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  • 1980-1984  (9)
  • 1983  (4)
  • 1981  (5)
Material
Years
  • 1980-1984  (9)
Year
  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of organic chemistry 46 (1981), S. 1077-1082 
    ISSN: 1520-6904
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 41 (1983), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: Involvement of phosphate-activated glutaminase in Huntington's disease and agonal state was investigated in caudate nucleus and frontal cortex from postmortem brains. In Huntington's disease the activities of phosphate-activated glutaminase, glutamic acid decarboxylase, succinic dehydrogenase, choline acetyl-transferase, and acetylcholinesterase were significantly reduced in the caudate nucleus, but not in the frontal cortex. The activity of phosphate-activated glutaminase, and to a lesser extent of glutamic acid decarboxylase, was reduced in cases of terminal illness, as compared with cases of sudden death. Succinic dehydrogenase and choline acetyltransferase were reduced only in the few cases of prolonged and severe terminal illness. Enzyme activities of the caudate nucleus were more affected by agonal state than were those of frontal cortex. Results indicate that phosphate-activated glutaminase could be a useful marker of neuronal damage due to agonal state, and that phosphate-activated glutaminase and succinic dehydrogenase are reduced in Huntington's disease.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 37 (1981), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: [14C]Acetyl-CoA was found to react spontaneously with dithiothreitol to give a relatively apolar product which was readily extractable into a butanol-toluene scintillant. This technique was used in a rapid, reproducible assay for rat brain ATP:citrate lyase using [1,5-14C]citrate as substrate. The tissue extract, a 14,000 g supernatant, exhibited a lyase activity of approximately 7 nmol acetyl-CoA produced/min per mg supernatant protein, and was inhibited ≥79% by α-ketoglutaric acid (10 mm), Cu2+ (1 mm)and Zn2+(1 mm). [14C]Oxaloacetate, [14C]malate and endogenous citrate synthase were found not to interfere significantly with lyase estimations, but NADH was required in the reaction mixture to inhibit acetyl-CoA hydrolase activity.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Nuclear and Particle Science 33 (1983), S. 323-382 
    ISSN: 0163-8998
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 5
    facet.materialart.
    Unknown
    Oxford : Periodicals Archive Online (PAO)
    Medium aevum. 50 (1981) 301 
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  • 6
    ISSN: 1439-0973
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Verteilung von Mannose-resistenten (MRHA) und Mannose-empfindlichen (MSHA) Fimbrien-Hämagglutininen wurde bei 482Escherichia coli-Stämmen untersucht; die Isolate stammten von 390 erwachsenen Frauen und 45 Schwangeren mit Harnwegsinfektionen verschiedener Art und von 47 gesunden Kontrollpersonen. Der Anteil von MRHA-Stämmen war bei Patienten mit symptomatischer Harnwegsinfektion (75%) signifikant höher als bei Frauen mit nicht signifikanter Bakteriurie (30%; p〈0,001). Schwangeren mit asymptomatischer Harnwegsinfektion (34%; p〈0,0001) und gesunden Kontrollpersonen (0%). Der Anteil von MSHA-Stämmen war bei Patienten mit symptomatischer Harnwegsinfektion signifikant geringer (22%) als bei Frauen mit nichtsignifikanter Bakteriurie (46%; p〈0,001) und Schwangeren mit symptomatischer Harnwegsinfektion (52%; p〈0,01). Nur 17% der Stämme von gesunden Kontrollpersonen wiesen MSHA-Aktivität auf. Bei Schwangeren mit Harnwegsinfektion war eine signifikante Assoziation zwischen der Infektion mit MRHA-Stämmen vonE. coli und einer früher durchgemachten Harnwegsinfektion nachzuweisen — unabhängig davon, ob klinische Symptome bestanden oder nicht. Bei Schwangeren mit anamnestisch erfaßter Harnwegsinfektion besteht somit eine siebenmal höhere Wahrscheinlichkeit, daß das Pathogen ein MRHA-tragender Keim ist als bei Frauen ohne entsprechende Vorgeschichte. Zwischen MRHA-Keimen und symptomatischer Infektion bestand ebenfalls eine signifikante Assoziation. Patienten mit klinisch manifester Harnwegsinfektion weisen ein sechsmal höheres Risiko für eine Infektion mit einem MRHA-Stamm auf als Patienten mit klinisch stummer Infektion.
    Notes: Summary The distribution of mannose-resistant (MRHA) and mannose-sensitive (MSHA) fimbrial haemagglutinins was examined in 482 strains ofEscherichia coli isolated from 390 adult women and 45 pregnant mothers with a variety of urinary tract infections (UTI), and from 47 healthy controls. The proportion of MRHA strains was significantly higher in patients with symptomatic UTI (75%) than in women with non-significant bacteriuria (30%, p〈0.001), pregnant women with asymptomatic UTI (34%, p〈0.001) and healthy controls (0%). The proportion of MSHA strains was significantly lower in patients with symptomatic UTI (22%) than in women with non-significant bacteriuria (46%, p〈0.001) and pregnant women with asymptomatic UTI (52%, p〈0.01). Only 17% of the strains from healthy controls had MSHA activity. In pregnant women with UTI, whether this was symptomatic or asymptomatic, there was a significant association between infection with MRHA strains ofE. coli and a past history of UTI. Thus, in a pregnant woman with an infection and a past history of UTI there is a seven-fold greater chance that this infection is due to an MRHA-bearing organism than in pregnant women without such a history. There was also a significant association between MRHA organisms and symptomatic infection. The risk of symptomatic patients having an infection with an MRHA strain is six times greater than that for a patient with a covert infection.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Veterinary research communications 5 (1981), S. 63-66 
    ISSN: 1573-7446
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Faecal samples were collected from newly impounded stray dogs and from dogs presented to a clinic by their owners. The dogs were categorised as strays or pets and their faeces as formed or unformed. The faeces were examined bacteriologically. Campylobacters were significantly (P〈0.01) more frequently isolated from the faeces of the stray dogs but there was no significant difference between the frequency of isolation of the organism from formed or unformed faeces. The significance of this finding in relation to public health and animal health is noted.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Veterinary research communications 6 (1983), S. 133-138 
    ISSN: 1573-7446
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Faecal samples were collected from impounded stray dogs, classified as under or over six months of age, on their arrival in kennels and again 5–7 days later. The faeces were examined for the presence of campylobacters, salmonella andGiardia lamblia. No significant difference was found in the rate of isolation of these organisms between the two age groups. There was, however, a significant increase in the rate of isolation at days 5–7 compared with day 1. It is suggested that while dogs may acquire campylobacter infection in kennels, excretion of the organism may be intermittent and may be precipitated by stress. A low incidence of salmonellae andGiardia lamblia excretion was detected.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 15 (1981), S. 867-878 
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Mechanisms of corrosion at the areas of contact between screw heads and plate holes were investigated using electrochemical potential recording techniques. Static crevice corrosion was studied with plates and screws in isotonic and hypertonic saline solutions (0.9 to 7.2% NaCl). Fretting corrosion was studied in vitro with plates screwed to tubular bone analogs which were subjected to cyclic axial loads, and was studied in vivo with plates screwed on the tibia of sheep. Static tests showed that crevice corrosion does not occur in isotonic saline for periods up to one year, but can occur in hypertonic saline solutions. Dynamic loading tests demonstrated immediate potential changes which were related to the magnitude of the applied load, indicating fretting corrosion due to motion between screw head and plate, both in vitro and in vivo. A mechanism for screw-plate relative motion is proposed. It is hypothesized that corrosion seen in clinically retrieved implants due to fretting corrosion which predisposes the contact area to crevice corrosion attack.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
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