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  • 1980-1984  (2)
  • 1982  (2)
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  • 1980-1984  (2)
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  • 1
    Electronic Resource
    Electronic Resource
    A new glucose-6-phosphate dehydrogenase variant (G6PD Nagano) associated with congenital hemolytic anemia (1982)
    Springer
    Human genetics 〈Berlin〉 62 (1982), S. 368-370 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A new glucose-6-phosphate dehydrogenase (G6PD) variant associated with chronic nonspherocytic hemolytic anemia was reported. The patient, a 6-year-old Japanese male, was noticed to have hemolytic anemia soon after birth, and a diagnosis of G6PD deficiency was made at the age of 2. He had episodes of hemolytic crisis several times after upper respiratory infection. G6PD activity of the patient was 5.5% of normal. The enzymatic characteristics were examined when he was 5 years old, and his G6PD showed faster-than-normal electrophoretic mobility, low Km G6P, high Km NADP, low Ki NADPH, normal utilization of substrate analogues, heat instability, and a normal pH optimum curve. From these results, this was considered to be a new variant and was designated G6PD Nagano. Infection-induced hemolysis and chronic hemolytic anemia seem to be due to markedly impaired enzyme activity and thermal instability.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00304560
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Determination of pH in reversed micelles (1982)
    Springer
    Colloid & polymer science 260 (1982), S. 697-701 
    Details
    ISSN: 1435-1536
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The pH in the reversed micellar system of di(ethylhexyl) sodium sulfosuccinate (Aerosol OT, AOT) / phosphate buffer solutions/octane was determined by a P-NMR technique, and pHs in the reversed micelles containing buffer solutions other than the phosphate buffer solution were measured by the spectrophotometric method with the aid of Phenol Red. pHs in reversed micelles were found to be substantially determined by the buffer capacity of buffer solutions solubilized into the systems. By means of both the methods, pKa of Phenol Red in the systems was found to be 7.7, which is almost consistent with that in water. Analysis of Na-NMR spectra indicates that the mobility of the sodium ion of AOT is independent of the molar ratio of water to AOT when the ratio is above 7 and is restricted strongly by the interaction with the sulfonate group of AOT. The relationship between pH and the mobility of the sodium ion was discussed on the basis of the data of Na-NMR spectra.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01414656
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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