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  • 1
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Physics of Fluids 6 (1994), S. 435-437 
    ISSN: 1089-7666
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A presentation is given of the results of two-dimensional lattice gas cellular automata (LGA) simulations for calculating the permeability for flow through periodic arrays of cylinders, where the cylinders have either a rhomboid or cruciform cross section. For the case of rhombi, the results are related via a semiempirical shape factor to analytical solutions for flow through arrays of circular cylinders. Finite size effects are studied by comparing simulation results with theory. This calibration of the LGA model then validates its use for the study of flow around cruciforms, for which there is no analytical solution. This has an important application in the mathematical modeling of flow through arrays of dendrites in the mushy region during the solidification of alloy steel.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1520-6033
    Source: ACS Legacy Archives
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Geophysical journal international 105 (1991), S. 0 
    ISSN: 1365-246X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: A study is made of the dependence of the effective permeability of sand-shale reservoirs on the geometry of the shale inclusions. Numerical simulations are described in which factors such as the orientation and the degree of anisotropy of the shales, their volume fraction and the permeability contrast ratio between the shale and the sandstone were varied. Two different reservoir models were used in the simulations: one in which the shales were in the form of random, overlapping spheroidal inclusions, and one in which the shales were generated by a geostatistical technique. The computed effective permeability data are compared with a variety of analytical models in an attempt to discover ‘rules of thumb’for the estimation of the effective permeability of sand-shale reservoirs for use in a range of practical situations. The main technical way in which this study advances on previous work is in its use of a computationally efficient, random walk algorithm for calculating the effective permeability, which has enabled larger volumes to be simulated and, hence, a thorough investigation of finite-size effects to be made. Another advantage of the work reported here is the general nature of the sand-shale geometries used in the numerical simulations and the extensive comparisons with analytical models.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Alimentary pharmacology & therapeutics 21 (2005), S. 0 
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background : While wintertime vitamin D deficiency has been well-documented in Crohn's disease patients, less is known about vitamin D status during summertime and whether a seasonal variation exists in bone turnover.Aims : To compare vitamin D status and bone turnover markers in Crohn's disease patients with age- and sex-matched controls during late-summer and late-winter.Subjects : Crohn's disease patients (n = 44; mean age 36.9 years, currently in remission) and matched controls (n = 44) were recruited from Cork University Hospital and Cork City area, respectively.Methods : Bloods were analysed for 25-hydroxyvitamin D, parathyroid hormone, bone-specific alkaline phosphatase, osteocalcin and urine analysed for N-telopeptides of type 1 collagen.Results : Serum 25-hydroxyvitamin D concentrations were significantly (P 〈 0.003) lower in Crohn's disease patients than in control subjects during both seasons. In Crohn's disease patients, serum 25-hydroxyvitamin D concentrations were lower (P 〈 0.0001) whereas serum parathyroid hormone, osteocalcin and bone-specific alkaline phosphatase and urinary N-telopeptides of type 1 collagen levels were higher (P 〈 0.001) during late-winter than late-summer.Conclusion : There were notable seasonal variations in vitamin D status and bone turnover markers in Crohn's disease patients. The impact of winter decline in vitamin D status and increase in bone turnover on long-term risk of osteopenia/osteoporosis in Crohn's disease patients is unclear.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: The atp operon of Escherichia coli directs synthesis rates of protein subunits that are well matched to the requirements of assembly of the membrane-bound H+-ATPase (α3β3γ1δ1σ1a1b2c10–15). Segmental differences in mRNA stability are shown to contribute to the differential control of atp gene expression. The first two genes of the operon, atpl and atpB, are rapidly inactivated at the mRNA level. The remaining seven genes are more stable. It has previously been established that the translational efficiencies of the atp genes vary greatly. Thus differential expression from this operon is achieved via post-transcriptional control exerted at two levels. Neither enhancement of translational efficiency nor insertion of repetitive extragenic palindromic (REP) sequences into the atplB intercistronic region stabilized atpl. We discuss the implications of these results in terms of the pathway of mRNA degradation and of the role of mRNA stability in the control of gene expression.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Molecular microbiology 4 (1990), S. 0 
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Post-transcriptional control mechanisms assume special significance in polycistronic operons. Differential gene expression in the atp operon of Escherichia coli is primarily attributable to translational control and, to a lesser extent, to control of mRNA stability. At the same time, the polycistronic environment influences, to varying degrees, the relative importance of the different types of post-transcriptional control. The present article briefly reviews more recent results obtained through studies of the atp operon. Investigations of the pathway and kinetics of mRNA decay have yielded new information about the role of degradative mechanisms in the overall scheme of control. Moreover, translational coupling has been shown to feature as a major form of interaction between the atp genes. The relevance of these and other data is discussed in the wider context of the post-transcriptional control mechanisms generally available to E. coli.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the American Water Resources Association 8 (1972), S. 0 
    ISSN: 1752-1688
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Architecture, Civil Engineering, Surveying , Geography
    Notes: The properties of an instantaneous unit hydrograph model consisting of two cascades of linear reservoirs in parallel were explored with the aid of an analog computer. By proper choice of the model parameters it is possible to produce two-peaked instantaneous unit hydrographs. The relative magnitudes and locations of the two peaks can be varied by changing the values of the parameters. An example of the use of the analog computer to select the parameters of the model giving the best fit to an observed runoff hydrograph is also included. The analog computer used in the study was the ASTRAC II developed at the University of Arizona.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: A series of afp::lacZ fusions has been constructed for use in a study of translational coupling in the central region of the Escherichia coli atp operon. Five genes, atpE, atpF, atpH, atp A and atpG, were shown to be translationally coupled to various degrees of tightness. A new lac promoter vector, compatible with the afp::lacZ fusion vectors, was used to express individual atp genes in the same hosts as the fusion genes. The H+-ATPase subunits thus synthesized exercised no significant trans-regulation on the expression of the atp::lacZ fusions, indicating that the coupling is primarily cis. The mechanism of this coupling was investigated using in vitro mutagenesis. At least in the case of the pair atpHA, coupling seems to involve facilitated binding of fresh ribosomes to the atpA translational initiation regions.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Over a 2-year program of monthly cruises covering the entire Chesapeake Bay (USA), the phytoplankters which passed 35 μm mesh were responsible for 89.6% of the phytoplankton productivity. On a single summer cruise, the 〈35 μm phytoplankton fraction was responsible for 93.4% of the chlorophyll a and 100% of the primary productivity. The 〈10 μm fraction was responsible for 81.3% of the chlorophyll a and 94% of the productivity. The difference in biomass in the 〈35 μm and the 〈10 μm fractions was significant (P=0.025), but no significant difference in the productivity could be demonstrated. Laboratory experiments demonstrated that recently assimilated carbon can be lost with gravity screening. Considering both this and the effect of herbivorous zooplankters enclosed in productivity incubations, a prescreening rather than postscreening technique is recommended for studying nanoplankton productivity.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 341 (1992), S. 275-287 
    ISSN: 1434-601X
    Keywords: 25.30.Fj ; 13.60.Hb
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Using the Ward-Takahashi identity, on-shell condition, bound Dirac equation and off-shell expansion, a reduced version of half off-shell virtual photon nucleon vertex has been suggested. The vertex are decomposed into several different order terms: the on-shell terms, first and second off-shell terms. The off-shell behaviour of the form factors is discussed in the one meson loop model. Using the reduced vertex and parametrized off-shell form factors the quasielastic response functions are calculated for several nuclei at ¦q¦–kf and for56Fe at large ¦q¦ up to 1.14 GeV/c and at −q2=0.9 (GeV/c)2. The Coulomb sums are evaluated and a comparison of the theoretical prediction with data is given. The off-shell electron nucleon cross section is calculated and compared with the “cc1” off-shell extrapolation.
    Type of Medium: Electronic Resource
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