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  • 1
    Electronic Resource
    Electronic Resource
    Constant involvement of the Betz cells and pyramidal tract in multiple system atrophy: a clinicopathological study of seven autopsy cases (2000)
    Springer
    Acta neuropathologica 99 (2000), S. 628-636 
    Details
    ISSN: 1432-0533
    Keywords: Key words Betz cells ; Multiple system atrophy ; Neuropathology ; Pyramidal signs ; Pyramidal tract ¶degeneration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We investigated clinicopathologically the pyramidal signs, including spasticity, hyperreflexia, and Babinski’s sign, and the involvement of the pyramidal tract and primary motor cortex, in seven Japanese autopsy cases of multiple system atrophy (MSA). Pyramidal signs were observed in six (86%) of the seven autopsy cases. Hyperreflexia and Babinski’s sign were each evident in five patients, but spasticity was observed in only one patient. Loss of Betz cells and presence of glial cytoplasmic inclusions in the primary motor cortex were noticed in all seven cases. Astrocytosis in the fifth layer of the primary motor cortex was noticed in five cases, but its presence was not related to the duration of the disease. Involvement of the pyramidal tract in the spinal cord, particularly of the small myelinated fibers, was observed in all seven cases, but no involvement of the pyramidal tract in the midbrain was evident in any of the six cases in which this structure was examined. In MSA, pyramidal signs were shown to be present more frequently than believed before, and the clinicopathological correlation between pyramidal signs and involvement of the pyramidal tract was obvious. Constant involvement of Betz cells in MSA has not been reported. Our clinicopathological findings may also make a contribution to the understanding of the clinicopathological hallmarks of MSA.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004010051173
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  • 2
    Electronic Resource
    Electronic Resource
    Familial amyotrophic lateral sclerosis with onset in bulbar sign, benign clinical course, and Bunina bodies: a clinical, genetic, and pathological study of a Japanese family (2000)
    Springer
    Acta neuropathologica 100 (2000), S. 603-607 
    Details
    ISSN: 1432-0533
    Keywords: Key words Bunina bodies ; Cu/Zn superoxide ; dismutase ; Familial amyotrophic lateral sclerosis ; Neuropathology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report a Japanese family with autosomal dominant adult-onset amyotrophic lateral sclerosis (FALS) with onset in the bulbar musculature, clinically benign course, absence of the Cu/Zn superoxide dismutase-1 (SOD 1) gene mutation, and many Bunina bodies, in addition to involvement of the upper and lower motor neurons. The proband was a Japanese woman who was 66 years old at the time of death. Family history disclosed five patients with FALS over three generations. She developed dysarthria at age 57, followed by dysphagia, muscle weakness of the upper extremities, and difficulty in respiration. She could walk without support until her death. The elder sister of the proband developed dysarthria at age 48 and died at age 58. A genetic study of the nephew of the proband showed the absence of a mutation in the SOD 1 gene. Neuropathological examination of the proband disclosed neuronal loss in the upper and lower motor neurons, and numerous Bunina bodies in the lower motor neurons without Lewy body-like inclusions or ubiquitin-immunoreactive neuronal inclusions. No degeneration of the Clarke’s column, middle root zone of the posterior column, or posterior spinocerebellar tract was present. Review of the literature revealed that only patients with FALS with a long survival period of over 5 years had pathological findings consistent with FALS with posterior column involvement. This study contributes to the elucidation of the clinicopathological heterogeneity of FALS.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004010000237
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  • 3
    Electronic Resource
    Electronic Resource
    MR cisternography using a three-dimensional half-Fourier single-shot fast spin-echo sequence (1998)
    Springer
    European radiology 8 (1998), S. 424-426 
    Details
    ISSN: 1432-1084
    Keywords: Key words: Cisternography ; MR imaging ; Half-Fourier imaging ; Cranial nerves
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Application of a three-dimensional half-fourier single-shot fast spin-echo sequence to MR cisternography is presented. This technique is capable of demonstrating normal cranial nerves. It is also useful in screening for acoustic neuroma as well as in the diagnosis of neurovascular compression.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003300050405
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  • 4
    Electronic Resource
    Electronic Resource
    The Japanese food distribution system and the Large Scale Retail Store Law (1997)
    Bingley : Emerald
    International journal of social economics 24 (1997), S. 197-206 
    Details
    ISSN: 0306-8293
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: Spotlights important developments in the Japanese food distribution system over the past two to three years. States that, foreign pressure, combined with economic and social change in Japan, has forced the Japanese Government to alter some government regulations, including the Large Scale Retail Store Law. Reports that these regulatory changes, combined with other changes in the Japanese economy and society, have led to an increase in the number of supermarkets in Japan, and also to an expansion in the number of convenience stores and mini supermarkets. Discusses these developments and outlines possible implications for foreign firms interested in selling into the Japanese food market.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1108/03068299710161214
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  • 5
    Electronic Resource
    Electronic Resource
    Phenotypic and genetic characterization of Erwinia carotovora from mulberry (Morus spp.) (2003)
    Oxford, UK : Blackwell Science Ltd
    Plant pathology 52 (2003), S. 0 
    Details
    ISSN: 1365-3059
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Phenotypic and genetic characteristics of nine bacterial strains isolated from mulberry (Morus spp.), which were originally described as Erwinia carotovora ssp. carotovora (Ecc), were investigated. Based on the results of biochemical tests, these bacterial strains were divided into two different types, type 1 and type 2. Two strains of type 1 were similar to Ecc, whereas seven strains of type 2 were distinct from Ecc. A polyphasic study that included serological assay, specific PCR assay for E. carotovora ssp. atroseptica (Eca), PCR-RFLP of a pectate lyase (pel) gene and RAPD-PCR was performed on the type 2 strains, and the data were compared with those of related E. carotovora subspecies. The results of serological and specific PCR assays for Eca showed that the type 2 strains were distinct from Eca. In RFLP analysis of the pel gene using Sau3AI, the type 2 strains showed a unique RFLP pattern. On the basis of RAPD analysis, similarity of RAPD patterns within the type 2 strains was very high. A unique RAPD fragment was isolated from the type 2 strains and used as a probe for Southern hybridization. This probe hybridized only with PCR products from the type 2 strains. Based on phenotypic, serological and genetic characteristics, the type 2 strains isolated from mulberry may belong to a distinct E. carotovora subspecies other than Eca or Ecc.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-3059.2003.00816.x
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  • 6
    Electronic Resource
    Electronic Resource
    Subcutaneous nodules on the buttocks as a manifestation of dialysis-related amyloidosis: a clinicopathological entity? (2003)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 149 (2003), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary  While β2-microglobulin amyloidosis occurring in patients undergoing long-term dialysis is frequently associated with joint involvement, skin lesions have rarely been encountered. We report a 57-year-old man with extensive subcutaneous amyloid deposition forming large nodules on the buttocks; the patient had been on maintenance dialysis for 28 years. Although this condition is rare, a review of the literature indicates that the majority of such lesions occur around the buttock region.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2133.2003.05466.x
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  • 7
    Electronic Resource
    Electronic Resource
    Reconstruction for the brilliance-upgrading project of the Photon Factory storage ring (1998)
    Chester : International Union of Crystallography (IUCr)
    Journal of synchrotron radiation 5 (1998), S. 366-368 
    Details
    ISSN: 1600-5775
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Geosciences , Physics
    Notes: Reconstruction of the Photon Factory storage ring (PF ring; 2.5 GeV) is now in progress to provide very brilliant synchrotron radiation to users, i.e. the emittance is being reduced by a factor of five. Components, such as the quadrupole and sextupole magnets, vacuum chambers, beamlines and beam-position monitors, are being replaced by new ones in 16 normal-cell sections of the PF ring. The accelerating cavities, injection systems and control systems are also being replaced. Operation will commence when the improvements are completed on 1 October 1997.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0909049597014118
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  • 8
    Electronic Resource
    Electronic Resource
    Operation of an X-ray Undulator in the Tristan Main Ring as a Prototype of Future Super Light Sources (1997)
    Chester : International Union of Crystallography (IUCr)
    Journal of synchrotron radiation 4 (1997), S. 54-59 
    Details
    ISSN: 1600-5775
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Geosciences , Physics
    Notes: A 5.4 m-long 239-pole undulator comprising three rigid and precise standardized-unit undulators was completed and installed in the Tristan main ring, which was operated as a light source at a beam energy from 8 to 10 GeV. This undulator was successfully tested, characterized and used as a brilliant hard X-ray source for several synchrotron radiation experiments during the last 3.5 months of 1995.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0909049596015713
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  • 9
    Electronic Resource
    Electronic Resource
    Adaptive modification of membrane phospholipid fatty acid composition and metabolic thermosuppression of brown adipose tissue in heat-acclimated rats (2000)
    Springer
    International journal of biometeorology 43 (2000), S. 163-168 
    Details
    ISSN: 1432-1254
    Keywords: Key words Brown adipose tissue ; Fatty acid profile ; Docosahexaenoic acid (DHA) ; Heat acclimation ; In vitro oxygen consumption
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Notes: Abstract  Thermogenesis, especially facultative thermogenesis by brown adipose tissue (BAT), is less important in high ambient temperature and the heat-acclimated animals show a lower metabolic rate. Adaptive changes in the metabolic activity of BAT are generally found to be associated with a modification of membrane phospholipid fatty acid composition. However, the effect of heat acclimation on membrane phospholipid fatty acid composition is as yet unknown. In this study, we examined the thermogenic activity and phospholipid fatty acid composition of interscapular BAT from heat-acclimated rats (control: 25±1°C, 50% relative humidity and heat acclimation: 32±0.5°C, 50% relative humidity). Basal thermogenesis and the total thermogenic capacity after noradrenaline stimulation, as estimated by in vitro oxygen consumption of BAT (measured polarographically using about 1-mm3 tissue blocks), were smaller in the heat-acclimated group than in the control group. There was no difference in the tissue content of phospholipids between the groups when expressed per microgram of DNA. The phospholipid fatty acid composition was analyzed by a capillary gas chromatograph. The state of phospholipid unsaturation, as estimated by the number of double bonds per fatty acid molecule, was similar between the groups. The saturated fatty acid level was higher in the heat-acclimated group. Among the unsaturated fatty acids, heat acclimation decreased docosahexaenoic acid and oleic acid levels, and increased the arachidonic acid level. The tissue level of docosahexaenoic acid correlated with the basal oxygen consumption of BAT (r=0.6, P〈0.01) and noradrenaline-stimulated maximum values of oxygen consumption (r=0.5, P〈0.05). Our results show that heat acclimation modifies the BAT phospholipid fatty acids, especially the n-3 polyunsaturated fatty acid docosahexaenoic acid, which is possibly involved in the metabolic thermosuppression.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004840050003
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  • 10
    Electronic Resource
    Electronic Resource
    A new MRI technique for demonstrating the surface of the brain together with the cortical veins (1999)
    Springer
    Neuroradiology 41 (1999), S. 425-427 
    Details
    ISSN: 1432-1920
    Keywords: Key words Brain ; anatomy ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We assessed combining of surface-anatomy scanning (SAS) MRI and MR venography (MRV). We obtained SAS images with a half-Fourier single-shot fast spin-echo sequence, then MRV of the identical section with a two-dimensional phase-contrast technique. We then added the two sets of images. The combined images, which were obtained within 10 min, provided information about the surface anatomy and cortical veins. This simple technique is useful for demonstrating brain surface structures, especially in patients from whom one plans to excise a lesion.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002340050776
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