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Digitale Medien

Guillain-Barré syndrome associated with IgM anti-GM1 antibody followingCampylobacter jejuni enteritis (1994)

Sugita, K. ; Ishii, M. ; Takanashi, J. ; [weitere]

Springer

European journal of pediatrics 153 (1994), S. 181-183

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Details

ISSN: 1432-1076

Schlagwort(e): Guillain-Barré syndrome ; Anti-GM1 antibody ; Anti-GM2 antibody ; Campylobacter jejuni ; HLA-B35

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Abstract We report a 4-year-old girl diagnosed as having Guillain-Barré syndrome after infection by Penner serotype 19 ofCampylobacter jejuni. The patient had the HLA-B35 antigen. Neurological examination revealed distal-dominant weakness and intact sensation. Serial electrophysiological studies indicated that the predominant process was axonal degeneration involving motor nerves. An enzyme-linked immunosorbent assay revealed the presence of high titres of serum IgM antibodies to gangliosides GM1 and GM2. The IgM auto-antibody titres decreased concurrently with the clinical course of the illness and no switching from IgM to IgG secretion took place.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF01958981

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