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  • 2005-2009  (8)
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  • 1
    ISSN: 1662-0356
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Natural Sciences in General , Technology
    Notes: The current-carrying properties beyond a critical current determined by a voltage criterionfor Ag-sheathed Bi2Sr2CaCu2O8 (Ag/Bi2212) superconductors are examined at 10 K and 20 K inmagnetic fields. We prepared the in-field heat-treated Ag/Bi2212 wires, in order to obtain themagnetic field alignment microstructure for Ag/Bi2212. The electric field and current density (E-J)properties were evaluated for Ag/Bi2212 wires with and without the in-field heat-treatment. Wefound that the E-J properties for the in-field heat-treated Ag/Bi2212 wires differ from those for theout-of-field heat-treated ones, and are analogous to the E-J dependence for Bi-system hightemperature superconductors with the sintered-like grain morphology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 330-332 (Feb. 2007), p. 597-600 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The aim of this study is to evaluate the effects of coating implants with hydroxyapatite(HA) by an ion beam-assisted deposition (IBAD) method and to compare them with implantsprepared with machined and anodized surfaces. Twenty-four implants in this study were divided intothree groups; machined, anodized, anodized plus IBAD surface implants. Implant stability andosseointegration were assessed by resonance frequency analysis (RFA) and histologic analysis. Wecan conclude that implants coated by HA by IBAD demonstrate characteristics of contactosteogenesis, but the research design does not permit conclusions regarding long-term treatmentoutcome with implants. Further studies are needed
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Advanced materials research Vol. 26-28 (Oct. 2007), p. 213-216 
    ISSN: 1662-8985
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The crystallographic orientation distribution, and its change as a function of creepdeformation in Ni-based single crystal superalloys have been investigated by X-ray diffractometry.The distribution of the crystallographic orientation has significantly broadened by creepdeformations. Directional broadening of the distribution agrees with creep dislocations having theburgers vector of 1/2〈101〉. High temperature creep strain of superalloys can be estimated by anon-destractive test where the width of rocking curve of a diffraction peak is measured
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 558-559 (Oct. 2007), p. 1309-1312 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: It is well known that the ultra grain refinement can be achieved by sever cold rolling, followedby reversion treatment in metastable austenitic stainless steel plate. In this study, the cold rolling wasreplaced by cold drawing. This procedure was applied to a metastable austenitic steel (Fe-16Cr-10Nialloy) thin wire, and then the microstructure development during cold drawing and annealing wasinvestigated. The austenite phase transformed to martensite during the drawing. Vickers hardness of thewire markedly increased with increasing the drawing strain. When the drawing strain reached about 4.5,the wire exhibited martensite single structure and had high hardness of Hv4.4GPa. Annealing of theheavily drawn wire at around 900K for 0.6ks leads to the formation of reversed austenite with thediffusional reversion mechanism. As a result, ultra fine-grained austenitic single structure with the grainsize of about 0.6μm was obtained. It was also found that the wire has an excellent combination of astrength and ductility
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1468-2494
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Hair treatment chemicals induce sudden and severe hair damage. In this study, we examined cuticles from untreated, permed, and bleached hair that were mechanically discriminated by shaking in water. Both perming and bleaching treatments are prone to easily delaminate cuticles. Confocal microscopy revealed that the cuticles of permed hair were delaminated with larger pieces than untreated ones. On the other hand, the cuticles of bleached hair tend to fragment into small peptides. At the minimum concentration of thioglycolate required to elute S100A3 protein from the endocuticle into the reductive permanent waving lotion, enlarged delaminated cuticle fragments were observed. Although S100A3 is retained in bleached hair, S100A3 is irreversibly oxidized upon bleaching treatment. It is likely that the oxidative cleavage of disulfide bonds between cuticle-constituting proteins, including S100A3, results in the fragile property of cuticles. Here we present a more comprehensive model of hair damage based on a diverse mechanism of cuticle delamination.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Munksgaard International Publishers
    Allergy 60 (2005), S. 0 
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background:  Goblet cell metaplasia is a pathologic characteristic of asthma, associated with excess mucus secretion. Interleukin (IL)-4 and IL-13 plays an important role in mucus hypersecretion. Suplatast tosilate (suplatast), an antiallergic agent, is a Th2 cytokine inhibitor that suppresses the synthesis of IL-4, IL-5, IL-13, and eosinophilic airway inflammation.Objective:  We examined the effects of suplatast on mucus production in bronchial biopsy specimens taken from asthmatic subjects.Methods:  Oral suplatast 300 mg daily, or placebo was administered for 3 months in a double-blind, parallel-group study in 25 patients with asthma. Biopsy specimens were evaluated at before and after treatment for alcian blue/period acid-Schiff (AB/PAS), MUC5AC staining in bronchial epithelium and IL-4+, IL-13+ cells as well as inflammatory cells in lamina propria.Results:  There were significant decreases in the percentage of AB/PAS (P 〈 0.01) and MUC5AC (P 〈 0.01) stained area in the suplatast group. These changes were accompanied by significant decreases in IL-4+ and IL-13+ cells in suplatast-treated subjects. Additionally, we have observed that the number of infiltrating eosinophils and CD4+ T cells significantly decreased.Conclusions:  These findings suggest that suplatast prevents goblet cell metaplasia through modulation of Th2 cytokine production and the recruitment of eosinophils and CD4+ T cells in the asthmatic airways.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background  Dapsone (4,4′-diaminodiphenyl sulphone) is a powerful therapeutic tool in many skin diseases including neutrophilic dermatoses. The drug has an outstanding therapeutic efficacy against many skin diseases characterized by neutrophil-rich infiltrates; however, mechanisms of its action are poorly understood.Objectives  We investigated the effects of dapsone on respiratory and secretory functions of human neutrophils triggered by the chemotactic peptide N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP), the physiological agonist C5a, and phorbol myristate acetate (PMA).Methods  Human neutrophils were isolated from venous blood obtained from healthy donors. We detected extracellular production of superoxide (O2–) by cytochrome C reduction assay, and intracellular production of O2– by flow cytometry. Neutrophil elastase release was measured by the cleavage of the specific elastase substrate N-methoxysuccinyl-Ala-Ala-Pro-Val-p-nitroanilide. Measurement of cytosolic free calcium concentration was performed using the calcium-reactive fluorescence probe, Fluo-3.Results  Dapsone suppressed intra- and extracellular production of O2– and elastase release triggered by fMLP and C5a, but not by PMA. Both fMLP and C5a signalled the above pathways by inducing calcium influx, but PMA functions bypassed calcium influx. Dapsone was capable of antagonizing the induction of calcium influx.Conclusions  These findings suggest that one mechanism of the anti-inflammatory action of dapsone is inhibition of calcium-dependent functions of neutrophils including release of tissue-damaging oxidants and proteases in the affected skin.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: In this study, Fe-2.0Si-4.6C (mass%) gray cast iron disk specimens with three differentmatrix phases were coated with MoS2 using pressure spraying, and the friction and wear propertiesof the specimens were investigated against AISI52100 steel and polytetrafluoroethylene balls underthe lubrication of oil using an Optimol SRV friction tester. When AISI52100 steel balls were usedas the paired material, all of the MoS2-coated gray cast iron specimens showed lower frictioncoefficients and higher wear resistance than the non-coated disk specimens. On the other hand,MoS2-coated gray cast iron specimens exhibited higher friction coefficients than non-coated diskspecimens for the most part, when polytetrafluoroethylene balls were used as the paired material
    Type of Medium: Electronic Resource
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