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  • 2000-2004  (3)
  • 2003  (3)
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  • 2000-2004  (3)
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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Journal of fish biology 63 (2003), S. 0 
    ISSN: 1095-8649
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: The opening of a deep artificial and second entrance channel into the large Peel-Harvey Estuary in south-western Australia in 1994 provided a unique opportunity to determine the characteristics of the ichthyofauna of a microtidal estuary, in which tidal water movement and the rate of recovery of salinities in spring have both increased markedly. Fishes in the original entrance channel and both halves of the two large basins (Peel Inlet and Harvey Estuary), which constitute most of the total area of the estuary, were sampled using a 21·5 m long seine with a fine (3 mm) mesh bunt. The 72 337 fishes that were caught throughout the estuary and represented 43 species, comprised mainly marine species, both in terms of number of species (65·1%) and number of individuals (70·6%). The number of species and density of fishes in each region, and particularly in the basins, showed a pronounced tendency to decline from a maxima in summer to a minima in winter and then to rise in spring. Although the species composition of the fish fauna in the natural entrance channel differed significantly from that in each of the four basin regions, those within the basins were significantly different only in the cases of the southern Harvey Estuary versus both regions of the Peel Inlet. Species composition in the natural entrance channel and four basin regions each underwent conspicuous cyclical changes during the year, which reflected out-of-phase changes in the densities of certain species. Although this cyclical pattern was due mainly to changes in the densities of marine species, it was augmented by those of estuarine residents. The cyclicity, which was not evident prior to the opening of the artificial Dawesville Channel, and thus when tidal water movement within the estuary was far less pronounced, parallels the situation recorded for macrotidal northern hemisphere estuaries.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Haemophilia 9 (2003), S. 0 
    ISSN: 1365-2516
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary.  Von Willebrand disease (vWD) is the most common bleeding disorder, and usually presents with either easy bruising or mucus membrane bleeding. Many patients are also diagnosed as a result of abnormal pre-operative laboratory tests. In this report, we describe two patients presenting with painless, persistent urethral bleeding as their initial manifestation of vWD. The first patient began bleeding after a Foley catheter was placed during a hospital admission for status epilepticus. A urologic examination demonstrated a wound in the posterior urethra. Despite repeated attempts at controlling the bleeding with cautery, the bleeding persisted. The second patient presented with spontaneous urethral bleeding and a normal urologic examination. Due to persistent bleeding, both patients underwent a coagulation evaluation that demonstrated the presence of type 1 vWD. The first patient had resolution of his bleeding following 5 weeks of Alphanate, a von Willebrand factor containing factor VIII concentrate, and aminocaproic acid. The second patient initially responded to desmopressin, but subsequently required Humate-P to achieve complete resolution. These cases illustrate the importance of an evaluation for bleeding disorders in patients with persistent bleeding from any site.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background : Colorectal cancer screening by guaiac faecal occult blood test has been shown to reduce the incidence and mortality of colorectal cancer in Western populations. The optimal faecal occult blood test, whether guaiac or immunochemical, for colorectal cancer screening in the Chinese population remains to be defined.Aim : To compare the performance characteristics of a sensitive guaiac-based faecal occult blood test (Hemoccult SENSA) and an immunochemical faecal occult blood test (FlexSure OBT) in a Chinese population referred for colonoscopy.Methods : One hundred and thirty-five consecutive patients who were referred for colonoscopy and who met the study inclusion criteria took samples for the two faecal occult blood tests simultaneously from three successive stool specimens, with no dietary restrictions. All tests were developed and interpreted by a single experienced technician who was blind to the clinical diagnosis. The sensitivity, specificity and positive predictive value for the detection of colorectal adenomas and cancers were estimated for the two tests.Results : The sensitivity, specificity and positive predictive value for the detection of significant colorectal neoplasia (adenomas ≥ 1.0 cm and cancers) were 91%, 70% and 18% for Hemoccult SENSA and 82%, 94% and 47% for FlexSure OBT. The specificity and positive predictive value were significantly higher for FlexSure OBT than for Hemoccult SENSA (P 〈 0.001 and P = 0.016, respectively). Combining the positive results from both faecal occult blood tests did not improve the accuracy.Conclusion : The positive predictive value of the immunochemical faecal occult blood test for the detection of significant colorectal neoplasia was 29% better than that of the sensitive guaiac-based test. This may relate to the Chinese diet and requires further study. The poor specificity of the sensitive guaiac-based test, without dietary restriction, makes it less useful for colorectal cancer screening in a Chinese population.
    Type of Medium: Electronic Resource
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