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  • Articles: DFG German National Licenses  (27)
  • 2000-2004  (8)
  • 1995-1999  (11)
  • 1990-1994  (7)
  • 1965-1969  (1)
  • 1
    ISSN: 1432-0533
    Keywords: Key words Cytosine arabinoside ; Heterotopia ; Microcephaly ; Hippocampus ; Immunohistochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Pregnant mice were injected intraperitoneally with cytosine arabinoside (Ara-C) on days 13.5 and 14.5 of pregnancy. The brains of their offspring were studied histologically and histochemically. In addition to dysgenic microcephaly, nodular structures consisting of cells with a relatively homogeneous morphology were observed in the depths of the cerebral cortex. The cell clusters were first seen around postnatal day 4, and had a cellular continuity with the disarrayed pyramidal cell layer in the CA1 region of the hippocampus. Golgi-Cox staining showed a number of pyramidal-shaped cells in the clusters. Morphologically, they resembled the pyramidal neurons of the hippocampus. Immunohistochemical examination, using anti-serotonin or anti-tyrosine hydroxylase antibodies, also indicated similarities between the cell clusters and the pyramidal cell layer. It is, therefore, proposed that the cell clusters consisted of heterotopic pyramidal cells of the hippocampus. A few synaptic structures could already be detected in the heterotopic cell clusters on postnatal day 3 by electron microscopy. This early establishment of synaptic contact with related neurons may have caused the heterotopic localization of the pyramidal cells.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Determination of low molecular weight carbohydrates in marine environments indicated that 1-O-β-D-galactosylglycerol, 6-O-α-D-galactosyl-1-O-β-D-galacto-sylglycerol, sucrose, laminaribiose and laminaritriose are widely distributed in seawaters, suspended and sinking particles, and sediments in coastal as well as in deep-sea waters [e.g. Mikawa Bay and Sagami Bay, Kumano Nada (offshore Japan), and northwest North Pacific Ocean, Bering Sea and Antarctic Ocean: collections during 1978–1984]. Identification of these glycosylglycerols and oligosaccharides in algal cells such as a flagellate (Olisthodisus luteus), blue-green algae (e.g.Trichodesmium sp.) and a diatom (Reptocylindrus denicus) strongly suggests that these sugars are photosynthetically produced by algae in the euphotic zone and are then rapidly transported to the deep sea as sinking particles which can be collected by sediment-trap experiments. The rapid decay rate of low molecular weight carbohydrates by microorganisms suggests that the transported sugars provide energy substrates for microorganisms living in the deep sea.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 171 (1999), S. 0 
    ISSN: 1574-6968
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Light-dependent H2 evolution did not occur in nitrogen-deprived cultures of Rhodovulum sulfidophilum in the presence of ethanol. When ethanol was added to cells which had been grown with ammonia, derepression of the nitrogen fixation genes (nifHD) was inhibited at an ethanol concentration of 1 mM. On the other hand, when cells had nitrogenase-catalyzed proton-reducing activity prior to ethanol addition, reduction of the nifHD transcript level did not occur after the addition. In cells grown with ammonia, concomitant addition of an auxiliary oxidant such as dimethylsulfoxide or sodium bicarbonate resulted in derepression of nitrogenase activity in the presence of ethanol. These results suggest that the electron-accepting process is necessary for derepression of nif genes in cultures which use ethanol as the electron donor.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Only a small proportion of the mouse genome is transcribed into mature messenger RNA transcripts. There is an international collaborative effort to identify all full-length mRNA transcripts from the mouse, and to ensure that each is represented in a physical collection of clones. Here we report the ...
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 16 (1969), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract— —An enzyme catalysing the transfer of sulphate from 3′-phosphoadenylsulphate to serotonin was purified from rabbit brain. The purification procedure involved ammonium sulphate fractionation of the 200,000 g supernatant of rabbit brain homogenate, treatment with alumina Cγ, and chromatography on DEAE-cellulose. The enzyme was purified 67-fold from the 200,000 g supernatant of the brain homogenate. The intracranial distribution of the sulphotransferase was investigated and the cerebellum found to have rather high activity. The sulphotransferase activities of rabbit, dog, rat and bovine brains were compared; rabbit brain had the highest activity, followed by dog, rat and bovine brain.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Inc
    Journal of metamorphic geology 20 (2002), S. 0 
    ISSN: 1525-1314
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: Regional variation in the P–T path of the Sambagawa metamorphic rocks, central Shikoku, Japan has been inferred from compositional zoning of metamorphic amphibole. Rocks constituting the northern part (Saruta River area) exhibit a hairpin type P–T path, where winchite/actinolite grew at the prograde stage, the peak metamorphism was recorded by the growth of barroisite to hornblende and sodic amphibole to winchite/actinolite grew at the retrograde stage. In the southern part (Asemi River area), rocks exhibit a clockwise type P–T path, where barroisite to hornblende core is rimmed by winchite to actinolite. The difference in P–T path could suggest a faster exhumation rate (i.e. more rapid decompression) in the southern than in the northern part. On the other hand, physical conditions of deformation during the exhumation stage have been independently inferred from microstructures in deformed quartz. Recrystallized quartz grains in rocks from the low-grade (chlorite and garnet) zones are much more stretched in the southern part (aspect ratio ≥ 4.0) than in the northern part (aspect ratio〈 4.0), indicating a higher strain rate in the former than in the latter. These facts may indicate that the exhumation and strain rates are correlated (i.e. the exhumation rate increases with increasing the strain rate). The difference in the exhumation rate inferred from amphibole zoning between the northern and southern parts could be explained by an extensional model involving normal faulting, where the lower plate can be exhumed faster than the upper plate due to the displacement along the fault. Furthermore, the model may explain the positive correlation between the exhumation and strain rates, because the lower plate tended to support more stress than the upper plate.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 66 (1995), S. 1993-1995 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: Calculations of the radiation from a four-period polarizing undulator by use of the general radiation equation and numerical integration including the effects of electron-beam emittance, energy spread, and finite observation distance are presented. Accurate electron-beam profiles have been experimentally determined and modeled by the Monte Carlo method. Good agreement is found in spectral intensity between the measured and calculated spectra. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 66 (1995), S. 1592-1594 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: We developed a polarization modulation spectroscopy in the extreme ultraviolet (XUV) region for magnetic circular dichroism (MCD) measurements. We used a polarizing undulator with crossed and retarded magnetic fields. It enables us to obtain radiation adjusting the polarization states arbitrarily and rapidly. The undulator is essential in our polarization modulation spectroscopy for MCD study in the XUV region. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A polarizing undulator has been constructed utilizing crossed and retarded magnetic fields that can provide arbitrary polarized radiation. The absolute brightness and polarization characteristics have been studied in the visible region from 350–700 nm at 230 MeV of stored electron energy by varying the observation angle θ. Any desired elliptically polarized radiation was obtainable by adjusting the retardation between the two pairs of magnet arrays.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 63 (1993), S. 580-582 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A simple and flexible method is presented for generating a partially coherent light which obtains the highly smooth focused beam pattern. The beam divergence of 32 times diffraction limited light having a spectral width of 1.6 nm has been easily and reproducibly achieved by injecting a laser pulse from an actively mode-locked Nd:YLF oscillator to a single mode optical fiber, coupled to a multimode optical fiber. Temporal evolution of the beam smoothing due to the induced incoherency was examined with temporally resolved measurements of the beam pattern. The partially coherent light was focused through a random phase plate after the amplification. Small-scale intensity perturbation in a focused beam pattern was greatly reduced.
    Type of Medium: Electronic Resource
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