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  • Electronic Resource  (16)
  • 1985-1989  (12)
  • 1970-1974  (4)
  • 1955-1959
  • 1985  (12)
  • 1971  (4)
Material
  • Electronic Resource  (16)
Years
  • 1985-1989  (12)
  • 1970-1974  (4)
  • 1955-1959
Year
  • 1
    Electronic Resource
    Electronic Resource
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Immunology 3 (1985), S. 87-108 
    ISSN: 0732-0582
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 56 (1985), S. 359-363 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: Design considerations and experimental results are described for a charge exchange neutral particle mass and energy analyzer for JT-60, which analyzes H, D, and He simultaneously up to a maximum energy of 110 keV. The analyzer has separately a 180° deflection magnet for momentum analysis and an electrostatic deflector for mass analysis. The way to control the effect of the electric fringe fields in order to expand the detectable energy range is studied by numerical simulation. The deflector is then designed, made of two triangular plates and three additional electrodes for the control of the fringe fields. The effect of the deflector is demonstrated experimentally. Energy and mass resolution and the relation between the incident ion energy and the magnetic field strength are measured. The results of the calibration experiments agree with the designed value.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 89 (1985), S. 5098-5101 
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cutaneous pathology 12 (1985), S. 0 
    ISSN: 1600-0560
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Serum amyloid P component (SAP) is present not only in all types of cutaneous amyloidosis, but also in the normal dermal clastic fibers as well as abnormal elastic-fibers, such as clastotic degeneration of clastic fibers in actinic keratosis. It was previously postulated that the colloid substance in colloid milium is a final degeneration stage of actinic clastosis. In a lesion of colloid milium SAP was intensely positive with an indirect iinmuiiofluorescence method using rabbit antiserum to human SAP. Electron microscopy of the colloid lesion revealed components of normal elastic fibers as well as those of actinic elastoid as seen in actinic clastosis. It is concluded that the colloid substance derives, at least in major part, from elastic fibers through actinic degeneration.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 113 (1985), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The presence of a tissue plasminogen activator inhibitor in the epidermis was investigated. A partially purified tissue plasminogen activator from a Bowes melanoma cell line medium was used as a tissue plasminogen activator. Extracts of epidermis dissolved in a 10 mM phosphate buffer, pH 7.0, were found to contain a tissue plasminogen activator inhibitor. The same extracts also contained a urokinase inhibitor. It is not clear whether these inhibitors are the same. This study is the first to show the existence of a tissue plasminogen activator inhibitor in the epidermis.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cutaneous pathology 12 (1985), S. 0 
    ISSN: 1600-0560
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A black baby, born al full term of a normal healthy mother, showed multiple erosions and ulcers. No history of skin diseases was known in the family. A skin biopsy taken shortly after birth from an arm lesion showed subepidermal edema and cavity formation. Electron microscopy showed clumping of microfibrils and anchoring fibril-like fibers at the dermo-epidermal junction. In more severely affected areas, absence of anchoring fibrils and collagenolysis were found and the diagnosis of dystrophic epidermolysis bullosa was made. Two weeks later, the lesions healed without leaving scars and a second biopsy from the chest area revealed typical histopathology of epidermolytic hyperkeratosis.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cutaneous pathology 12 (1985), S. 0 
    ISSN: 1600-0560
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Two starfishes, “togemomijigai” Astropecten polyacanthus and “momijigai” A. scoparius were collected from the Seto Inland Sea in October 1983 through November 1984, and assayed for toxicity by the standard method for tetrodotoxin (TTX). Most of the 54 A. polyacanthus specimens assayed were toxic, with the highest toxicity score being 520 mouse units (MU) g-1. All seven A. scoparius were toxic, with the highest score being 46 MU g-1. The toxin from A. polyacanthus was purified by a method which consisted mainly of activated charcoal treatment, and chromatography on CM-Sephadex C-25 and Bio-Rex 70 columns. The purified starfish toxin showed a specific toxicity of 4 700 MU mg-1, a value which was almost comparable to that of authentic TTX. From the thin-layer chromatographic and electrophoretic behavior, along with 1H-NMR spectrum, A. polyacanthus toxin was identified as TTX.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Archives of dermatological research 240 (1971), S. 1-22 
    ISSN: 1432-069X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Nagelzellen, die von den ventralen, apikalen und dorsalen Anteilen der proximalen Matrix gebildet wurden, rückten in axial-distaler Richtung vorwärts, bis sie amproximalen Verhornungspunkte zusammentrafen. Von diesem Punkte an wurden der proximalen Nagelplatte ununterbrochen Zellen von der ventralen und dorsalen Matrix und vom Nagelbett zugefügt. Bald hörte die dorsale Matrix auf, Nagelzellen zu entwickeln und wurde weiter distal in den hinteren Nagelfalz umgewandelt. Mit der differentialen Phasenkontrast-Apparatur von Zeiss-Nomarski konnte man die Teilung der proximalen Nagelplatte in eine ventrale und dorsale Hälfte erkennen. Nächst der Lunula entwickelte das Nagelbett noch eine weitere deutliche Schicht unter der proximalen ventralen Schicht. Elektronmikroskopisch zeigten alle Nagelzellen, ohne Rücksicht auf ihren Ursprung, Verhornung durch Anhäufung von Fibrillen ohne Bildung von Keratohyalinkörnern. Membrane-coating granules (MCG) entstanden in reichlicher Menge. Sie wurden abgestoßen und bildeten die intercellulßre Kittsubstanz. Das abgestoßene Material erweiterte einige der engen Membranspalten, während es gewöhnliche, klaffende (nicht-spezifische) Zellgrenzen verengte und dadurch 150–180 Å weite intercelluläre Zwischenräume bildete, nämlich dieengen Zellverkittungen. Die engen Zellverkittungen stellten den häufigsten Typ der intercellulären Anlagerung dar, wodurch die verhornten Nagelzellen zusammengehalten wurden. Die dicke Zellhülle der verhornten Zellen, nämlich dasGrenzband, wurde durch Niederschlag von dichtem Material an der protoplasmatischen Seite der Zellmembran gebildet und nicht durch die membrane-coating granules.
    Notes: Summary The nail cells produced in the ventral, apical and dorsal portions of the proximal matrix moved in axiodistal direction to meat together at theproximal point of keratinization. The proximal nail plate from this point on was added continuously by the cells from ventral matrix and nail bed. Dorsal matrix soon ceased to produce nail cells and further distally transformed into the posterior nail fold. With Zeiss-Nomarski differential interference contrast equipment, the proximal nail plate could be divided into the ventral and dorsal halves. Near the lunula the nail bed produced one more distinct layer beneath the proximal ventral layer. Electron miscroscopically all nail cells regardless of their origins were seen keratinizing by accretion of tonofibrils without formation of keratohyaline granules. Membrane-coating granules (MGG's) were produced in abundance. They were discharged and provided the intercellular cement. The discharged material widened some of the gap junctions while it tightened nonspeccific junctions to produce 150–180 Å intercellular spaces, i.e. thenarrow junctions. The narrow junctions were the most common type of intercellular junction connecting the keratinized nail cells. The thick cellular envelope of the keratinized cells, i.e. themarginal band, was formed by a precipitation of dense material on the cytoplasmic side of the plasma membranes and not by discharged MCG's.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Archives of dermatological research 240 (1971), S. 349-364 
    ISSN: 1432-069X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Kleine protoplasmatische Körnchen, welche in verschiedenen verhornenden Epithelien gefunden worden sind und als der Zellmembran aufliegende Körnchen oder Keratinosome bezeichnet wurden, konnten durch Phospholipase C gespalten werden. Körnchen, die in die intercellulären Zwischenräume abgestoßen waren, waren gleichfalls durch Phospholipase C spaltbar. Da angenommen wird, daß Phosphatide einen Teil der intercellularen Kittsubstanz bilden, nicht nur in der Haut, sondern auch in anderen eng zusammengefügten Epithelien, wird die Bezeichnung „Kittkörnchen“ oder „Kittkörper“ für diese Körnchen vorgeschlagen.
    Notes: Summary Small cytoplasmic granules, which have been found in various keratinizing epithelia and called the membrane-coating granules or keratinosomes, were found to be amenable to phospholipase C digestion. Granules discharged into the intercellular spaces could also be digested with phospholipase C. Since it is believed that phospholipids are part of the intercellular cement not only in the skin but in other tightly junctioned epithelia, the name “cement granule” or “cementsome” was proposed for these granules.
    Type of Medium: Electronic Resource
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