988)
    Springer
    Acta neuropathologica 75 (1988), S. 345-353 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Lewy body ; Immunocytochemistry ; Ubiquitin ; Paired helical filaments
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The nature of Lewy bodies (LBs) in the brain stem and cerebral cortex in five cases of diffuse Lewy body disease and one case of Parkinson's disease with dementia were investigated immunocytochemically with various antibodies to cytoskeletal proteins, paired helical filaments (PHF) and ubiquitin. Antibodies to 200-kDa component of neurofilament, tau and PHF showed no significant reactions with most of LBs. Antibodies to high-molecular weight microtubule-associated proteins (HMWMAPs) moderately stained the periphery of a few of LBs. A monoclonal antibody to PHF (DF2) which recognizes ubiquitin, and polyclonal antibodies to ubiquitin immunostained virtually all of the typical and cortical LBs as intensely as Alzheimer's neurofibrillary tangles and senile plaque neurites: the periphery of LBs was darkly stained, whereas the central core of typical LBs and central zone of cortical LBs were less intensely stained or remained unstained. Immunoelectron microscopy of the LBs with DF2 revealed that immune reaction products were located on the filaments exclusively in the periphery of LBs, but not on those in the center. These findings suggest that both types of LBs are immunocytochemically indistinguishable despite some structural differences, and that peripherally located filaments in LBs are tagged with ubiquitin, an element required for the ATP-dependent proteolysis system in the cell. Antibodies to ubiquitin are the most useful marker of LBs ever known.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00687787
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  • 8
    Digitale Medien
    Digitale Medien
    Corticobasal degeneration: a disease with widespread appearance of abnormal tau and neurofibrillary tangles, and its relation to progressive supranuclear palsy (1994)
    Springer
    Acta neuropathologica 88 (1994), S. 113-121 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Key words: Corticobasal degeneration ; Progressive ; supranuclear palsy ; Neurofibrillary tangles ; Abnormal tau
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The neuropathological findings, including immunohistochemistry and electron microscopy, of two patients with clinical findings consistent with corticobasal degeneration (CBD) are reported. Both patients showed degeneration of the precentral cortex, the substantia nigra, the pallidum, and the thalamus. Many ballooned neurons were seen in the cerebral cortex, and argentophilic, skein-like inclusions suggesting neurofibrillary tangles (NFTs) were found in the brain stem and precentral cortex in patient 1. In contrast, patient 2 clearly showed NFTs in the brain stem and dentate nucleus which were indistinguishable from those seen in progressive supranuclear palsy (PSP), while only a few ballooned neurons were found in the cerebral cortex. Gallyas silver stain showed many argentophilic inclusions suggesting NFTs in the brain stem, subcortical nuclei, and cerebral cortex in both patients. Immunohistochemistry for tau showed tau-positive neurons in the cerebral cortex, brain stem, subcortical nuclei and spinal cord, and tau-positive glial cells were seen in the cerebral cortex, white matter and subcortical nuclei, and thread-like structures were seen in the cerebral cortex and white matter. Electron microscopy of the brain stem showed NFTs consisting of paired helical filaments in patient 1, and paired helical filaments and straight tubules in patient 2. Immunoelectron microscopy revealed parallel tau-positive filaments in the cerebral cortex in patent 1. From the two patients, the widespread appearance of abnormal tau and NFTs is one of the essential pathological features in CBD, and it also appears that CBD and PSP have some common underlying pathological processes. Patient 2 is closer to PSP than patient 1 and suggests CBD would link to PSP.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00294503
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  • 9
    Digitale Medien
    Digitale Medien
    Corticobasal degeneration: a disease with widespread appearance of abnormal tau and neurofibrillary tangles, and its relation to progressive supranuclear palsy (1994)
    Springer
    Acta neuropathologica 88 (1994), S. 113-121 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Corticobasal degeneration ; Progressive supranuclear palsy ; Neurofibrillary tangles ; Abnormal tau
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The neuropathological findings, including immunohistochemistry and electron microscopy, of two patients with clinical findings consistent with corticobasal degeneration (CBD) are reported. Both patients showed degeneration of the precentral cortex, the substantia nigra, the pallidum, and the thalamus. Many ballooned neurons were seen in the cerebral cortex, and argentophilic, skein-like inclusions suggesting neurofibrillary tangles (NFTs) were found in the brain stem and precentral cortex in patient 1. In contrast, patient 2 clearly showed NFTs in the brain stem and dentate nucleus which were indistinguishable from those seen in progressive supranuclear palsy (PSP), while only a few ballooned neurons were found in the cerebral cortex. Gallyas silver stain showed many argentophilic inclusions suggesting NFTs in the brain stem, subcortical nuclei, and cerebral cortex in both patients. Immunohistochemistry for tau showed tau-positive neurons in the cerebral cortex, brain stem, subcortical nuclei and spinal cord, and tau-positive glial cells were seen in the cerebral cortex, white matter and subcortical nuclei, and thread-like structures were seen in the cerebral cortex and white matter. Electron microscopy of the brain stem showed NFTs consisting of paired helical filaments in patient 1, and paired helical filaments and straight tubules in patient 2. Immunoelectron microscopy revealed parallel tau-positive filaments in the cerebral cortex in patent 1. From the two patients, the widespread appearance of abnormal tau and NFTs is one of the essential pathological features in CBD, and it also appears that CBD and PSP have some common underlying pathological processes. Patient 2 is closer to PSP than patient 1 and suggests CBD would link to PSP.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00294503
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