ISSN:
1432-0533
Keywords:
β-β′-Iminodipropionitrile (IDPN)
;
Axonal Balloons
;
Protein Turnover Autoradiography
;
H3-Leucine
;
Spinal Motoneurons
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Autoradiography was performed in order to envisage the turnover of H3-leucin labeled protein in the perikarya of spinal motoneurons and in the axonal balloons formed after repeated administrations of IDPN (β-β′-iminodiproprionitrile) in rats. These results suggested that (1) there was no significant, if any,in situ protein synthesis within the axon balloons, (2) the protein turnover was not appreciably altered in the perikarya of the control and IDPN-intoxicated rats, and (3) the labeled protein collected in the axon balloons seemed to be transported from the perikarya to which they were linked with short axonal segments (30 μ in average length).
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00684521
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