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  • 1985-1989  (2)
  • 1980-1984  (2)
  • 1960-1964
  • 1986  (2)
  • 1982  (2)
Datenquelle
Materialart
Erscheinungszeitraum
  • 1985-1989  (2)
  • 1980-1984  (2)
  • 1960-1964
Jahr
Schlagwörter
  • 1
    Digitale Medien
    Digitale Medien
    Degeneration of retinal neuroblasts by chinoform-ferric chelate (1982)
    Springer
    Cellular and molecular life sciences 38 (1982), S. 120-122 
    Details
    ISSN: 1420-9071
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary The possible mechanism of neuropathic effect of chinoform was investigated using cultured retinal neuroblasts from chick embryos. Retinal neuroblasts completely degenerated by chinoform-ferric chelate within a day. This change, however, was not observed with free chinoform or ferric ion.a-Tocopherol had a potent protective effect on the toxicity of the chelate. From these results, it was concluded that the lipid peroxidation due to ferric ion chelated with chinoform incorporated into the membrane of nerve tissues is the most important step in induction of the neuropathy.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01944564
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Amygdalar inputs to ADH-secreting supraoptic neurones in rats (1982)
    Springer
    Experimental brain research 48 (1982), S. 420-428 
    Details
    ISSN: 1432-1106
    Schlagwort(e): ADH-neurone ; Amygdala ; Rat ; Supraoptic nucleus
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Effects of amygdala stimulation on the discharge activity of antidromically identified supraoptic neurosecretory neurones were studied in male rats anaesthetized with urethane. Stimulation of the medial and the basal amygdala produced excitation or inhibition of discharge activity both in phasically firing (“phasic”) and in continuously firing (”continuous”) neurones. More “phasic” neurones were excited than were inhibited after medial amygdala stimulation. On the other hand, fewer “continuous” neurones were excited by stimulation of the either amygdala area than were inhibited. This difference of responsiveness between “phasic” and “continuous” neurones is statistically significant. Synaptic inputs to supraoptic neurosecretory neurones after amygdala stimulation were also observed in rats with a lesion of the stria terminalis. Supraoptic nucleus stimulation activated antidromically 14 of the 336 amygdala neurones tested. Since “phasic” neurones have been identified as ADH-secreting neurones, it is concluded that ADH-secreting neurones in the rat supraoptic nucleus receive predominantly excitatory synaptic inputs from the medial amygdala and these amygdalar synaptic inputs are mediated by pathways which are at least in part monosynaptic and are not included in the stria terminalis.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00238618
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  • 3
    Digitale Medien
    Digitale Medien
    Synergistic activation of rat supraoptic neurosecretory neurons by noxious and hypovolemic stimuli (1986)
    Springer
    Experimental brain research 62 (1986), S. 572-578 
    Details
    ISSN: 1432-1106
    Schlagwort(e): Vasopressin cell ; Noxious input ; Hypovolemia ; Supraoptic nucleus ; Rat
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The effects of saphenous nerve stimulation on discharge activity of supraoptic neurosecretory (NS) cells were studied in anesthetized rats. Of 112 supraoptic neurosecretory cells, 62 exhibited a ‘phasic’ discharge pattern. The nerve stimulation transiently excited 46 of these 62 ‘phasic’ units, as well as 35 of the 50 remaining ‘non-phasic’ units. No appreciable blood pressure change was noted using PSTHs with 1-ms resolution. Though the nerve stimulation also evoked a flexor reflex of the ipsilateral hind limb, blockage of the hind limb movement with gallamine did not alter the amplitude of the supraoptic cell excitation. The threshold of the nerve stimulation was higher for the excitation than for the flexor reflex. Effects of hypovolemic and hyperosmotic stimuli on discharge activity of ‘phasic’ cells during saphenous nerve stimulation were studied to find a possible interaction between these stimuli. Hemorrhage potentiated the transient excitation evoked by the nerve stimulation in all of the 8 ‘phasic’ cells tested, while no such effect was seen after an injection of hypertonic sodium chloride solution in the 7 ‘phasic’ cells tested. These electrophysiological data suggest that hypovolemic and noxious stimuli potentiate VP secretion in a synergistic manner but that hyperosmotic and noxious stimuli do not.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00236036
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  • 4
    Digitale Medien
    Digitale Medien
    Epidemiological studies of hemorrhagic fever with renal syndrome (HFRS) related virus infection among urban rats in Hokkaido, Japan (1986)
    Springer
    Archives of virology 88 (1986), S. 231-240 
    Details
    ISSN: 1432-8798
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Seroepidemiological studies of hemorrhagic fever with renal syndrome (HFRS) virus infection were carried out among urban rats(Rattus norvegicus andRattus rattus) and small field rodents in Hokkaido, Japan. An urban rat colony that was seropositive to SR-11 strain of HFRS virus (laboratory rat origin) was demonstrated in February 1983 at a dumping ground area of Kami-iso Town near Hakodate port. An HFRS-related virus, named KI-262 strain, was isolated from the lung tissue of a seropositive rat using Vero-E6 cell culture. Antigenicity of the isolate was closely related to Hantaan 76–118 and SR-11 strains by the indirect immunofluorescent antibody (IFA) test. No seropositive rat was found among the 861 rats captured in 38 other regions. It is unclear whether or not the infected rats in the positive area were introduced from abroad, though the area is located near Hakodate International Port. Furthermore, higher positive rates of urban rats in the Kami-iso area were observed in the spring and winter than in the summer and fall. Significantly high proportion of positive cases was observed among adult rats (six months or older) than among younger animals. The seasonal and age distribution of postive cases suggested that the virus was not readily transmitted from one infected rat to another. One seropostive case of a small field mouse(Clethrionomys rufocanus bedfordiae) was detected around the Kami-iso area.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01310877
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