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  • 2000-2004  (4)
  • 1985-1989
  • 1910-1914
  • 2003  (4)
  • 1
    Electronic Resource
    Electronic Resource
    Congenital adrenal hyperplasia and acne in male patients (2003)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 148 (2003), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary Seborrhoea is one pathogenic factor for acne. Androgens induce sebum production, and excess androgen may provoke or aggravate acne. In women an androgen disorder is frequently suspected when acne is accompanied by hirsutism or menstrual irregularities. In men acne may be the only symptom of androgen excess. We report three male acne patients in whom hormonal screening revealed irregularities of androgen metabolism suggestive of late-onset congenital adrenal hyperplasia and who benefitted from low-dose glucocorticoids. Disorders of androgen metabolism may influence acne not only in women, but also in men, and these patients may benefit from low-dose glucocorticoid therapy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2133.2003.05369.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Serum antibody reactivity against recombinant PrtC of Porphyromonas gingivalis following periodontal therapy (2003)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 38 (2003), S. 0 
    Details
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objectives:  In 34 patients with chronic periodontitis, the presence of IgA, IgG, and IgG subclass serum antibodies against recombinant PrtC (rPrtC) of Porphyromonas gingivalis was assessed by immunoblot analysis 24 months after therapy.Methods:  rPrtC was produced from P. gingivalis ATTC 33277 using the plasmid pGEX-2T. In addition, intraoral colonization with P. gingivalis was detected by PCR in subgingival plaque and swab samples from buccal mucosae, tonsils and tongue at baseline, 10 d, and 3, 6, 9, 12, 18, and 24 months.Results:  All patients were found to harbor P. gingivalis in the oral cavity at least once during the observation period. The identified antibody responses against the rPrtC of P. gingivalis were IgA (97%, i.e. 33/34 patients) and IgG (100%, i.e. 34/34), with an IgG subclass distribution of IgG2 (65%, i.e. 22/34 patients) 〉 IgG3 (47%, i.e. 16/34) 〉 IgG1 (38%, i.e. 13/34) 〉 IgG4 (29%, i.e. 10/34). Anti-rPrtC IgA and IgG antibody reactivity was found in all but one patients (anti-rPrtC IgA negative), who tested negative for P. gingivalis at all of the assessed intraoral sites for at least 6 months before sera collection. There was no association between IgG subclass reactivity against the rPrtC of P. gingivalis and progression of periodontal attachment loss.Conclusion:  The results indicated that anti-rPrtC IgA and IgG antibodies may serve as an indicator for past or present intraoral colonization with P. gingivalis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-0765.2003.01405.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Improved upper and lower energy bounds for antiferromagnetic Heisenberg spin systems (2003)
    Springer
    The European physical journal 33 (2003), S. 285-292 
    Details
    ISSN: 1434-6036
    Keywords: PACS. 75.10.Jm Quantized spin models – 75.50.Xx Molecular magnets – 75.50.Ee Antiferromagnetics – 75.40.Mg Numerical simulation studies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract: Large spin systems as given by magnetic macromolecules or two-dimensional spin arrays rule out an exact diagonalization of the Hamiltonian. Nevertheless, it is possible to derive upper and lower bounds of the minimal energies, i.e. the smallest energies for a given total spin S. The energy bounds are derived under additional assumptions on the topology of the coupling between the spins. The upper bound follows from “n-cyclicity", which roughly means that the graph of interactions can be wrapped round a ring with n vertices. The lower bound improves earlier results and follows from “n-homogeneity", i.e. from the assumption that the set of spins can be decomposed into n subsets where the interactions inside and between spins of different subsets fulfill certain homogeneity conditions. Many Heisenberg spin systems comply with both concepts such that both bounds are available. By investigating small systems which can be numerically diagonalized we find that the upper bounds are considerably closer to the true minimal energies than the lower ones.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1140/epjb/e2003-00168-5
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Power-law decay of collisionally excited amino acids and quenching by radiative cooling (2003)
    Springer
    The European physical journal 25 (2003), S. 139-148 
    Details
    ISSN: 1434-6079
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract. We have investigated the time dependence of the fragmentation of protonated amino acids stored at 22 keV in the electrostatic ring ELISA. The ions were produced in an electrospray source and after bunching in a quadrupole trap they were excited by collisions in a Ne gas. As in earlier studies of metal clusters and fullerenes produced in “hot” ion sources we find that the dissociation of metastable molecules follows approximately a 1/t decay law until a time $\tau$ after which the yield falls off much more rapidly. We interpret this reduction as a result of radiative cooling with a characteristic cooling time, $\tau_c \simeq G\tau$ , where G is the magnitude of the exponent in an Arrhenius expression for the rate of the dominant fragmentation process. The values of $\tau$ obtained from fits to the data are in the range 9-17 ms corresponding to cooling times of a few hundred milliseconds, in good accord with the expected rate of cooling by emission from IR-active vibrations. The power-law behaviour for $t 〈 \tau$ varies somewhat between the different amino acids, with powers between -0.9 and -1.1. We argue that this may be due to a competition between fragmentation channels with different Arrhenius parameters.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1140/epjd/e2003-00093-9
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    Paper (German National Licenses)
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